KR20160031040A - 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 - Google Patents
크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 Download PDFInfo
- Publication number
- KR20160031040A KR20160031040A KR1020167005469A KR20167005469A KR20160031040A KR 20160031040 A KR20160031040 A KR 20160031040A KR 1020167005469 A KR1020167005469 A KR 1020167005469A KR 20167005469 A KR20167005469 A KR 20167005469A KR 20160031040 A KR20160031040 A KR 20160031040A
- Authority
- KR
- South Korea
- Prior art keywords
- renal
- rats
- group
- subject
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85850906P | 2006-11-13 | 2006-11-13 | |
| US60/858,509 | 2006-11-13 | ||
| PCT/US2007/084573 WO2008064015A1 (en) | 2006-11-13 | 2007-11-13 | Methods for preserving renal function using xanthine oxidoreductase inhibitors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20157001953A Division KR20150024919A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160031040A true KR20160031040A (ko) | 2016-03-21 |
Family
ID=39430048
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167005469A Ceased KR20160031040A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
| KR20157001953A Ceased KR20150024919A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
| KR1020097012310A Ceased KR20090103879A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20157001953A Ceased KR20150024919A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
| KR1020097012310A Ceased KR20090103879A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080269226A1 (enExample) |
| EP (1) | EP2101761A4 (enExample) |
| JP (3) | JP2010509372A (enExample) |
| KR (3) | KR20160031040A (enExample) |
| CN (1) | CN101677999A (enExample) |
| AU (1) | AU2007323919A1 (enExample) |
| BR (1) | BRPI0718611A2 (enExample) |
| CA (1) | CA2669935A1 (enExample) |
| MX (1) | MX2009004984A (enExample) |
| RU (1) | RU2508099C2 (enExample) |
| WO (1) | WO2008064015A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008545627A (ja) * | 2005-05-09 | 2008-12-18 | タツプ・フアーマシユーテイカル・プロダクツ・インコーポレイテツド | 腎結石症を治療する方法 |
| US20070167454A1 (en) * | 2005-08-03 | 2007-07-19 | Christopher Lademacher | Methods for treating hypertension |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| MX2009007680A (es) * | 2007-01-19 | 2011-08-03 | Takeda Pharmaceuticals North America Inc | Metodos para prevenir o reducir el numero de expansiones graduales de gota utilizando inhibidores de oxidoreductasa de xantina y agentes anti-inflamatorios. |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| IT1400609B1 (it) | 2010-05-10 | 2013-06-14 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e metformina e loro uso. |
| IT1400309B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e calcio antagonisti e loro uso. |
| IT1400310B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e statine e loro uso. |
| IT1400311B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e antagonisti del recettore dell'angiotensina ii e loro uso. |
| MY167126A (en) * | 2010-06-16 | 2018-08-13 | Takeda Pharmaceuticals Usa Inc | Novel modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors |
| CN102958521A (zh) * | 2010-06-25 | 2013-03-06 | 帝人制药株式会社 | 缓释性高血压和肾功能不全治疗剂 |
| CN102372679A (zh) * | 2010-08-27 | 2012-03-14 | 北京润德康医药技术有限公司 | 一种非布司他水溶性衍生物及其制备方法 |
| CA2812034C (en) | 2010-09-10 | 2018-10-23 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for concomitant treatment of theophylline and febuxostat |
| WO2012060308A1 (ja) * | 2010-11-01 | 2012-05-10 | 株式会社 三和化学研究所 | 腎機能障害の予防又は治療に用いる医薬 |
| CN102757403B (zh) * | 2011-04-27 | 2015-04-29 | 浙江九洲药业股份有限公司 | 一种非布索坦衍生物及其制备方法 |
| TW201328692A (zh) * | 2011-10-11 | 2013-07-16 | Univ Osaka | 脫髓鞘疾病之治療劑及預防劑 |
