KR20170102299A - 비-알콜성 지방간 질환의 치료를 위한 acc 억제제 조합 요법 - Google Patents
비-알콜성 지방간 질환의 치료를 위한 acc 억제제 조합 요법 Download PDFInfo
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- KR20170102299A KR20170102299A KR1020177021086A KR20177021086A KR20170102299A KR 20170102299 A KR20170102299 A KR 20170102299A KR 1020177021086 A KR1020177021086 A KR 1020177021086A KR 20177021086 A KR20177021086 A KR 20177021086A KR 20170102299 A KR20170102299 A KR 20170102299A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201562101726P | 2015-01-09 | 2015-01-09 | |
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| PCT/US2016/012673 WO2016112305A1 (en) | 2015-01-09 | 2016-01-08 | Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease |
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| KR20170102299A true KR20170102299A (ko) | 2017-09-08 |
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| EP (2) | EP3597271A1 (https=) |
| JP (2) | JP2018501276A (https=) |
| KR (1) | KR20170102299A (https=) |
| CN (1) | CN107106873A (https=) |
| AU (1) | AU2016205138A1 (https=) |
| BR (1) | BR112017014341A2 (https=) |
| CA (1) | CA2972919A1 (https=) |
| EA (2) | EA201892625A1 (https=) |
| HK (2) | HK1246232A1 (https=) |
| MX (1) | MX2017008844A (https=) |
| SG (1) | SG11201705361PA (https=) |
| WO (1) | WO2016112305A1 (https=) |
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| WO2021040440A1 (ko) * | 2019-08-30 | 2021-03-04 | (주)셀트리온 | 비알콜성 지방간염(nash, nonalcoholic steatohepatitis) 치료 또는 예방을 위한 약학 조성물 |
| KR20210114887A (ko) * | 2020-03-11 | 2021-09-24 | 동아에스티 주식회사 | 비알콜성지방간염의 예방 또는 치료를 위한 약학적 조성물 |
| KR20230110541A (ko) * | 2020-11-17 | 2023-07-24 | 엥방티바 | 간 질환의 치료를 위한 병용 요법 |
| WO2025225969A1 (ko) * | 2024-04-22 | 2025-10-30 | 연세대학교 원주산학협력단 | CCR2 억제제와 TGF-β 수용체 억제제의 병용투여를 통한 대사이상관련 지방간염 치료 방법 |
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| JP2011525194A (ja) * | 2008-06-20 | 2011-09-15 | キネメッド， インコーポレイテッド | 線維性疾患または病態を治療するための組成物 |
| US20100113473A1 (en) * | 2008-10-30 | 2010-05-06 | Player Mark R | Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor |
| WO2012090219A2 (en) * | 2010-12-31 | 2012-07-05 | Jubilant Biosys Ltd. | Thiazole compounds useful as acetyl-coa carboxylase (acc) inhibitors |
| LT2776038T (lt) * | 2011-11-11 | 2018-04-25 | Gilead Apollo, Llc | Acc inhibitoriai ir jų panaudojimas |
| AU2014262547A1 (en) * | 2013-05-10 | 2015-11-26 | Gilead Apollo, Llc | ACC inhibitors and uses thereof |
| MX2015015422A (es) * | 2013-05-10 | 2016-06-21 | Nimbus Apollo Inc | Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos. |
| CA2911818A1 (en) | 2013-05-10 | 2014-11-13 | Nimbus Apollo, Inc. | Acc inhibitors and uses thereof |
| EA201591959A1 (ru) * | 2013-05-10 | 2016-03-31 | Нимбус Аполло, Инк. | Ингибиторы акк и их применение |
-
2016
- 2016-01-08 JP JP2017535411A patent/JP2018501276A/ja not_active Withdrawn
- 2016-01-08 US US15/541,008 patent/US20180021341A1/en not_active Abandoned
- 2016-01-08 WO PCT/US2016/012673 patent/WO2016112305A1/en not_active Ceased
- 2016-01-08 CN CN201680004801.2A patent/CN107106873A/zh active Pending
- 2016-01-08 EP EP19176040.4A patent/EP3597271A1/en not_active Withdrawn
- 2016-01-08 CA CA2972919A patent/CA2972919A1/en not_active Abandoned
- 2016-01-08 EA EA201892625A patent/EA201892625A1/ru unknown
- 2016-01-08 HK HK18105783.0A patent/HK1246232A1/zh unknown
- 2016-01-08 EA EA201791258A patent/EA201791258A1/ru unknown
- 2016-01-08 AU AU2016205138A patent/AU2016205138A1/en not_active Abandoned
- 2016-01-08 SG SG11201705361PA patent/SG11201705361PA/en unknown
- 2016-01-08 EP EP16735485.1A patent/EP3242722A4/en not_active Withdrawn
- 2016-01-08 BR BR112017014341-0A patent/BR112017014341A2/pt not_active Application Discontinuation
- 2016-01-08 MX MX2017008844A patent/MX2017008844A/es unknown
- 2016-01-08 HK HK18102859.6A patent/HK1243369A1/zh unknown
- 2016-01-08 KR KR1020177021086A patent/KR20170102299A/ko not_active Withdrawn
-
2019
- 2019-05-13 US US16/410,894 patent/US20190381045A1/en not_active Abandoned
-
2020
- 2020-04-15 JP JP2020072689A patent/JP2020109130A/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021040440A1 (ko) * | 2019-08-30 | 2021-03-04 | (주)셀트리온 | 비알콜성 지방간염(nash, nonalcoholic steatohepatitis) 치료 또는 예방을 위한 약학 조성물 |
| KR20210114887A (ko) * | 2020-03-11 | 2021-09-24 | 동아에스티 주식회사 | 비알콜성지방간염의 예방 또는 치료를 위한 약학적 조성물 |
| KR20230110541A (ko) * | 2020-11-17 | 2023-07-24 | 엥방티바 | 간 질환의 치료를 위한 병용 요법 |
| KR20240131458A (ko) * | 2020-11-17 | 2024-08-30 | 엥방티바 | 간 질환의 치료를 위한 병용 요법 |
| WO2025225969A1 (ko) * | 2024-04-22 | 2025-10-30 | 연세대학교 원주산학협력단 | CCR2 억제제와 TGF-β 수용체 억제제의 병용투여를 통한 대사이상관련 지방간염 치료 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018501276A (ja) | 2018-01-18 |
| HK1246232A1 (zh) | 2018-09-07 |
| JP2020109130A (ja) | 2020-07-16 |
| EA201892625A1 (ru) | 2019-07-31 |
| EP3242722A4 (en) | 2018-07-11 |
| MX2017008844A (es) | 2018-03-14 |
| AU2016205138A1 (en) | 2017-07-13 |
| US20180021341A1 (en) | 2018-01-25 |
| EP3242722A1 (en) | 2017-11-15 |
| WO2016112305A1 (en) | 2016-07-14 |
| EA201791258A1 (ru) | 2017-12-29 |
| US20190381045A1 (en) | 2019-12-19 |
| EP3597271A1 (en) | 2020-01-22 |
| HK1243369A1 (zh) | 2018-07-13 |
| CA2972919A1 (en) | 2016-07-14 |
| BR112017014341A2 (pt) | 2018-03-27 |
| CN107106873A (zh) | 2017-08-29 |
| SG11201705361PA (en) | 2017-08-30 |
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