KR20150003169A - Ｄｌｌ3 조절물질들 및 사용 방법 - Google Patents

Ｄｌｌ3 조절물질들 및 사용 방법 Download PDF

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KR20150003169A
KR20150003169A KR1020147026844A KR20147026844A KR20150003169A KR 20150003169 A KR20150003169 A KR 20150003169A KR 1020147026844 A KR1020147026844 A KR 1020147026844A KR 20147026844 A KR20147026844 A KR 20147026844A KR 20150003169 A KR20150003169 A KR 20150003169A
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Prior art keywords
antibody
dll3
antibodies
cells
seq
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Korean (ko)
Inventor
로버트 에이. 스털
로라 손더스
스콧 제이. 딜라
오리트 푸어드
데이비드 리우
마이클 토고브
후이 샤오
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스템 센트알엑스 인코포레이티드
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Application filed by 스템 센트알엑스 인코포레이티드 filed Critical 스템 센트알엑스 인코포레이티드
Publication of KR20150003169A publication Critical patent/KR20150003169A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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