LT2571510T - Biosintetiniai prolino (alanino) statistinės spiralės polipeptidai ir jų panaudojimas - Google Patents

Biosintetiniai prolino (alanino) statistinės spiralės polipeptidai ir jų panaudojimas

Info

Publication number
LT2571510T
LT2571510T LTEP11725656.0T LT11725656T LT2571510T LT 2571510 T LT2571510 T LT 2571510T LT 11725656 T LT11725656 T LT 11725656T LT 2571510 T LT2571510 T LT 2571510T
Authority
LT
Lithuania
Prior art keywords
random coil
coil polypeptides
biosynthetic
proline
alanine random
Prior art date
Application number
LTEP11725656.0T
Other languages
English (en)
Lithuanian (lt)
Inventor
Arne Skerra
Uli Binder
Martin Schlapschy
Original Assignee
Xl-Protein Gmbh
Technische Universität München
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xl-Protein Gmbh, Technische Universität München filed Critical Xl-Protein Gmbh
Publication of LT2571510T publication Critical patent/LT2571510T/lt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C07K14/615—Extraction from natural sources
    • C—CHEMISTRY; METALLURGY
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
LTEP11725656.0T 2010-05-21 2011-05-20 Biosintetiniai prolino (alanino) statistinės spiralės polipeptidai ir jų panaudojimas LT2571510T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10163564 2010-05-21
US201061428016P 2010-12-29 2010-12-29
PCT/EP2011/058307 WO2011144756A1 (en) 2010-05-21 2011-05-20 Biosynthetic proline/alanine random coil polypeptides and their uses

Publications (1)

Publication Number Publication Date
LT2571510T true LT2571510T (lt) 2018-11-12

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LTEP11725656.0T LT2571510T (lt) 2010-05-21 2011-05-20 Biosintetiniai prolino (alanino) statistinės spiralės polipeptidai ir jų panaudojimas

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US (3) US9221882B2 (enExample)
EP (2) EP2571510B1 (enExample)
JP (2) JP5828889B2 (enExample)
KR (1) KR101872541B1 (enExample)
CN (2) CN102883734B (enExample)
AU (1) AU2011254564B2 (enExample)
BR (1) BR112012029577B1 (enExample)
CA (1) CA2794614C (enExample)
DK (1) DK2571510T3 (enExample)
EA (1) EA024755B1 (enExample)
ES (1) ES2691642T3 (enExample)
LT (1) LT2571510T (enExample)
MX (2) MX357674B (enExample)
NZ (1) NZ602522A (enExample)
PL (1) PL2571510T3 (enExample)
SG (1) SG185440A1 (enExample)
SI (1) SI2571510T1 (enExample)
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CA3004716C (en) 2008-04-29 2022-04-12 Ascendis Pharma Endocrinology Division A/S Pegylated recombinant human growth hormone compounds
SG181648A1 (en) 2009-12-15 2012-07-30 Ascendis Pharma As Dry growth hormone composition transiently linked to a polymer carrier
DK2571510T3 (en) 2010-05-21 2018-11-19 Xl Protein Gmbh BIOSYNTHETIC PROLIN / ALANIN-RANDOM COIL POLYPEPTIDES AND THEIR APPLICATIONS
US20140323402A1 (en) * 2011-08-12 2014-10-30 Ascendis Phama A/S Protein Carrier-Linked Prodrugs
CN107496932A (zh) * 2012-02-27 2017-12-22 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
CN104411324A (zh) 2012-04-04 2015-03-11 哈洛齐梅公司 使用抗透明质酸剂和肿瘤靶向紫杉烷的组合疗法
WO2014114660A1 (en) 2013-01-22 2014-07-31 Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion
JP6259207B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 エラスチン産生促進剤
JP6259209B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 コラーゲン産生促進剤
JP6259208B2 (ja) * 2013-06-17 2018-01-10 雪印メグミルク株式会社 ヒアルロン酸産生促進剤
US20160296600A1 (en) 2013-11-11 2016-10-13 Ascendis Pharma Relaxin Division A/S Relaxin Prodrugs
US9618507B2 (en) 2014-02-24 2017-04-11 Betanien Hospital Methods of treating rheumatoid arthritis
EP3113792B1 (en) 2014-03-05 2018-12-05 Merz Pharma GmbH & Co. KGaA Novel recombinant clostridial neurotoxins with increased duration of effect
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