CA3091211A1 - Kit or device and method for detecting dementia - Google Patents
Kit or device and method for detecting dementia Download PDFInfo
- Publication number
- CA3091211A1 CA3091211A1 CA3091211A CA3091211A CA3091211A1 CA 3091211 A1 CA3091211 A1 CA 3091211A1 CA 3091211 A CA3091211 A CA 3091211A CA 3091211 A CA3091211 A CA 3091211A CA 3091211 A1 CA3091211 A1 CA 3091211A1
- Authority
- CA
- Canada
- Prior art keywords
- mir
- hsa
- nucleotide sequence
- polynucleotide
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018023283 | 2018-02-13 | ||
| JP2018-023283 | 2018-02-13 | ||
| JP2018-085652 | 2018-04-26 | ||
| JP2018085652 | 2018-04-26 | ||
| JP2018-138487 | 2018-07-24 | ||
| JP2018138487 | 2018-07-24 | ||
| PCT/JP2019/004832 WO2019159884A1 (ja) | 2018-02-13 | 2019-02-12 | 認知症の検出のためのキット又はデバイス及び方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3091211A1 true CA3091211A1 (en) | 2019-08-22 |
Family
ID=67619057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3091211A Pending CA3091211A1 (en) | 2018-02-13 | 2019-02-12 | Kit or device and method for detecting dementia |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12529104B2 (https=) |
| EP (4) | EP4498086A3 (https=) |
| JP (3) | JP7414237B2 (https=) |
| KR (1) | KR20200120627A (https=) |
| CN (1) | CN111742060A (https=) |
| CA (1) | CA3091211A1 (https=) |
| WO (1) | WO2019159884A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111218504A (zh) * | 2020-01-17 | 2020-06-02 | 中国辐射防护研究院 | hsa-miR-320d作为辐射暴露诊断的分子标志物的用途 |
| CN115927578A (zh) * | 2022-07-13 | 2023-04-07 | 深圳市拾方杰科技有限公司 | 一种用于自体动静脉内瘘血栓早期预警和诊断的分子标志物及其应用 |
| CN120204406A (zh) * | 2025-05-28 | 2025-06-27 | 中南大学 | 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12522827B2 (en) | 2016-03-02 | 2026-01-13 | The Board Of Trustees Of The Leland Stanford Junior University | Pan-genotypic agents against influenza virus and methods of using the same |
| CN110511994B (zh) * | 2019-09-09 | 2023-05-26 | 中南大学湘雅二医院 | miRNA-4769-3p及其同源物的应用 |
| EP4103713A4 (en) * | 2020-02-14 | 2024-03-20 | The Board of Trustees of the Leland Stanford Junior University | PAN-GENOTYPICAL AGENTS AGAINST RESPIRATORY VIRUSES AND THEIR METHODS OF USE |
| WO2021201092A1 (ja) | 2020-03-31 | 2021-10-07 | 東レ株式会社 | 海馬萎縮を検出するためのキット又はデバイス及び方法 |
| CN114051536A (zh) * | 2020-06-12 | 2022-02-15 | 国际宇宙医疗株式会社 | 利用血液中rna的covid-19重症化预测方法 |
| KR102476525B1 (ko) * | 2021-02-24 | 2022-12-13 | 한국생명공학연구원 | 체액 검사 기반 퇴행성 뇌질환 진단 및 모니터링 기술 |
| CN114214363B (zh) * | 2021-12-03 | 2024-04-19 | 浙江大学 | 一种抗间充质干细胞衰老修饰方法及其应用 |
| CN114015769A (zh) * | 2021-12-14 | 2022-02-08 | 上海市生物医药技术研究院 | 银屑病关节炎的诊断标记物及其用途 |
| KR102914388B1 (ko) * | 2022-02-11 | 2026-01-19 | 광주과학기술원 | 알츠하이머병 진단을 위한 miRNA 바이오마커 |
| CN114822850A (zh) * | 2022-05-11 | 2022-07-29 | 杭州青果医疗科技有限责任公司 | 预测痴呆症或轻度认知障碍的系统 |
