KR20120102688A - 헥사하이드로인데노파이리딘과 옥타하이드로벤조퀴이노린의 아릴- 그리고 헤테로아릴카르보닐 유도체들 - Google Patents

헥사하이드로인데노파이리딘과 옥타하이드로벤조퀴이노린의 아릴- 그리고 헤테로아릴카르보닐 유도체들 Download PDF

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KR20120102688A
KR20120102688A KR1020127014706A KR20127014706A KR20120102688A KR 20120102688 A KR20120102688 A KR 20120102688A KR 1020127014706 A KR1020127014706 A KR 1020127014706A KR 20127014706 A KR20127014706 A KR 20127014706A KR 20120102688 A KR20120102688 A KR 20120102688A
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alkyl
oxo
group
carbonyl
dihydro
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Korean (ko)
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마티아스 에크하르트
스테판 피터스
헤르베르트 날
프랑크 힘멜바흐
링항 좡
Original Assignee
베링거 인겔하임 인터내셔날 게엠베하
비타이 파마슈티컬즈, 인코포레이티드
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Application filed by 베링거 인겔하임 인터내셔날 게엠베하, 비타이 파마슈티컬즈, 인코포레이티드 filed Critical 베링거 인겔하임 인터내셔날 게엠베하
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D498/04—Ortho-condensed systems
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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020127014706A 2009-11-06 2010-11-05 헥사하이드로인데노파이리딘과 옥타하이드로벤조퀴이노린의 아릴- 그리고 헤테로아릴카르보닐 유도체들 Ceased KR20120102688A (ko)

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Application Number Priority Date Filing Date Title
EP09175233 2009-11-06
EP09175233.7 2009-11-06

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KR20120102688A true KR20120102688A (ko) 2012-09-18

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KR1020127014706A Ceased KR20120102688A (ko) 2009-11-06 2010-11-05 헥사하이드로인데노파이리딘과 옥타하이드로벤조퀴이노린의 아릴- 그리고 헤테로아릴카르보닐 유도체들

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US (3) US8497281B2 (https=)
EP (1) EP2496559B1 (https=)
JP (1) JP5796015B2 (https=)
KR (1) KR20120102688A (https=)
CN (2) CN102666491B (https=)
AP (1) AP2012006248A0 (https=)
AR (1) AR078887A1 (https=)
AU (1) AU2010315077B2 (https=)
BR (1) BR112012010792A2 (https=)
CA (1) CA2778161A1 (https=)
CL (1) CL2012001043A1 (https=)
CO (1) CO6531441A2 (https=)
EA (1) EA022323B1 (https=)
GE (1) GEP20156330B (https=)
IL (1) IL218652A0 (https=)
IN (1) IN2012DN02807A (https=)
MA (1) MA33776B1 (https=)
MX (1) MX2012005309A (https=)
MY (1) MY159922A (https=)
NZ (1) NZ598950A (https=)
PE (1) PE20121182A1 (https=)
PH (1) PH12012500904A1 (https=)
SG (1) SG179569A1 (https=)
TW (1) TWI531571B (https=)
UA (1) UA109643C2 (https=)
UY (1) UY33001A (https=)
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