| TW201334779A (zh) | 2012-01-27 | 2013-09-01 | Teijin Pharma Ltd | 糖尿病的治療藥 |
| CA2889326A1 (en) * | 2012-10-23 | 2014-05-01 | Teijin Pharma Limited | Therapeutic or prophylactic agent for tumor lysis syndrome |
| CN103265636B (zh) * | 2013-05-23 | 2015-09-16 | 中国药科大学 | 一种具有降血糖作用的新型肽 |
| CN104548066A (zh) * | 2015-01-19 | 2015-04-29 | 中国药科大学 | 一种具有降血糖作用的新型肽的新用途 |
| CN105294584A (zh) * | 2015-11-30 | 2016-02-03 | 中国医科大学 | 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途 |
| ES2842577T3 (es) | 2016-02-19 | 2021-07-14 | Nezu Life Science Co Ltd | Fármaco terapéutico o profiláctico para la demencia |
| CN106279024B (zh) * | 2016-07-19 | 2018-09-14 | 华南理工大学 | 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用 |
| KR20230119303A (ko) * | 2022-02-07 | 2023-08-16 | (주)인드림헬스케어 | 높은 혈중 요산 농도를 갖는 대상체의 만성 신장 질환의 예방 또는 치료를 위한 알로푸리놀, 페북소스타트 또는 이들의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3079303A (en) * | 1958-12-11 | 1963-02-26 | Smith Kline French Lab | Basic tablet granulation and process of using same |
| US4058614A (en) * | 1973-12-04 | 1977-11-15 | Merck & Co., Inc. | Substituted imidazole compounds and therapeutic compositions therewith |
| US4296122A (en) * | 1975-07-09 | 1981-10-20 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids |
| DE2727802A1 (de) * | 1977-06-21 | 1979-04-19 | Hoechst Ag | Sulfamoyl-arylketone und verfahren zu ihrer herstellung |
| US4510322A (en) * | 1981-07-13 | 1985-04-09 | Merck & Co., Inc. | Indacrinone having enhanced uricosuric |
| US4632930A (en) * | 1984-11-30 | 1986-12-30 | E. I. Du Pont De Nemours And Company | Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives |
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| DE122008000051I1 (de) * | 1990-11-30 | 2009-02-05 | Teijin Ltd | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
| JPH07121953B2 (ja) * | 1991-11-30 | 1995-12-25 | 株式會社眞露 | 新規なピロリジン誘導体類及びこれらの塩類、その製造方法、薬用組成物及び経皮投与用調合物 |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| US5514681A (en) * | 1994-08-17 | 1996-05-07 | Virginia Tech Intellectual Properties, Inc. | Compositions and methods for controlling pest insects |
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| US6037344A (en) * | 1994-08-17 | 2000-03-14 | Virginia Tech Intellectual Properties, Inc. | Compositions and methods for controlling pest insects |
| AUPM835394A0 (en) * | 1994-09-23 | 1994-10-13 | King, Michael G. Dr. | Method for controlling or eliminating the need to smoke tobacco, and for treating ailments which may lead to the said need |
| KR100308332B1 (ko) * | 1995-04-07 | 2002-09-17 | 데이진 가부시키가이샤 | 기관또는조직보호제 |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
| US5965625A (en) * | 1997-03-21 | 1999-10-12 | King; Michael Glenn | Compositions and methods for the control of smoking |
| WO1999024038A1 (en) * | 1997-11-07 | 1999-05-20 | Johns Hopkins University | Methods for treatment of disorders of cardiac contractility |
| ID25775A (id) * | 1998-06-19 | 2000-11-02 | Teijin Ltd | Polimorf dari asam 2-(3-siano-4-isobutiloksifenil)-4-metil-5-tiazol karboksilat dan metoda pembuatannya |
| US6281222B1 (en) * | 1999-08-19 | 2001-08-28 | Inotek Corporation | Compositions and method for treatment of acetaminophen intoxication |
| US7799794B2 (en) * | 2000-06-28 | 2010-09-21 | Merck Sharp & Dohme Corp. | Treatment for cardiovascular disease |
| ITMI20010206A1 (it) * | 2001-02-02 | 2002-08-02 | Dompe Spa | Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz |
| WO2002085380A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for treating gout and reducing serum uric acid |
| JP2004528332A (ja) * | 2001-04-18 | 2004-09-16 | ジェンザイム コーポレーション | 痛風を治療する方法および尿酸を結合する方法 |
