LT2766393T - Antikūnai prieš htra1 ir jų naudojimo būdai - Google Patents

Antikūnai prieš htra1 ir jų naudojimo būdai

Info

Publication number
LT2766393T
LT2766393T LTEP12840084.3T LT12840084T LT2766393T LT 2766393 T LT2766393 T LT 2766393T LT 12840084 T LT12840084 T LT 12840084T LT 2766393 T LT2766393 T LT 2766393T
Authority
LT
Lithuania
Prior art keywords
methods
htra1 antibodies
htra1
antibodies
Prior art date
Application number
LTEP12840084.3T
Other languages
English (en)
Lithuanian (lt)
Inventor
Yan Wu
Menno Van Lookeren-Campagne
Daniel Kirchhofer
Michael Terry LIPARI
Katschke, Jr.
Paul M. Moran
Scott Stawicki
Wei-Ching Liang
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of LT2766393T publication Critical patent/LT2766393T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
LTEP12840084.3T 2011-10-14 2012-10-12 Antikūnai prieš htra1 ir jų naudojimo būdai LT2766393T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161547649P 2011-10-14 2011-10-14
PCT/US2012/059878 WO2013055998A1 (en) 2011-10-14 2012-10-12 ANTI-HtrA1 ANTIBODIES AND METHODS OF USE

Publications (1)

Publication Number Publication Date
LT2766393T true LT2766393T (lt) 2018-10-10

Family

ID=48082468

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP12840084.3T LT2766393T (lt) 2011-10-14 2012-10-12 Antikūnai prieš htra1 ir jų naudojimo būdai

Country Status (33)

Country Link
US (3) US9738727B2 (cg-RX-API-DMAC10.html)
EP (2) EP2766393B1 (cg-RX-API-DMAC10.html)
JP (2) JP6532678B2 (cg-RX-API-DMAC10.html)
KR (2) KR102102862B1 (cg-RX-API-DMAC10.html)
CN (2) CN108373506A (cg-RX-API-DMAC10.html)
AR (1) AR088322A1 (cg-RX-API-DMAC10.html)
AU (2) AU2012322618A1 (cg-RX-API-DMAC10.html)
BR (1) BR112014008862A2 (cg-RX-API-DMAC10.html)
CA (1) CA2850032C (cg-RX-API-DMAC10.html)
CL (1) CL2014000888A1 (cg-RX-API-DMAC10.html)
CO (1) CO7020870A2 (cg-RX-API-DMAC10.html)
CR (1) CR20140212A (cg-RX-API-DMAC10.html)
DK (1) DK2766393T3 (cg-RX-API-DMAC10.html)
EA (1) EA201490778A1 (cg-RX-API-DMAC10.html)
ES (1) ES2687951T3 (cg-RX-API-DMAC10.html)
HK (1) HK1255608A1 (cg-RX-API-DMAC10.html)
HR (1) HRP20181457T1 (cg-RX-API-DMAC10.html)
HU (1) HUE039133T2 (cg-RX-API-DMAC10.html)
IL (1) IL232055B (cg-RX-API-DMAC10.html)
LT (1) LT2766393T (cg-RX-API-DMAC10.html)
MA (1) MA35712B1 (cg-RX-API-DMAC10.html)
MX (2) MX372661B (cg-RX-API-DMAC10.html)
PE (1) PE20141562A1 (cg-RX-API-DMAC10.html)
PH (1) PH12014500841B1 (cg-RX-API-DMAC10.html)
PL (1) PL2766393T3 (cg-RX-API-DMAC10.html)
PT (1) PT2766393T (cg-RX-API-DMAC10.html)
RS (1) RS57645B1 (cg-RX-API-DMAC10.html)
SG (1) SG11201401477XA (cg-RX-API-DMAC10.html)
SI (1) SI2766393T1 (cg-RX-API-DMAC10.html)
TR (1) TR201811270T4 (cg-RX-API-DMAC10.html)
TW (1) TW201321414A (cg-RX-API-DMAC10.html)
WO (1) WO2013055998A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201402172B (cg-RX-API-DMAC10.html)

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MX2016001854A (es) 2013-08-12 2016-09-06 Genentech Inc Composiciones y metodo para tratar condiciones asociadas con el complemento.
SG11201608868PA (en) 2014-05-01 2016-11-29 Genentech Inc Anti-factor d antibody variants and uses thereof
JP6929771B2 (ja) 2014-11-10 2021-09-01 ジェネンテック, インコーポレイテッド 抗インターロイキン−33抗体及びその使用
BR112018007703A2 (pt) * 2015-10-30 2018-11-06 Genentech Inc anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
TW201730211A (zh) 2015-10-30 2017-09-01 建南德克公司 抗因子d抗體及結合物
JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック, インコーポレイテッド 抗d因子抗体変異体コンジュゲート及びその使用
WO2017075259A1 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody formulations
JP7164521B2 (ja) 2016-06-21 2022-11-01 オリオン・オフサルモロジー・エルエルシー 炭素環式プロリンアミド誘導体
JP7179721B2 (ja) 2016-06-21 2022-11-29 オリオン・オフサルモロジー・エルエルシー 複素環式プロリンアミド誘導体
JP2018096930A (ja) * 2016-12-16 2018-06-21 公益財団法人ヒューマンサイエンス振興財団 加齢黄斑変性の診断マーカー、診断キット、診断補助方法、及び、発症リスク判定方法
US20200377573A1 (en) * 2016-12-22 2020-12-03 Daiichi Sankyo Company, Limited Peptide for treating age-related macular degeneration
US11453718B2 (en) 2017-03-27 2022-09-27 The Schepens Eye Research Institute, Inc. NOTCH3 agonist compositions and methods for treating small vessel diseases
US20200103419A1 (en) 2017-03-27 2020-04-02 The Schepens Eye Research Institute, Inc. Blood biomarkers and diagnostic methods for small vessel diseases
CA3085211A1 (en) * 2017-12-21 2019-06-27 F. Hoffmann-La Roche Ag Companion diagnostic for htra1 rna antagonists
TWI906202B (zh) * 2018-06-21 2025-12-01 日商第一三共股份有限公司 視網膜色素變性治療用胜肽之用途
TW202039585A (zh) * 2018-11-16 2020-11-01 美商雙子治療公司 靶向htra1之基於抗體之療法及使用方法
WO2020109343A1 (en) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Combination therapy for treatment of macular degeneration
SG11202106452YA (en) * 2018-12-24 2021-07-29 Visterra Inc Methods for identifying epitopes and paratopes
CA3136119A1 (en) 2019-04-10 2020-10-15 University Of Utah Research Foundation Htra1 modulation for treatment of amd
EP4118114A1 (en) 2020-03-13 2023-01-18 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
CA3187837A1 (en) * 2020-08-04 2022-02-10 Exelixis, Inc. Cd47 binding agents and uses thereof
US20220251241A1 (en) * 2021-02-08 2022-08-11 Ngm Biopharmaceuticals, Inc. Htra1-binding agents and methods of use thereof

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