KR870011252A - 히아루론산의 신규 생산방법 및 이를 생산하는 박테리아 균주 그리고 히아루론산을 함유하는 화장품 - Google Patents

히아루론산의 신규 생산방법 및 이를 생산하는 박테리아 균주 그리고 히아루론산을 함유하는 화장품 Download PDF

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KR870011252A
KR870011252A KR870003999A KR870003999A KR870011252A KR 870011252 A KR870011252 A KR 870011252A KR 870003999 A KR870003999 A KR 870003999A KR 870003999 A KR870003999 A KR 870003999A KR 870011252 A KR870011252 A KR 870011252A
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hyaluronic acid
streptococcus
negative
jupitemicus
resistance
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KR870003999A
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KR960005736B1 (ko
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히데오 호소야
마사유끼 기무라
히로시 엔도
요시오 히라끼
쇼지 야마모또
사또시 요시까와
히데다까 오미네
고지 미야자와
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마쯔조노 히사미
가부시끼가이샤 야쿠르트혼샤
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Priority claimed from JP61099447A external-priority patent/JPS62257382A/ja
Priority claimed from JP61099446A external-priority patent/JPS62257393A/ja
Priority claimed from JP61302922A external-priority patent/JPS63156707A/ja
Priority claimed from JP62064994A external-priority patent/JPH075448B2/ja
Application filed by 마쯔조노 히사미, 가부시끼가이샤 야쿠르트혼샤 filed Critical 마쯔조노 히사미
Publication of KR870011252A publication Critical patent/KR870011252A/ko
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Publication of KR960005736B1 publication Critical patent/KR960005736B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract

내용 없음

Description

히아루론산의 신규 생산방법 및 이를 생산하는 박테리아 균주 그리고 히아루론산을 함유하는 화장품
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 실시예 2의 히아루론산 상산 박테리아의 배양과정을 나타내는 도면이다.
제2도는 실시예 3의 배양과정을 나타내는 도면이다.
제3도는 실시예 2에서 얻어진 고분자 히아루론산의 IR흡수 스펙트럼을 나타내는 도면이다.

Claims (10)

  1. 히아루론산 생성능력을 가지며, 히아루로니다제 비생성이며, 비용혈성을 나타내는 스트렙토코쿠스에 속하는 균주를 배지에서 배양하고 생성배양으로부터 히아루론산을 수집하는 것을 특징으로 하는 히아루론산의 생산방법.
  2. 제1항에 있어서, 스트렙토코쿠스에 소가는 균주가 스트렙토코쿠스 주에피데미쿠스임을 특징으로 하는 방법.
  3. 제2항에 있어서, 스트렙토코쿠스 주에피데미쿠스가 스트렙토코쿠스 주에피데미쿠스YIT 2030(FERM BP-1305)임을 특징으로 하는 방법.
  4. 히아루론산 생성능력을 가지며, 히아루로니다제 비생성이며 비용혈성을 나타냄을 특징으로하는 스트렙토코쿠스 주에피데미쿠스
  5. 제4항에 있어서, 후술하는 세균학적 특성을 나타냄을 특징으로 하는 스트렙토코쿠스 주에피데미쿠스:
    (a) 그람 균주;양성
    (b) 10°C 에서의 성장:음성
    (c) 45°C 에서의 성장:음성
    (d) 0.1% 메틸렌 블루:음성
    (e) 6.5% 식염수 내성:음성
    (f) 40% 담즙내성:음성
    (g)바시트라신 내성:음성
    (h)pH9.6에서의 내성:음성
    (i)60°C에서 30분 동안 처리시 내성:음성
    (j)젤라틴 액화성:음성
    (k)전분 분해성:음성
    (l)나트륨 히퓨레이트 분해성:음성
    (m)에스쿨린 분해성:약한 양성
    (n)아르기닌 분해성:앵상
    (o)당 발효성:
    글루코스, 간락토스, 자당, 유당, 맥아당, 소르비톨과 살리신:양성
    글리세린, 만니톨, 트레할로스와 아라비노스:음성
  6. 제4항 또는 제5항에 있어서, 스트렙토코쿠스 주에피데미쿠스가 스트렙토코쿠스 주에피데미쿠스 YIT 2030(FERMBP-1305)임을 특징으로 함.
  7. 분자량 2,000,000이상의 히아루론산 또는 그의 염을 함유함을 특징으로 하는 화장품.
  8. 제7항에 있어서, 박테리아에 의해 생성되는 분자량 2,000,000이상의 히아루론산을 함유함을 특징으로하는 화장품.
  9. 제7항에 있어서, 분자량 2,000,000이상의 히아루론산을 생성하고 박테리아가 스트렙토코쿠스 주에피데미쿠스임을 특징으로 하는 화장품.
  10. 제8항 또는 제9항에 있어서, 분자량 2.000.000이상의 히아루론산을 생성하는 박테리아가 스트렙토코쿠스 주에피데미쿠스 YIT 2030(FERM BP-1305)임을 특징으로 하는 화장품.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870003999A 1986-05-01 1987-04-25 히아루론산의 신규 생산방법 KR960005736B1 (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
JP99447 1986-05-01
JP99446/1986 1986-05-01
JP99447/1986 1986-05-01
JP61099447A JPS62257382A (ja) 1986-05-01 1986-05-01 新規なストレプトコツカス・ズ−エピデミカス
JP99446 1986-05-01
JP61099446A JPS62257393A (ja) 1986-05-01 1986-05-01 ヒアルロン酸の製造方法
JP302922/1986 1986-12-19
JP61302922A JPS63156707A (ja) 1986-12-19 1986-12-19 ヒアルロン酸含有化粧料
JP302922 1986-12-19
JP64994/1987 1987-03-19
JP62064994A JPH075448B2 (ja) 1987-03-19 1987-03-19 化粧料

Publications (2)

Publication Number Publication Date
KR870011252A true KR870011252A (ko) 1987-12-22
KR960005736B1 KR960005736B1 (ko) 1996-05-01

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KR1019870003999A KR960005736B1 (ko) 1986-05-01 1987-04-25 히아루론산의 신규 생산방법

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US (1) US5023175A (ko)
EP (1) EP0244757B1 (ko)
KR (1) KR960005736B1 (ko)
AU (1) AU598809B2 (ko)
CA (1) CA1314508C (ko)
DE (1) DE3750733T2 (ko)

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DE3750733T2 (de) 1995-05-18
AU7196087A (en) 1987-11-05
KR960005736B1 (ko) 1996-05-01
EP0244757A2 (en) 1987-11-11
CA1314508C (en) 1993-03-16
AU598809B2 (en) 1990-07-05
EP0244757A3 (en) 1988-08-24
US5023175A (en) 1991-06-11
EP0244757B1 (en) 1994-11-09
DE3750733D1 (de) 1994-12-15

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