BR112023018802A2 - Uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamação - Google Patents
Uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamaçãoInfo
- Publication number
- BR112023018802A2 BR112023018802A2 BR112023018802A BR112023018802A BR112023018802A2 BR 112023018802 A2 BR112023018802 A2 BR 112023018802A2 BR 112023018802 A BR112023018802 A BR 112023018802A BR 112023018802 A BR112023018802 A BR 112023018802A BR 112023018802 A2 BR112023018802 A2 BR 112023018802A2
- Authority
- BR
- Brazil
- Prior art keywords
- inflammation
- long
- growth hormone
- treatment
- acting growth
- Prior art date
Links
- 102000018997 Growth Hormone Human genes 0.000 title abstract 4
- 108010051696 Growth Hormone Proteins 0.000 title abstract 4
- 239000000122 growth hormone Substances 0.000 title abstract 4
- 206010061218 Inflammation Diseases 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000004054 inflammatory process Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamação. a presente invenção refere-se a um hormônio de crescimento de ação prolongada (gh) para uso no tratamento de uma doença induzida por inflamação.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP21166699 | 2021-04-01 | ||
PCT/EP2022/058584 WO2022207798A1 (en) | 2021-04-01 | 2022-03-31 | Use of long-acting growth hormone for treating inflammation-induced diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023018802A2 true BR112023018802A2 (pt) | 2023-10-31 |
Family
ID=75362497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023018802A BR112023018802A2 (pt) | 2021-04-01 | 2022-03-31 | Uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamação |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP4314035A1 (pt) |
JP (1) | JP2024514095A (pt) |
KR (1) | KR20230164709A (pt) |
CN (1) | CN117396497A (pt) |
AU (1) | AU2022246997A1 (pt) |
BR (1) | BR112023018802A2 (pt) |
CA (1) | CA3212417A1 (pt) |
IL (1) | IL307192A (pt) |
MX (1) | MX2023011059A (pt) |
WO (1) | WO2022207798A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115845032A (zh) * | 2022-10-28 | 2023-03-28 | 深圳科兴药业有限公司 | 生长激素fc融合蛋白注射液及其用途 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6624142B2 (en) | 1997-12-30 | 2003-09-23 | Enzon, Inc. | Trimethyl lock based tetrapartate prodrugs |
US7332164B2 (en) | 2003-03-21 | 2008-02-19 | Enzon Pharmaceuticals, Inc. | Heterobifunctional polymeric bioconjugates |
DK1620118T3 (da) | 2003-04-08 | 2014-09-29 | Yeda Res & Dev | Reversible pegylerede lægemidler |
US7690003B2 (en) | 2003-08-29 | 2010-03-30 | Fuller Jeffrey C | System and method for increasing data throughput using thread scheduling |
TW200526254A (en) | 2003-09-19 | 2005-08-16 | Novo Nordisk As | Novel GLP-1 derivatives |
CA2786794C (en) | 2004-03-23 | 2017-09-12 | Complex Biosystems Gmbh | Aromatic polymeric cascade prodrug linker reagent |
US7968085B2 (en) | 2004-07-05 | 2011-06-28 | Ascendis Pharma A/S | Hydrogel formulations |
US8450269B2 (en) | 2006-02-03 | 2013-05-28 | Prolor Biotech Ltd. | Long-acting growth hormone and methods of producing same |
CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
SI2173890T1 (sl) | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
CA2693616A1 (en) | 2007-07-11 | 2009-01-15 | Enzon Pharmaceuticals, Inc. | Polymeric drug delivery system containing a multi-substituted aromatic moiety |
