HK1255608A1 - 抗htra1抗體及使用方法 - Google Patents

抗htra1抗體及使用方法

Info

Publication number
HK1255608A1
HK1255608A1 HK18114739.7A HK18114739A HK1255608A1 HK 1255608 A1 HK1255608 A1 HK 1255608A1 HK 18114739 A HK18114739 A HK 18114739A HK 1255608 A1 HK1255608 A1 HK 1255608A1
Authority
HK
Hong Kong
Prior art keywords
methods
htra1 antibodies
htra1
antibodies
Prior art date
Application number
HK18114739.7A
Other languages
English (en)
Inventor
吳岩
門諾‧凡盧克倫-康帕涅
丹尼爾‧柯克霍弗
邁克爾‧特裏里‧利帕里
小肯尼思‧J‧卡奇克
保羅‧M‧莫蘭
斯科特‧斯塔維奇
梁偉慶
Original Assignee
霍夫曼-拉羅奇有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍夫曼-拉羅奇有限公司 filed Critical 霍夫曼-拉羅奇有限公司
Publication of HK1255608A1 publication Critical patent/HK1255608A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
HK18114739.7A 2011-10-14 2018-11-19 抗htra1抗體及使用方法 HK1255608A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161547649P 2011-10-14 2011-10-14

Publications (1)

Publication Number Publication Date
HK1255608A1 true HK1255608A1 (zh) 2019-08-23

Family

ID=48082468

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18114739.7A HK1255608A1 (zh) 2011-10-14 2018-11-19 抗htra1抗體及使用方法

Country Status (32)

Country Link
US (3) US9738727B2 (zh)
EP (2) EP3461839A1 (zh)
JP (2) JP6532678B2 (zh)
KR (2) KR102102862B1 (zh)
CN (2) CN103917556B (zh)
AR (1) AR088322A1 (zh)
AU (2) AU2012322618A1 (zh)
BR (1) BR112014008862A2 (zh)
CA (1) CA2850032C (zh)
CL (1) CL2014000888A1 (zh)
CO (1) CO7020870A2 (zh)
CR (1) CR20140212A (zh)
DK (1) DK2766393T3 (zh)
EA (1) EA201490778A1 (zh)
ES (1) ES2687951T3 (zh)
HK (1) HK1255608A1 (zh)
HR (1) HRP20181457T1 (zh)
HU (1) HUE039133T2 (zh)
IL (1) IL232055B (zh)
LT (1) LT2766393T (zh)
MA (1) MA35712B1 (zh)
MX (1) MX2014004022A (zh)
PE (1) PE20141562A1 (zh)
PL (1) PL2766393T3 (zh)
PT (1) PT2766393T (zh)
RS (1) RS57645B1 (zh)
SG (1) SG11201401477XA (zh)
SI (1) SI2766393T1 (zh)
TR (1) TR201811270T4 (zh)
TW (1) TW201321414A (zh)
WO (1) WO2013055998A1 (zh)
ZA (1) ZA201402172B (zh)

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CA2944712A1 (en) 2014-05-01 2015-11-05 Genentech, Inc. Anti-factor d antibody variants and uses thereof
EP3218403B1 (en) 2014-11-10 2020-05-13 F.Hoffmann-La Roche Ag Anti-interleukin-33 antibodies and uses thereof
WO2017075173A2 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibodies and conjugates
CN108472382A (zh) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 抗-因子d抗体变体缀合物及其用途
CN108602881A (zh) 2015-10-30 2018-09-28 豪夫迈·罗氏有限公司 抗-因子d抗体制剂
MX2018004509A (es) * 2015-10-30 2018-08-01 Genentech Inc Anticuerpos anti-htra1 y metodos de uso de los mismos.
WO2017222915A1 (en) 2016-06-21 2017-12-28 Inception 4, Inc. Heterocyclic prolinamide derivatives
EP3472151A4 (en) 2016-06-21 2020-03-04 Orion Ophthalmology LLC CARBOCYCLIC PROLINAMIDE DERIVATIVES
JP2018096930A (ja) * 2016-12-16 2018-06-21 公益財団法人ヒューマンサイエンス振興財団 加齢黄斑変性の診断マーカー、診断キット、診断補助方法、及び、発症リスク判定方法
SI3561056T1 (sl) * 2016-12-22 2024-02-29 Daiichi Sankyo Company, Limited Peptid za zdravljenje starostne degeneracije makule
US11453718B2 (en) 2017-03-27 2022-09-27 The Schepens Eye Research Institute, Inc. NOTCH3 agonist compositions and methods for treating small vessel diseases
EP3729095A1 (en) * 2017-12-21 2020-10-28 F. Hoffmann-La Roche AG Companion diagnostic for htra1 rna antagonists
TW202015718A (zh) * 2018-06-21 2020-05-01 日商第一三共股份有限公司 視網膜色素變性治療用胜肽
WO2020102680A1 (en) * 2018-11-16 2020-05-22 Gemini Therapeutics Inc. Antibody-based therapeutics for targeting htra1 and methods of use
WO2020109343A1 (en) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Combination therapy for treatment of macular degeneration
EA202191783A1 (ru) * 2018-12-24 2021-11-16 Вистерра, Инк. Способы определения эпитопов и паратопов
CN113966401A (zh) 2019-04-10 2022-01-21 犹他大学研究基金会 用于治疗amd的htra1调节
CR20220461A (es) 2020-03-13 2022-10-21 Genentech Inc Anticuerpos anti-interleucina-33 y usos de estos
WO2022031680A1 (en) * 2020-08-04 2022-02-10 Exelixis, Inc. Cd47 binding agents and uses thereof
TW202246351A (zh) * 2021-02-08 2022-12-01 美商恩格姆生物製藥公司 Htra1結合劑及其使用方法

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