KR20160034901A - 서열 조작에 최적화된 ｃｒｉｓｐｒ-ｃａｓ 이중 닉카아제 시스템, 방법 및 조성물 - Google Patents

서열 조작에 최적화된 ｃｒｉｓｐｒ-ｃａｓ 이중 닉카아제 시스템, 방법 및 조성물 Download PDF

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KR20160034901A
KR20160034901A KR1020167001293A KR20167001293A KR20160034901A KR 20160034901 A KR20160034901 A KR 20160034901A KR 1020167001293 A KR1020167001293 A KR 1020167001293A KR 20167001293 A KR20167001293 A KR 20167001293A KR 20160034901 A KR20160034901 A KR 20160034901A
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sequence
crispr
tracr
sequences
target
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Korean (ko)
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펑 장
패트릭 수
치에-유 린
페이 란
Original Assignee
더 브로드 인스티튜트, 인코퍼레이티드
프레지던트 앤드 펠로우즈 오브 하바드 칼리지
매사추세츠 인스티튜트 오브 테크놀로지
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Priority claimed from PCT/US2013/074667 external-priority patent/WO2014093622A2/en
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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KR1020167001293A 2013-06-17 2014-06-10 서열 조작에 최적화된 ｃｒｉｓｐｒ-ｃａｓ 이중 닉카아제 시스템, 방법 및 조성물 Ceased KR20160034901A (ko)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201361836123P 2013-06-17 2013-06-17
US61/836,123 2013-06-17
US201361847537P 2013-07-17 2013-07-17
US61/847,537 2013-07-17
US201361862355P 2013-08-05 2013-08-05
US61/862,355 2013-08-05
US201361871301P 2013-08-28 2013-08-28
US61/871,301 2013-08-28
US201361915383P 2013-12-12 2013-12-12
PCT/US2013/074667 WO2014093622A2 (en) 2012-12-12 2013-12-12 Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
USPCT/US2013/074667 2013-12-12
US61/915,383 2013-12-12
PCT/US2014/041803 WO2014204725A1 (en) 2013-06-17 2014-06-10 Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation

Publications (1)

Publication Number Publication Date
KR20160034901A true KR20160034901A (ko) 2016-03-30

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KR1020167001293A Ceased KR20160034901A (ko) 2013-06-17 2014-06-10 서열 조작에 최적화된 ｃｒｉｓｐｒ-ｃａｓ 이중 닉카아제 시스템, 방법 및 조성물

Country Status (8)

Country Link
US (3) US10711285B2 (https=)
EP (2) EP4245853A3 (https=)
JP (4) JP6665088B2 (https=)
KR (1) KR20160034901A (https=)
CN (1) CN105492611A (https=)
AU (1) AU2014281027A1 (https=)
CA (1) CA2915837A1 (https=)
WO (1) WO2014204725A1 (https=)

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WO2019088496A3 (ko) * 2017-10-31 2019-06-27 주식회사 에이치유비바이오텍 내인성 폴리펩타이드 생산을 위한 재조합 세포 및 방법
WO2022169235A1 (ko) * 2021-02-04 2022-08-11 연세대학교 산학협력단 교정 효율이 개선된 프라임에디팅용 조성물

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