KR20200120627A - 인지증 검출을 위한 키트 또는 디바이스 및 방법 - Google Patents

인지증 검출을 위한 키트 또는 디바이스 및 방법 Download PDF

Info

Publication number
KR20200120627A
KR20200120627A KR1020207022584A KR20207022584A KR20200120627A KR 20200120627 A KR20200120627 A KR 20200120627A KR 1020207022584 A KR1020207022584 A KR 1020207022584A KR 20207022584 A KR20207022584 A KR 20207022584A KR 20200120627 A KR20200120627 A KR 20200120627A
Authority
KR
South Korea
Prior art keywords
mir
hsa
nucleotide sequence
polynucleotide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020207022584A
Other languages
English (en)
Korean (ko)
Inventor
카나 스즈키
마키코 요시모토
준페이 카와우치
히로코 수도
유호 키다
사토코 코조노
사토시 콘도우
슌페이 니이다
šœ페이 니이다
유야 아사노미
다이치 시게미즈
타카시 사쿠라이
Original Assignee
도레이 카부시키가이샤
고꾸리쯔 켄큐카이하츠호진 고꾸리쯔 장수의료 연구센터
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 도레이 카부시키가이샤, 고꾸리쯔 켄큐카이하츠호진 고꾸리쯔 장수의료 연구센터 filed Critical 도레이 카부시키가이샤
Publication of KR20200120627A publication Critical patent/KR20200120627A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020207022584A 2018-02-13 2019-02-12 인지증 검출을 위한 키트 또는 디바이스 및 방법 Withdrawn KR20200120627A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2018023283 2018-02-13
JPJP-P-2018-023283 2018-02-13
JPJP-P-2018-085652 2018-04-26
JP2018085652 2018-04-26
JPJP-P-2018-138487 2018-07-24
JP2018138487 2018-07-24
PCT/JP2019/004832 WO2019159884A1 (ja) 2018-02-13 2019-02-12 認知症の検出のためのキット又はデバイス及び方法

Publications (1)

Publication Number Publication Date
KR20200120627A true KR20200120627A (ko) 2020-10-21

Family

ID=67619057

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207022584A Withdrawn KR20200120627A (ko) 2018-02-13 2019-02-12 인지증 검출을 위한 키트 또는 디바이스 및 방법

Country Status (7)

Country Link
US (2) US12529104B2 (https=)
EP (4) EP4498086A3 (https=)
JP (3) JP7414237B2 (https=)
KR (1) KR20200120627A (https=)
CN (1) CN111742060A (https=)
CA (1) CA3091211A1 (https=)
WO (1) WO2019159884A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230121467A (ko) * 2022-02-11 2023-08-18 광주과학기술원 알츠하이머병 진단을 위한 miRNA 바이오마커