US8906847B2 (en) | 2008-02-01 | 2014-12-09 | Ascendis Pharma A/S | Prodrug comprising a drug linker conjugate |
JP2011520983A (ja) | 2008-05-23 | 2011-07-21 | エンゾン ファーマシューティカルズ,インコーポレーテッド | オリゴヌクレオチドの送達のための細胞内遊離可能ジスルフィドリンカーを含有するポリマーシステム |
MX362028B (es) | 2009-02-03 | 2019-01-04 | Amunix Pharmaceuticals Inc | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. |
RU2554854C9 (ru) | 2009-07-31 | 2017-02-03 | Асцендис Фарма Ас | Биоразлагаемые нерастворимые в воде гидрогели на основе полиэтиленгликоля |
CN102724967A (zh) | 2009-12-31 | 2012-10-10 | 安龙制药公司 | 包括可释放的脲连接体的含芳香胺化合物的聚合缀合物 |
EP2552967A4 (en) | 2010-04-02 | 2014-10-08 | Amunix Operating Inc | BINDING FUSION PROTEINS, BINDING FUSION PROTEIN MEDICINAL CONJUGATES, XTEN MEDICAMENT CONJUGATES, AND METHOD FOR THEIR PREPARATION AND USE |
US8754190B2 (en) | 2010-05-05 | 2014-06-17 | Prolynx Llc | Controlled release from macromolecular conjugates |
US8946405B2 (en) | 2010-05-05 | 2015-02-03 | Prolynx Llc | Controlled release from solid supports |
EA024755B1 (ru) | 2010-05-21 | 2016-10-31 | ИксЭль-ПРОТЕИН ГМБХ | Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения |
AU2012296950B2 (en) | 2011-08-12 | 2016-09-22 | Ascendis Pharma A/S | Polymeric hyperbranched carrier-linked prodrugs |
US20140323402A1 (en) | 2011-08-12 | 2014-10-30 | Ascendis Phama A/S | Protein Carrier-Linked Prodrugs |
US20140296257A1 (en) | 2011-08-12 | 2014-10-02 | Ascendis Pharma A/S | High-Loading Water-Soluable Carrier-Linked Prodrugs |
KR102226702B1 (ko) | 2011-09-07 | 2021-03-11 | 프로린크스 엘엘시 | 생분해성 교차결합을 가지는 하이드로젤 |
WO2013036857A1 (en) | 2011-09-07 | 2013-03-14 | Prolynx Llc | Sulfone linkers |
WO2014056926A1 (en) | 2012-10-11 | 2014-04-17 | Ascendis Pharma A/S | Hydrogel prodrugs |
EP2908845A1 (en) | 2012-10-17 | 2015-08-26 | Novo Nordisk Health Care AG | Fatty acid acylated amino acids for growth hormone delivery |
CA2955569C (en) | 2014-08-06 | 2023-02-14 | Ascendis Pharma A/S | Prodrugs comprising an aminoalkyl glycine linker |
CA2968282A1 (en) | 2014-11-18 | 2016-05-26 | Thomas Kurpiers | Polymeric hgh prodrugs |
AU2018240375C1 (en) | 2017-03-22 | 2024-02-01 | Ascendis Pharma A/S | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods |
EP3856257A1 (en) | 2018-09-26 | 2021-08-04 | Ascendis Pharma A/S | Degradable hyaluronic acid hydrogels |
SG11202101971XA (en) | 2018-09-26 | 2021-03-30 | Ascendis Pharma As | Novel hydrogel conjugates |
BR112021020023A2 (pt) | 2019-04-05 | 2021-12-07 | Prolynx Llc | Ligantes de conjugação melhorados |
WO2021030196A1 (en) | 2019-08-09 | 2021-02-18 | Phasebio Pharmaceuticals, Inc. | Elp fusion proteins comprising parathyroid hormone for controlled and sustained release |
-
2022
- 2022-03-31 AU AU2022246997A patent/AU2022246997A1/en active Pending
- 2022-03-31 JP JP2023560478A patent/JP2024514095A/ja active Pending
- 2022-03-31 MX MX2023011059A patent/MX2023011059A/es unknown
- 2022-03-31 BR BR112023018802A patent/BR112023018802A2/pt unknown
- 2022-03-31 WO PCT/EP2022/058584 patent/WO2022207798A1/en active Application Filing
- 2022-03-31 CN CN202280038557.7A patent/CN117396497A/zh active Pending
- 2022-03-31 CA CA3212417A patent/CA3212417A1/en active Pending
- 2022-03-31 KR KR1020237037345A patent/KR20230164709A/ko unknown
- 2022-03-31 EP EP22713687.6A patent/EP4314035A1/en active Pending
- 2022-03-31 IL IL307192A patent/IL307192A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL307192A (en) | 2023-11-01 |
