EP0346467A4 - Process for purifying hyaluronic acid - Google Patents

Process for purifying hyaluronic acid

Info

Publication number
EP0346467A4
EP0346467A4 EP19880900592 EP88900592A EP0346467A4 EP 0346467 A4 EP0346467 A4 EP 0346467A4 EP 19880900592 EP19880900592 EP 19880900592 EP 88900592 A EP88900592 A EP 88900592A EP 0346467 A4 EP0346467 A4 EP 0346467A4
Authority
EP
European Patent Office
Prior art keywords
hyaluronic acid
purifying hyaluronic
purifying
purification
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19880900592
Other versions
EP0346467A1 (en
Inventor
Hideki Murata
Michio Shiomi
Shinzo Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority claimed from PCT/JP1987/001044 external-priority patent/WO1989006243A1/en
Publication of EP0346467A1 publication Critical patent/EP0346467A1/en
Publication of EP0346467A4 publication Critical patent/EP0346467A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A process for purifying hyaluronic acid, which comprises using a macroreticular anion-exchange resin in the separation and purification of hyaluronic acid from a solution containing it.
EP19880900592 1987-12-26 1987-12-26 Process for purifying hyaluronic acid Withdrawn EP0346467A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1987/001044 WO1989006243A1 (en) 1986-07-03 1987-12-26 Process for purifying hyaluronic acid

Publications (2)

Publication Number Publication Date
EP0346467A1 EP0346467A1 (en) 1989-12-20
EP0346467A4 true EP0346467A4 (en) 1990-11-28

Family

ID=13902975

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19880900592 Withdrawn EP0346467A4 (en) 1987-12-26 1987-12-26 Process for purifying hyaluronic acid

Country Status (1)

Country Link
EP (1) EP0346467A4 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274984B (en) * 1994-12-09 1997-07-29 Technopharma Sa SOLUTIONS VISCOSIZED WITH SODIUM HYALURONATE FOR USE AS A MASK FLUID IN THERAPEUTIC PHOTOCERATECTOMY BY ACCIMER LASER
KR19980080116A (en) * 1997-03-27 1998-11-25 히라따 다다시 Purification Method of Sodium Hyaluronate
JP5689064B2 (en) * 2008-10-27 2015-03-25 ノバルティス アーゲー Purification method
CN102702385B (en) * 2012-06-15 2014-02-12 山东省花生研究所 Preparation method for extracting chitosan from holotrichia parallela
CN109517012B (en) * 2018-11-13 2020-05-22 华熙生物科技股份有限公司 Preparation method of hyaluronic acid oligosaccharide
CN113558127A (en) * 2021-08-06 2021-10-29 陈奋 Hyaluronic acid coffee soft drink and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244757A2 (en) * 1986-05-01 1987-11-11 Kabushiki Kaisha Yakult Honsha Novel production process of hyaluronic acid and bacterium strain therefor as well as cosmetic composition containing hyaluronic acid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244757A2 (en) * 1986-05-01 1987-11-11 Kabushiki Kaisha Yakult Honsha Novel production process of hyaluronic acid and bacterium strain therefor as well as cosmetic composition containing hyaluronic acid

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOCHIMICA ET BIOPHYSICA ACTA, vol. 24, 1957, pages 397-400, Amsterdam, NL; J.A. CIFONELLI et al.: "The purification of hyaluronic acid by the use of charcoal" *
See also references of WO8906243A1 *

Also Published As

Publication number Publication date
EP0346467A1 (en) 1989-12-20

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Legal Events

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