LU84468A1 - Medicaments a haut degre de solubilite et procede pour leur obtention - Google Patents

Medicaments a haut degre de solubilite et procede pour leur obtention Download PDF

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Publication number
LU84468A1
LU84468A1 LU84468A LU84468A LU84468A1 LU 84468 A1 LU84468 A1 LU 84468A1 LU 84468 A LU84468 A LU 84468A LU 84468 A LU84468 A LU 84468A LU 84468 A1 LU84468 A1 LU 84468A1
Authority
LU
Luxembourg
Prior art keywords
solubility
inhibiting
stabilizer
medicaments according
atomization
Prior art date
Application number
LU84468A
Other languages
English (en)
French (fr)
Inventor
Owen I Dr Corrigan
Donald E Panoz
Original Assignee
Elan Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Ltd filed Critical Elan Corp Ltd
Publication of LU84468A1 publication Critical patent/LU84468A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
LU84468A 1982-04-19 1982-11-12 Medicaments a haut degre de solubilite et procede pour leur obtention LU84468A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8206646 1982-04-19
FR8206646A FR2525108B1 (fr) 1982-04-19 1982-04-19 Medicaments a haut degre de solubilite et procede pour leur obtention

Publications (1)

Publication Number Publication Date
LU84468A1 true LU84468A1 (fr) 1983-06-13

Family

ID=9273120

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84468A LU84468A1 (fr) 1982-04-19 1982-11-12 Medicaments a haut degre de solubilite et procede pour leur obtention

Country Status (18)

Country Link
US (2) US4610875A (it)
JP (1) JPS58183615A (it)
AR (1) AR230183A1 (it)
AT (1) AT389813B (it)
AU (1) AU555579B2 (it)
BE (1) BE894942A (it)
CA (1) CA1225029A (it)
CH (1) CH655003A5 (it)
DE (1) DE3241097A1 (it)
ES (1) ES517444A0 (it)
FR (1) FR2525108B1 (it)
GB (1) GB2119784B (it)
IE (1) IE54084B1 (it)
IT (1) IT1153099B (it)
LU (1) LU84468A1 (it)
NL (1) NL8204461A (it)
PT (1) PT75867B (it)
SE (1) SE8206697L (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722984A1 (fr) * 1994-07-26 1996-02-02 Effik Laboratoires Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees

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FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
JPS60139688A (ja) * 1983-12-28 1985-07-24 Tokyo Tanabe Co Ltd 無定形ジヒドロピリジン粉末製剤
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US4798725A (en) * 1986-06-16 1989-01-17 Norwich Eaton Pharmaceuticals, Inc. Sustained release capsule
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JPH0648937A (ja) * 1992-04-07 1994-02-22 Seitai Kagaku Kenkyusho:Kk 経口投与に適する薬剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
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US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
WO1997034601A1 (fr) * 1996-03-18 1997-09-25 Eisai Co., Ltd. Compositions medicamenteuses a solubilite amelioree
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
AU763309B2 (en) * 1998-07-20 2003-07-17 Smithkline Beecham Corporation Bioenhanced formulations comprising eprosartan in oral solid dosage form
EP1120120A4 (en) 1998-10-05 2009-04-29 Eisai R&D Man Co Ltd TABLETS DISSOLVING DIRECTLY IN MOUTH
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
JP5767429B2 (ja) * 1999-11-12 2015-08-19 アッヴィ・インコーポレイテッド 固体分散剤中の結晶化阻害剤
DE60038162T2 (de) * 1999-12-08 2009-02-26 Pharmacia Corp. Celecoxib in festkörperform mit erhöhter bioverfügbarkeit
EP1712222A3 (en) 1999-12-23 2012-06-20 Pfizer Products Inc. Pharmaceutical compositions providing enhanced drug concentrations
IL134701A0 (en) * 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
CA2412776C (en) 2000-06-16 2011-03-15 Mitsubishi Pharma Corporation Compositions controlling release ph range and/or speed
AU2001295999A1 (en) * 2000-10-24 2002-05-06 Ajinomoto Co., Inc. Nateglinide-containing preparations
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
JP2004534811A (ja) * 2001-06-22 2004-11-18 ファイザー・プロダクツ・インク ポリマーと薬剤の集合体を含む医薬組成物
PL367674A1 (en) * 2001-06-22 2005-03-07 Pfizer Products Inc. Pharmaceutical compositions of adsorbates of amorphous drug
SI21223A (sl) * 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
US20050152932A1 (en) * 2003-06-12 2005-07-14 Valery Normand Non-crystalline perfume or flavor delivery system
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050048112A1 (en) 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
CA2591983A1 (en) * 2004-12-20 2006-06-29 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions comprising amorphous benzimidazole compounds
JP5284777B2 (ja) * 2005-04-11 2013-09-11 アボット・ラボラトリーズ 難溶性薬剤の改善された溶解プロファイルを有する医薬組成物
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
WO2007086039A1 (en) * 2006-01-27 2007-08-02 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin A method of producing porous microparticles
PT103743B (pt) * 2007-05-16 2013-01-15 Hovione Farmaciencia S A Processo para preparar derivados de 21-disódio fosfato de pregnanos.
CA2742356A1 (en) * 2008-11-04 2010-05-14 Cipla Limited Tiotropium bromide having a low degree of crystallinity
CN103260609B (zh) * 2010-12-23 2017-08-11 雅培股份有限两合公司 基于固体分散体的固体延缓制剂
EP2714683A4 (en) 2011-05-27 2014-11-05 Hetero Research Foundation RITONAVIR AMORPH CO-PRECIPITATION