AU2022246997A1 (en) | 2023-09-28 |
EP4314035A1 (en) | 2024-02-07 |
WO2022207798A1 (en) | 2022-10-06 |
KR20230164709A (ko) | 2023-12-04 |
MX2023011059A (es) | 2023-09-29 |
CA3212417A1 (en) | 2022-10-06 |
CN117396497A (zh) | 2024-01-12 |
JP2024514095A (ja) | 2024-03-28 |
AU2022246997A9 (en) | 2024-01-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112017023233A2 (pt) | métodos para tratamento de câncer | |
CL2019000221A1 (es) | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1. | |
BRPI0713755A8 (pt) | composto ou um sal ou solvato do mesmo, uso do composto ou um sal ou salvato do mesmo, composição farmacêutica,e, processo para a preparação de um composto ou um sal ou solvato do mesmo | |
BR112015021371A2 (pt) | uso de agonistas de receptor de formil peptídeo 2 para tratar doenças inflamatórias oculares | |
PH12015502691A1 (en) | Use of high dose pridopidine for treating huntington's disease | |
BRPI0511569A (pt) | composições e métodos para o tratamento de distúrbio disfórico pré-menstrual | |
AR059982A1 (es) | Terapia tumoral con un anticuerpo contra el factor de crecimiento endotelial vascular y un anticuerpo contra el receptor del factor de crecimiento epitelial tipo 2 humano | |
CO2021006672A2 (es) | Moduladores de nlrp3 | |
GT200500028A (es) | Oxadiazolonas, procedimientos para su preparacion y su uso como productos farmaceuticos. | |
BR112023018802A2 (pt) | Uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamação | |
CO2019011546A2 (es) | Compuestos y métodos para el tratamiento de enfermedades parasitarias | |
BR112015022469A2 (pt) | peptídeo ou análogo seu, composição, método para melhorar um sinal ou sintoma, método para estimular o crescimento de células, método para produção de uma população de células, método para aumentar o número de células, método para redução em um indivíduo diabético da tolerância à glicose debilitada, método para a promoção de neuroproteção ou regeneração nervosa, método para a promoção da regeneração, método para a inibição de inflamação, composição farmacêutica e uso de um peptídeo ou análogo seu | |
AR104755A1 (es) | Método para el tratamiento de enfermedad neurológica | |
EA202091604A1 (ru) | Ингибирование ионного канала a1 с транзиторным рецепторным потенциалом | |
CL2022000005A1 (es) | Inhibidores de monoacilglicerol lipasa (magl) heterocíclicos | |
CO2023018231A2 (es) | Restos de administración terapéutica novedosos y usos de estos | |
CL2020002177A1 (es) | Indazol-3-carboxamidas sustituidas con 5-heteroarilo y preparación y uso de las mismas | |
CL2021002483A1 (es) | Compuestos y composiciones como moduladores de la señalización tlr | |
ECSP23077322A (es) | Derivados de fósforo como nuevos inhibidores de sos1 | |
CL2023001596A1 (es) | Composiciones y métodos para el tratamiento de enfermedades oculares | |
CL2023000853A1 (es) | Compuestos y composiciones como moduladores de señalización tlr | |
CO2022013429A2 (es) | Formulaciones de liberación controlada que comprenden drotaverina o sal de la misma | |
BR112017021583A2 (pt) | métodos para o tratamento de transtornos inflamatórios | |
MX2021011269A (es) | Tratamiento de enfermedades y trastornos asociados a las mitocondrias, incluyendo los sintomas de los mismos usando pridopidina. | |
ZA202001568B (en) | Methods and compositions for treating chronic lung diseases |