| CN121466122B (zh) * | 2026-01-09 | 2026-03-20 | 云南云科生物技术研究院 | miR-6809-5p抑制剂的应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| EP2610342B1 (en) | 2007-09-14 | 2016-05-04 | The Ohio State University Research Foundation | MiRNA Expression in Human Peripheral Blood Microvesicles and uses Thereof |
| KR101235256B1 (ko) | 2010-09-13 | 2013-02-21 | 서울대학교산학협력단 | ｍｉＲＮＡ를 타겟으로 한 신경퇴행성 질환 치료 |
| RU2626540C2 (ru) | 2011-04-18 | 2017-07-28 | Диамир, Ллс | Способы обнаружения патологических изменений в органе или системе органов |
| RU2639509C2 (ru) | 2011-06-27 | 2017-12-21 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | МикроРНК - БИОМАРКЕРЫ, УКАЗЫВАЮЩИЕ НА БОЛЕЗНЬ АЛЬЦГЕЙМЕРА |
| CA2838562A1 (en) | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof |
| WO2013024469A1 (en) | 2011-08-16 | 2013-02-21 | Rosetta Genomics Ltd. | Methods and compositions for diagnosis of alzheimer's desease |
| US20140363469A1 (en) * | 2012-01-19 | 2014-12-11 | Alnylam Pharmaceuticals, Inc. | Viral attenuation and vaccine production |
| EP2733219B1 (en) | 2012-11-16 | 2017-09-20 | Siemens Aktiengesellschaft | Diagnostic miRNA markers for Alzheimer |
| US20140303025A1 (en) | 2013-03-15 | 2014-10-09 | The Translational Genomics Research Institute | Methods for the diagnosis and prognosis of neurodegenerative diseases |
| US9951330B2 (en) | 2013-07-11 | 2018-04-24 | The Trustees Of Columbia University In The City Of New York | Micrornas that silence tau expression |
| JP2015223165A (ja) * | 2014-05-29 | 2015-12-14 | 森永製菓株式会社 | 認知症のバイオマーカー及び認知症の治療薬のスクリーニング方法 |
| KR102511711B1 (ko) * | 2014-06-13 | 2023-03-20 | 국립연구개발법인 고쿠리츠간켄큐센터 | 유방암 검출 키트 또는 디바이스 및 검출 방법 |
| CN118813801A (zh) * | 2014-06-13 | 2024-10-22 | 东丽株式会社 | 大肠癌的检测试剂盒或装置以及检测方法 |
| WO2017059094A2 (en) | 2015-09-29 | 2017-04-06 | Adi Mashiach | System and method for detection of disease in bodily fluids |
| ITUB20155765A1 (it) | 2015-11-20 | 2017-05-20 | Braindtech S R L | Metodi per diagnosi, prognosi e monitoraggio terapeutico di patologie neurologiche, neurodegenerative e infiammatorie basati su microRNA contenuto in microvescicole microglia |
| SG11201806879SA (en) * | 2016-02-24 | 2018-09-27 | Agency Science Tech & Res | A simple one-step real-time molecular system for microrna detection |
| JP2017184642A (ja) | 2016-04-01 | 2017-10-12 | 株式会社ヘルシーパス | 認知症マーカー、それを用いた認知症の評価方法、評価試薬および評価キット |
| WO2017186719A1 (en) | 2016-04-25 | 2017-11-02 | Instytut Biologii Doswiadczalnej Im. Marcelego Nenckiego Polska Akademia Nauk | Microrna biomarkers in blood for diagnosis of alzheimer's disease |
| EP3449009B1 (en) * | 2016-04-25 | 2021-08-18 | Instytut Biologii Doswiadczalnej PAN. im. M. Nenckiego | Microrna biomarkers in blood for diagnosis of alzheimer's disease |
| JP2018023283A (ja) | 2016-07-19 | 2018-02-15 | 鈞 村井 | 刈払機 |
| US10457940B2 (en) * | 2016-09-22 | 2019-10-29 | University Of Massachusetts | AAV treatment of Huntington's disease |