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12522827B2 (en) 2016-03-02 2026-01-13 The Board Of Trustees Of The Leland Stanford Junior University Pan-genotypic agents against influenza virus and methods of using the same
CN110511994B (zh) * 2019-09-09 2023-05-26 中南大学湘雅二医院 miRNA-4769-3p及其同源物的应用
CN111218504A (zh) * 2020-01-17 2020-06-02 中国辐射防护研究院 hsa-miR-320d作为辐射暴露诊断的分子标志物的用途
EP4103713A4 (en) * 2020-02-14 2024-03-20 The Board of Trustees of the Leland Stanford Junior University PAN-GENOTYPICAL AGENTS AGAINST RESPIRATORY VIRUSES AND THEIR METHODS OF USE
WO2021201092A1 (ja) 2020-03-31 2021-10-07 東レ株式会社 海馬萎縮を検出するためのキット又はデバイス及び方法
CN114051536A (zh) * 2020-06-12 2022-02-15 国际宇宙医疗株式会社 利用血液中rna的covid-19重症化预测方法
KR102476525B1 (ko) * 2021-02-24 2022-12-13 한국생명공학연구원 체액 검사 기반 퇴행성 뇌질환 진단 및 모니터링 기술
CN114214363B (zh) * 2021-12-03 2024-04-19 浙江大学 一种抗间充质干细胞衰老修饰方法及其应用
CN114015769A (zh) * 2021-12-14 2022-02-08 上海市生物医药技术研究院 银屑病关节炎的诊断标记物及其用途
CN114822850A (zh) * 2022-05-11 2022-07-29 杭州青果医疗科技有限责任公司 预测痴呆症或轻度认知障碍的系统
CN115927578B (zh) * 2022-07-13 2025-12-02 深圳市拾方杰科技有限公司 一种用于自体动静脉内瘘血栓早期预警和诊断的分子标志物及其应用
CN120204406B (zh) * 2025-05-28 2025-08-22 中南大学 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂
CN121466122B (zh) * 2026-01-09 2026-03-20 云南云科生物技术研究院 miR-6809-5p抑制剂的应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130184331A1 (en) 2010-09-13 2013-07-18 Snu R&Db Foundation Treatment of neurodegenerative diseases by targeting mirna
US20140120545A1 (en) 2011-04-18 2014-05-01 Diamir, Llc METHODS OF USING miRNA FROM BODILY FLUIDS FOR EARLY DETECTION AND MONITORING OF MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD)
US20140206777A1 (en) 2011-08-16 2014-07-24 Rosetta Genomics Ltd. Methods and compositions for diagnosis of alzheimer's disease
US20170002348A1 (en) 2013-07-11 2017-01-05 The Trustees Of Columbia University In The City Of New York Micrornas that silence tau expression
WO2017059094A2 (en) 2015-09-29 2017-04-06 Adi Mashiach System and method for detection of disease in bodily fluids
WO2017084770A1 (en) 2015-11-20 2017-05-26 Braindtech S.R.L. Microglial microvesicles contained microrna-based methods for the diagnosis, prognosis and treatment monitoring of neurological, neurodegenerative and inflammation-based diseases
JP2017184642A (ja) 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683036B2 (en) 2003-07-31 2010-03-23 Regulus Therapeutics Inc. Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
EP2610342B1 (en) 2007-09-14 2016-05-04 The Ohio State University Research Foundation MiRNA Expression in Human Peripheral Blood Microvesicles and uses Thereof
RU2639509C2 (ru) 2011-06-27 2017-12-21 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. МикроРНК - БИОМАРКЕРЫ, УКАЗЫВАЮЩИЕ НА БОЛЕЗНЬ АЛЬЦГЕЙМЕРА
CA2838562A1 (en) 2011-08-08 2013-02-14 Eugenia Wang Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof
US20140363469A1 (en) * 2012-01-19 2014-12-11 Alnylam Pharmaceuticals, Inc. Viral attenuation and vaccine production
EP2733219B1 (en) 2012-11-16 2017-09-20 Siemens Aktiengesellschaft Diagnostic miRNA markers for Alzheimer
US20140303025A1 (en) 2013-03-15 2014-10-09 The Translational Genomics Research Institute Methods for the diagnosis and prognosis of neurodegenerative diseases
JP2015223165A (ja) * 2014-05-29 2015-12-14 森永製菓株式会社 認知症のバイオマーカー及び認知症の治療薬のスクリーニング方法
KR102511711B1 (ko) * 2014-06-13 2023-03-20 국립연구개발법인 고쿠리츠간켄큐센터 유방암 검출 키트 또는 디바이스 및 검출 방법
CN118813801A (zh) * 2014-06-13 2024-10-22 东丽株式会社 大肠癌的检测试剂盒或装置以及检测方法
SG11201806879SA (en) * 2016-02-24 2018-09-27 Agency Science Tech & Res A simple one-step real-time molecular system for microrna detection
WO2017186719A1 (en) 2016-04-25 2017-11-02 Instytut Biologii Doswiadczalnej Im. Marcelego Nenckiego Polska Akademia Nauk Microrna biomarkers in blood for diagnosis of alzheimer's disease
EP3449009B1 (en) * 2016-04-25 2021-08-18 Instytut Biologii Doswiadczalnej PAN. im. M. Nenckiego Microrna biomarkers in blood for diagnosis of alzheimer's disease
JP2018023283A (ja) 2016-07-19 2018-02-15 鈞 村井 刈払機
US10457940B2 (en) * 2016-09-22 2019-10-29 University Of Massachusetts AAV treatment of Huntington's disease
KR101992539B1 (ko) * 2016-10-21 2019-09-30 서울대학교산학협력단 miRNA 기반의 인지장애 질환 진단용 조성물 및 방법
JP6804947B2 (ja) 2016-11-24 2020-12-23 株式会社東芝 情報取得装置及び情報取得方法
JP6899091B2 (ja) 2017-02-24 2021-07-07 株式会社リコー シート積載装置、給送装置及び画像形成装置
EP3679157B1 (en) * 2017-09-05 2024-12-18 Amoneta Diagnostics Non-coding rnas (ncrna) for the diagnosis of cognitive disorders
GB201812334D0 (en) * 2018-07-27 2018-09-12 Univ Exeter Compositions and uses thereof
EP3891295B1 (en) * 2018-12-04 2026-03-25 La Trobe University Methods of diagnosing a disease state
WO2021201092A1 (ja) * 2020-03-31 2021-10-07 東レ株式会社 海馬萎縮を検出するためのキット又はデバイス及び方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130184331A1 (en) 2010-09-13 2013-07-18 Snu R&Db Foundation Treatment of neurodegenerative diseases by targeting mirna
US20140120545A1 (en) 2011-04-18 2014-05-01 Diamir, Llc METHODS OF USING miRNA FROM BODILY FLUIDS FOR EARLY DETECTION AND MONITORING OF MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD)
US20140206777A1 (en) 2011-08-16 2014-07-24 Rosetta Genomics Ltd. Methods and compositions for diagnosis of alzheimer's disease
US20170002348A1 (en) 2013-07-11 2017-01-05 The Trustees Of Columbia University In The City Of New York Micrornas that silence tau expression
WO2017059094A2 (en) 2015-09-29 2017-04-06 Adi Mashiach System and method for detection of disease in bodily fluids
WO2017084770A1 (en) 2015-11-20 2017-05-26 Braindtech S.R.L. Microglial microvesicles contained microrna-based methods for the diagnosis, prognosis and treatment monitoring of neurological, neurodegenerative and inflammation-based diseases
JP2017184642A (ja) 2016-04-01 2017-10-12 株式会社ヘルシーパス 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Alifiya Kapasi et al., Acta Neuropathol, 2017, vol. 134, p.171-186
Siranjeevi N. et al., Oncotarget, 2017 Feb 05, vol. 8, No. 10, p.16122-16143

