SI2766393T1 - Protitelesa Anti-HtrA1 in postopki uporabe - Google Patents

Protitelesa Anti-HtrA1 in postopki uporabe

Info

Publication number
SI2766393T1
SI2766393T1 SI201231378T SI201231378T SI2766393T1 SI 2766393 T1 SI2766393 T1 SI 2766393T1 SI 201231378 T SI201231378 T SI 201231378T SI 201231378 T SI201231378 T SI 201231378T SI 2766393 T1 SI2766393 T1 SI 2766393T1
Authority
SI
Slovenia
Prior art keywords
methods
htra1 antibodies
htra1
antibodies
Prior art date
Application number
SI201231378T
Other languages
English (en)
Inventor
Yan Wu
Lookeren-Campagne Menno Van
Daniel Kirchhofer
Michael Terry Lipari
Jr. Kenneth J. Katschke
Paul M. Moran
Scott Stawicki
Wei-Ching Liang
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2766393T1 publication Critical patent/SI2766393T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
SI201231378T 2011-10-14 2012-10-12 Protitelesa Anti-HtrA1 in postopki uporabe SI2766393T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161547649P 2011-10-14 2011-10-14
EP12840084.3A EP2766393B1 (en) 2011-10-14 2012-10-12 ANTI-HtrA1 ANTIBODIES AND METHODS OF USE
PCT/US2012/059878 WO2013055998A1 (en) 2011-10-14 2012-10-12 ANTI-HtrA1 ANTIBODIES AND METHODS OF USE

Publications (1)

Publication Number Publication Date
SI2766393T1 true SI2766393T1 (sl) 2018-10-30

Family

ID=48082468

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231378T SI2766393T1 (sl) 2011-10-14 2012-10-12 Protitelesa Anti-HtrA1 in postopki uporabe

Country Status (32)

Country Link
US (3) US9738727B2 (sl)
EP (2) EP2766393B1 (sl)
JP (2) JP6532678B2 (sl)
KR (2) KR102102862B1 (sl)
CN (2) CN108373506A (sl)
AR (1) AR088322A1 (sl)
AU (2) AU2012322618A1 (sl)
BR (1) BR112014008862A2 (sl)
CA (1) CA2850032C (sl)
CL (1) CL2014000888A1 (sl)
CO (1) CO7020870A2 (sl)
CR (1) CR20140212A (sl)
DK (1) DK2766393T3 (sl)
EA (1) EA201490778A1 (sl)
ES (1) ES2687951T3 (sl)
HK (1) HK1255608A1 (sl)
HR (1) HRP20181457T1 (sl)
HU (1) HUE039133T2 (sl)
IL (1) IL232055B (sl)
LT (1) LT2766393T (sl)
MA (1) MA35712B1 (sl)
MX (1) MX2014004022A (sl)
PE (1) PE20141562A1 (sl)
PL (1) PL2766393T3 (sl)
PT (1) PT2766393T (sl)
RS (1) RS57645B1 (sl)
SG (1) SG11201401477XA (sl)
SI (1) SI2766393T1 (sl)
TR (1) TR201811270T4 (sl)
TW (1) TW201321414A (sl)
WO (1) WO2013055998A1 (sl)
ZA (1) ZA201402172B (sl)

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BR112016025312A2 (pt) 2014-05-01 2017-10-17 Genentech Inc variantes de anticorpo, anticorpo anti-fator d, formulação farmacêutica, dispositivo de distribuição, utilização da formulação e de uma composição, composição e método de tratamento de uma desordem
CR20170240A (es) 2014-11-10 2018-04-03 Genentech Inc Anticuerpos anti-interleucina-33 y sus usos
EP3368074A2 (en) 2015-10-30 2018-09-05 Hoffmann-La Roche AG Anti-factor d antibodies and conjugates
HUE054093T2 (hu) * 2015-10-30 2021-08-30 Hoffmann La Roche Anti-HtrA1 antitestek és azok alkalmazási eljárásai
EP3368090A1 (en) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Anti-factor d antibody variant conjugates and uses thereof
WO2017075259A1 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody formulations
WO2017222915A1 (en) 2016-06-21 2017-12-28 Inception 4, Inc. Heterocyclic prolinamide derivatives
US10526315B2 (en) 2016-06-21 2020-01-07 Orion Ophthalmology LLC Carbocyclic prolinamide derivatives
JP2018096930A (ja) * 2016-12-16 2018-06-21 公益財団法人ヒューマンサイエンス振興財団 加齢黄斑変性の診断マーカー、診断キット、診断補助方法、及び、発症リスク判定方法
AU2017384348B2 (en) * 2016-12-22 2024-03-07 Daiichi Sankyo Company, Limited Peptide for treating age-related macular degeneration
US11453718B2 (en) 2017-03-27 2022-09-27 The Schepens Eye Research Institute, Inc. NOTCH3 agonist compositions and methods for treating small vessel diseases
US20200378970A1 (en) * 2017-12-21 2020-12-03 Hoffmann-La Roche Inc. Companion diagnostic for htra1 rna antagonists
TW202015718A (zh) 2018-06-21 2020-05-01 日商第一三共股份有限公司 視網膜色素變性治療用胜肽
WO2020102680A1 (en) * 2018-11-16 2020-05-22 Gemini Therapeutics Inc. Antibody-based therapeutics for targeting htra1 and methods of use
WO2020109343A1 (en) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Combination therapy for treatment of macular degeneration
CA3124359A1 (en) * 2018-12-24 2020-07-02 Visterra, Inc. Methods for identifying epitopes and paratopes
US20230165976A1 (en) 2019-04-10 2023-06-01 University Of Utah Research Foundation Htra1 modulation for treatment of amd
WO2021183849A1 (en) 2020-03-13 2021-09-16 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
CN116507639A (zh) * 2020-08-04 2023-07-28 埃克塞里艾克西斯公司 Cd47结合剂及其用途
TW202246351A (zh) * 2021-02-08 2022-12-01 美商恩格姆生物製藥公司 Htra1結合劑及其使用方法

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