KR20160100407A - 신규한 글루타미나제의 저해제 - Google Patents

신규한 글루타미나제의 저해제 Download PDF

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Publication number
KR20160100407A
KR20160100407A KR1020167021580A KR20167021580A KR20160100407A KR 20160100407 A KR20160100407 A KR 20160100407A KR 1020167021580 A KR1020167021580 A KR 1020167021580A KR 20167021580 A KR20167021580 A KR 20167021580A KR 20160100407 A KR20160100407 A KR 20160100407A
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South Korea
Prior art keywords
substituted
unsubstituted
alkyl
pyridin
acetamide
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Korean (ko)
Inventor
프라샨트 카쉬나쓰 바바르
스와루프 쿠마르 벤카타 사티야 박칼란카
스리칸트 비스완다
메리카푸디 가야트리 스와루프
고빈다라주루 바부
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리젠 파마슈티컬스 소시에떼 아노님
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Publication of KR20160100407A publication Critical patent/KR20160100407A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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