CN111742060A - 用于痴呆的检测的试剂盒或器件和方法 - Google Patents

用于痴呆的检测的试剂盒或器件和方法 Download PDF

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Publication number
CN111742060A
CN111742060A CN201980013178.0A CN201980013178A CN111742060A CN 111742060 A CN111742060 A CN 111742060A CN 201980013178 A CN201980013178 A CN 201980013178A CN 111742060 A CN111742060 A CN 111742060A
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China
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mir
polynucleotide
hsa
base sequence
seq
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CN201980013178.0A
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Chinese (zh)
Inventor
铃木佳奈
吉本真纪子
河内淳平
须藤裕子
木田悠步
小园聪子
近藤哲司
新饭田俊平
浅海裕也
重水大智
樱井孝
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National Center for Geriatrics and Gerontology
Toray Industries Inc
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National Center for Geriatrics and Gerontology
Toray Industries Inc
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Publication of CN111742060A publication Critical patent/CN111742060A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201980013178.0A 2018-02-13 2019-02-12 用于痴呆的检测的试剂盒或器件和方法 Pending CN111742060A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2018023283 2018-02-13
JP2018-023283 2018-02-13
JP2018-085652 2018-04-26
JP2018085652 2018-04-26
JP2018-138487 2018-07-24
JP2018138487 2018-07-24
PCT/JP2019/004832 WO2019159884A1 (ja) 2018-02-13 2019-02-12 認知症の検出のためのキット又はデバイス及び方法

Publications (1)

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CN111742060A true CN111742060A (zh) 2020-10-02

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US (2) US12529104B2 (https=)
EP (4) EP4498086A3 (https=)
JP (3) JP7414237B2 (https=)
KR (1) KR20200120627A (https=)
CN (1) CN111742060A (https=)
CA (1) CA3091211A1 (https=)
WO (1) WO2019159884A1 (https=)

Cited By (4)

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CN114015769A (zh) * 2021-12-14 2022-02-08 上海市生物医药技术研究院 银屑病关节炎的诊断标记物及其用途
CN114214363A (zh) * 2021-12-03 2022-03-22 浙江大学 一种抗间充质干细胞衰老修饰方法及其应用
CN120204406A (zh) * 2025-05-28 2025-06-27 中南大学 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂
CN121466122A (zh) * 2026-01-09 2026-02-06 云南云科生物技术研究院 miR-6809-5p抑制剂的应用

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US12522827B2 (en) 2016-03-02 2026-01-13 The Board Of Trustees Of The Leland Stanford Junior University Pan-genotypic agents against influenza virus and methods of using the same
CN110511994B (zh) * 2019-09-09 2023-05-26 中南大学湘雅二医院 miRNA-4769-3p及其同源物的应用
CN111218504A (zh) * 2020-01-17 2020-06-02 中国辐射防护研究院 hsa-miR-320d作为辐射暴露诊断的分子标志物的用途
EP4103713A4 (en) * 2020-02-14 2024-03-20 The Board of Trustees of the Leland Stanford Junior University PAN-GENOTYPICAL AGENTS AGAINST RESPIRATORY VIRUSES AND THEIR METHODS OF USE
WO2021201092A1 (ja) 2020-03-31 2021-10-07 東レ株式会社 海馬萎縮を検出するためのキット又はデバイス及び方法
CN114051536A (zh) * 2020-06-12 2022-02-15 国际宇宙医疗株式会社 利用血液中rna的covid-19重症化预测方法
KR102476525B1 (ko) * 2021-02-24 2022-12-13 한국생명공학연구원 체액 검사 기반 퇴행성 뇌질환 진단 및 모니터링 기술
KR102914388B1 (ko) * 2022-02-11 2026-01-19 광주과학기술원 알츠하이머병 진단을 위한 miRNA 바이오마커
CN114822850A (zh) * 2022-05-11 2022-07-29 杭州青果医疗科技有限责任公司 预测痴呆症或轻度认知障碍的系统
CN115927578B (zh) * 2022-07-13 2025-12-02 深圳市拾方杰科技有限公司 一种用于自体动静脉内瘘血栓早期预警和诊断的分子标志物及其应用

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114214363A (zh) * 2021-12-03 2022-03-22 浙江大学 一种抗间充质干细胞衰老修饰方法及其应用
CN114214363B (zh) * 2021-12-03 2024-04-19 浙江大学 一种抗间充质干细胞衰老修饰方法及其应用
CN114015769A (zh) * 2021-12-14 2022-02-08 上海市生物医药技术研究院 银屑病关节炎的诊断标记物及其用途
CN120204406A (zh) * 2025-05-28 2025-06-27 中南大学 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂
CN120204406B (zh) * 2025-05-28 2025-08-22 中南大学 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂
CN121466122A (zh) * 2026-01-09 2026-02-06 云南云科生物技术研究院 miR-6809-5p抑制剂的应用
CN121466122B (zh) * 2026-01-09 2026-03-20 云南云科生物技术研究院 miR-6809-5p抑制剂的应用

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EP4697021A2 (en) 2026-02-18
JP7414237B2 (ja) 2024-01-16
JP2024037978A (ja) 2024-03-19
EP4498086A2 (en) 2025-01-29
EP3754019A4 (en) 2022-02-16
WO2019159884A1 (ja) 2019-08-22
US20260117305A1 (en) 2026-04-30
US12529104B2 (en) 2026-01-20
US20210047691A1 (en) 2021-02-18
EP3754019A1 (en) 2020-12-23
CA3091211A1 (en) 2019-08-22
EP4328587A2 (en) 2024-02-28
EP4328587A3 (en) 2024-06-05
EP3754019B1 (en) 2024-01-31
KR20200120627A (ko) 2020-10-21
EP4498086A3 (en) 2025-04-02
JPWO2019159884A1 (ja) 2021-03-11
JP2025186374A (ja) 2025-12-23

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