| KR101992539B1 (ko) * | 2016-10-21 | 2019-09-30 | 서울대학교산학협력단 | miRNA 기반의 인지장애 질환 진단용 조성물 및 방법 |
| JP6804947B2 (ja) | 2016-11-24 | 2020-12-23 | 株式会社東芝 | 情報取得装置及び情報取得方法 |
| JP6899091B2 (ja) | 2017-02-24 | 2021-07-07 | 株式会社リコー | シート積載装置、給送装置及び画像形成装置 |
| EP3679157B1 (en) * | 2017-09-05 | 2024-12-18 | Amoneta Diagnostics | Non-coding rnas (ncrna) for the diagnosis of cognitive disorders |
| GB201812334D0 (en) * | 2018-07-27 | 2018-09-12 | Univ Exeter | Compositions and uses thereof |
| EP3891295B1 (en) * | 2018-12-04 | 2026-03-25 | La Trobe University | Methods of diagnosing a disease state |
| WO2021201092A1 (ja) * | 2020-03-31 | 2021-10-07 | 東レ株式会社 | 海馬萎縮を検出するためのキット又はデバイス及び方法 |
-
2019
- 2019-02-12 EP EP24217565.1A patent/EP4498086A3/en not_active Withdrawn
- 2019-02-12 EP EP23216032.5A patent/EP4328587A3/en not_active Withdrawn
- 2019-02-12 EP EP19754972.8A patent/EP3754019B1/en active Active
- 2019-02-12 US US16/969,328 patent/US12529104B2/en active Active
- 2019-02-12 CA CA3091211A patent/CA3091211A1/en active Pending
- 2019-02-12 JP JP2020500479A patent/JP7414237B2/ja active Active
- 2019-02-12 CN CN201980013178.0A patent/CN111742060A/zh active Pending
- 2019-02-12 WO PCT/JP2019/004832 patent/WO2019159884A1/ja not_active Ceased
- 2019-02-12 EP EP25205653.6A patent/EP4697021A2/en active Pending
- 2019-02-12 KR KR1020207022584A patent/KR20200120627A/ko not_active Withdrawn
-
2023
- 2023-12-20 JP JP2023214501A patent/JP2024037978A/ja active Pending
-
2025
- 2025-09-12 JP JP2025152479A patent/JP2025186374A/ja active Pending
- 2025-12-15 US US19/419,995 patent/US20260117305A1/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111218504A (zh) * | 2020-01-17 | 2020-06-02 | 中国辐射防护研究院 | hsa-miR-320d作为辐射暴露诊断的分子标志物的用途 |
| CN115927578A (zh) * | 2022-07-13 | 2023-04-07 | 深圳市拾方杰科技有限公司 | 一种用于自体动静脉内瘘血栓早期预警和诊断的分子标志物及其应用 |
| CN115927578B (zh) * | 2022-07-13 | 2025-12-02 | 深圳市拾方杰科技有限公司 | 一种用于自体动静脉内瘘血栓早期预警和诊断的分子标志物及其应用 |
| CN120204406A (zh) * | 2025-05-28 | 2025-06-27 | 中南大学 | 抑制或检测外泌体miR-3150a-5p表达试剂的应用以及鼻咽癌转移治疗药物和预后制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4697021A2 (en) | 2026-02-18 |
| JP7414237B2 (ja) | 2024-01-16 |
| JP2024037978A (ja) | 2024-03-19 |
| EP4498086A2 (en) | 2025-01-29 |
| EP3754019A4 (en) | 2022-02-16 |
| WO2019159884A1 (ja) | 2019-08-22 |
| US20260117305A1 (en) | 2026-04-30 |
| US12529104B2 (en) | 2026-01-20 |
| US20210047691A1 (en) | 2021-02-18 |
| EP3754019A1 (en) | 2020-12-23 |
| EP4328587A2 (en) | 2024-02-28 |
| EP4328587A3 (en) | 2024-06-05 |
| EP3754019B1 (en) | 2024-01-31 |
| KR20200120627A (ko) | 2020-10-21 |
| EP4498086A3 (en) | 2025-04-02 |
| JPWO2019159884A1 (ja) | 2021-03-11 |
| CN111742060A (zh) | 2020-10-02 |
| JP2025186374A (ja) | 2025-12-23 |
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Legal Events
| Date | Code | Title | Description |
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