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230121467A (ko) * 2022-02-11 2023-08-18 광주과학기술원 알츠하이머병 진단을 위한 miRNA 바이오마커

Also Published As

Publication number Publication date
EP4697021A2 (en) 2026-02-18
JP7414237B2 (ja) 2024-01-16
JP2024037978A (ja) 2024-03-19
EP4498086A2 (en) 2025-01-29
EP3754019A4 (en) 2022-02-16
WO2019159884A1 (ja) 2019-08-22
US20260117305A1 (en) 2026-04-30
US12529104B2 (en) 2026-01-20
US20210047691A1 (en) 2021-02-18
EP3754019A1 (en) 2020-12-23
CA3091211A1 (en) 2019-08-22
EP4328587A2 (en) 2024-02-28
EP4328587A3 (en) 2024-06-05
EP3754019B1 (en) 2024-01-31
EP4498086A3 (en) 2025-04-02
JPWO2019159884A1 (ja) 2021-03-11
CN111742060A (zh) 2020-10-02
JP2025186374A (ja) 2025-12-23

Similar Documents

Publication Publication Date Title
US20260117305A1 (en) Kit or device and method for detecting dementia
JP7426046B2 (ja) 胃がんの検出キット又はデバイス及び検出方法
KR102747965B1 (ko) 폐암의 검출을 위한 키트, 디바이스 및 방법
KR102511713B1 (ko) 대장암의 검출 키트 또는 디바이스 및 검출 방법
KR102581671B1 (ko) 식도암의 검출 키트 또는 디바이스 및 검출 방법
KR102581812B1 (ko) 폐암의 검출 키트 또는 디바이스 및 검출 방법
KR102679577B1 (ko) 담도암 검출 키트 또는 디바이스 및 검출 방법
KR20170018411A (ko) 간암의 검출 키트 또는 디바이스 및 검출 방법
KR20170016490A (ko) 전립선암 검출 키트 또는 디바이스 및 검출 방법
KR20210005148A (ko) 방광암의 검출을 위한 키트, 디바이스 및 방법
KR20220160602A (ko) 해마 위축을 검출하기 위한 키트 또는 디바이스 및 방법

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20200804

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20220204

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20240703

Patent event code: PE09021S01D

PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20240829

WITB Written withdrawal of application