| CA2462132C (en) * | 2002-01-28 | 2010-08-10 | Fuji Yakuhin Co., Ltd. | 1,2,4-triazole compounds |
| US7361676B2 (en) * | 2002-03-28 | 2008-04-22 | Teijin Limited | Solid preparation containing single crystal form |
| US20060040945A1 (en) * | 2002-05-17 | 2006-02-23 | Merckle Gmbh | Annellated pyrrole compounds as proton pump inhibitors for treating ulcer |
| US7078423B2 (en) * | 2002-07-18 | 2006-07-18 | Inotek Pharmaceuticals Corporation | 5-Aryltetrazole compounds, compositions thereof, and uses therefor |
| US20040122067A1 (en) * | 2002-12-20 | 2004-06-24 | Lin Zhao | Treatment of chronic heart failure |
| US20040121004A1 (en) * | 2002-12-20 | 2004-06-24 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| US20040131676A1 (en) * | 2002-12-20 | 2004-07-08 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| WO2005018635A2 (en) * | 2003-08-07 | 2005-03-03 | Cardiome Pharma Corp. | Ion channel modulating activity i |
| WO2006028342A1 (en) * | 2004-09-06 | 2006-03-16 | Biosynergen, Inc. | A novel xanthine oxidase inhibitor and a pharmaceutical composition containing the same |
| AU2005306772A1 (en) * | 2004-11-19 | 2006-05-26 | Shiva Biomedical, Llc | Methods of treating erythropoietin-resistance |
| JP2008545627A (ja) * | 2005-05-09 | 2008-12-18 | タツプ・フアーマシユーテイカル・プロダクツ・インコーポレイテツド | 腎結石症を治療する方法 |
| US20070167454A1 (en) * | 2005-08-03 | 2007-07-19 | Christopher Lademacher | Methods for treating hypertension |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| MX2009007680A (es) * | 2007-01-19 | 2011-08-03 | Takeda Pharmaceuticals North America Inc | Metodos para prevenir o reducir el numero de expansiones graduales de gota utilizando inhibidores de oxidoreductasa de xantina y agentes anti-inflamatorios. |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| CA2812034C (en) * | 2010-09-10 | 2018-10-23 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for concomitant treatment of theophylline and febuxostat |
-
2007
- 2007-11-13 KR KR1020167005469A patent/KR20160031040A/ko not_active Ceased
- 2007-11-13 RU RU2009122505/15A patent/RU2508099C2/ru not_active IP Right Cessation
- 2007-11-13 MX MX2009004984A patent/MX2009004984A/es unknown
- 2007-11-13 AU AU2007323919A patent/AU2007323919A1/en not_active Abandoned
- 2007-11-13 JP JP2009536541A patent/JP2010509372A/ja active Pending
- 2007-11-13 WO PCT/US2007/084573 patent/WO2008064015A1/en not_active Ceased
- 2007-11-13 BR BRPI0718611-8A2A patent/BRPI0718611A2/pt not_active IP Right Cessation
- 2007-11-13 US US11/939,112 patent/US20080269226A1/en not_active Abandoned
- 2007-11-13 EP EP07864338A patent/EP2101761A4/en not_active Withdrawn
- 2007-11-13 CA CA002669935A patent/CA2669935A1/en not_active Abandoned
- 2007-11-13 KR KR20157001953A patent/KR20150024919A/ko not_active Ceased
- 2007-11-13 KR KR1020097012310A patent/KR20090103879A/ko not_active Ceased
- 2007-11-13 CN CN200780049607A patent/CN101677999A/zh active Pending
-
2013
- 2013-09-20 JP JP2013195396A patent/JP2014012726A/ja active Pending
-
2016
- 2016-06-08 JP JP2016114133A patent/JP6233899B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007323919A1 (en) | 2008-05-29 |
| US20080269226A1 (en) | 2008-10-30 |
| MX2009004984A (es) | 2009-09-23 |
| JP2016188231A (ja) | 2016-11-04 |
| JP2014012726A (ja) | 2014-01-23 |
| WO2008064015A1 (en) | 2008-05-29 |
| CN101677999A (zh) | 2010-03-24 |
| BRPI0718611A2 (pt) | 2014-02-25 |
| EP2101761A4 (en) | 2010-01-27 |
| RU2508099C2 (ru) | 2014-02-27 |
| RU2009122505A (ru) | 2010-12-20 |
| KR20150024919A (ko) | 2015-03-09 |
| JP6233899B2 (ja) | 2017-11-22 |
| CA2669935A1 (en) | 2008-05-29 |
| EP2101761A1 (en) | 2009-09-23 |
| JP2010509372A (ja) | 2010-03-25 |
| KR20090103879A (ko) | 2009-10-01 |
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