Family Cites Families (20)

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US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
JPS5163925A (ja) * 1974-11-30 1976-06-02 Kyowa Hakko Kogyo Kk Muteikeikuroramufuenikooruno seizoho
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
JPS51118816A (en) * 1975-04-08 1976-10-19 Meiji Seika Kaisha Ltd A process for stabilizing non-crystalloidal solid
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
JPS587609B2 (ja) * 1979-06-17 1983-02-10 フロイント産業株式会社 粉体薬剤のコ−テング法
JPS55139319A (en) * 1979-04-13 1980-10-31 Furointo Sangyo Kk Activation of drug soluble in alkali and acid
JPS6024768B2 (ja) * 1979-06-16 1985-06-14 フロイント産業株式会社 活性化薬剤の製法
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS5948810B2 (ja) * 1980-03-22 1984-11-29 山之内製薬株式会社 ニカルジピン持続性製剤用組成物
JPS5646837A (en) * 1979-09-27 1981-04-28 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen clathrate compound
JPS5655370A (en) * 1979-10-13 1981-05-15 Kyorin Pharmaceut Co Ltd Amorphous nicomol
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2722984A1 (fr) * 1994-07-26 1996-02-02 Effik Laboratoires Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
WO1997004749A1 (fr) * 1994-07-26 1997-02-13 Laboratoires Effik Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
EP0761208A1 (fr) * 1994-07-26 1997-03-12 Laboratoires EFFIK Procédé de préparation de formes pharmaceutiques sèches et les compositions ainsi réalisées

Also Published As

Publication number Publication date
AT389813B (de) 1990-02-12
US4610875A (en) 1986-09-09
GB2119784B (en) 1986-04-03
FR2525108A1 (fr) 1983-10-21
ES8505249A1 (es) 1985-05-16
IE54084B1 (en) 1989-06-07
DE3241097A1 (de) 1983-10-20
ES517444A0 (es) 1985-05-16
IT8224368A0 (it) 1982-11-23
GB2119784A (en) 1983-11-23
AU9043182A (en) 1983-10-27
SE8206697L (sv) 1983-10-20
JPS58183615A (ja) 1983-10-26
NL8204461A (nl) 1983-11-16
IT8224368A1 (it) 1984-05-23
AR230183A1 (es) 1984-03-01
IE822610L (en) 1983-10-19
FR2525108B1 (fr) 1989-05-12
SE8206697D0 (sv) 1982-11-24
IT1153099B (it) 1987-01-14
PT75867B (fr) 1986-01-21
US4769236A (en) 1988-09-06
CH655003A5 (fr) 1986-03-27
JPH0341444B2 (it) 1991-06-24
PT75867A (fr) 1982-12-01
CA1225029A (en) 1987-08-04
BE894942A (fr) 1983-05-09
AU555579B2 (en) 1986-10-02
ATA427282A (de) 1989-07-15
DE3241097C2 (it) 1989-04-13

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