KR20080014934A - 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체 - Google Patents

단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체 Download PDF

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KR20080014934A
KR20080014934A KR1020087002849A KR20087002849A KR20080014934A KR 20080014934 A KR20080014934 A KR 20080014934A KR 1020087002849 A KR1020087002849 A KR 1020087002849A KR 20087002849 A KR20087002849 A KR 20087002849A KR 20080014934 A KR20080014934 A KR 20080014934A
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formula
alkyl
compound
mmol
residue
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라이너 알베르트
니겔 그라함 쿠크
실바인 코텐스
클라우스 에르하르트
장-삐에르 에베노우
리차드 세드라니
마트 페터 본
유르겐 바그너
게르하르트 젠크
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노파르티스 아게
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  • Pain & Pain Management (AREA)
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KR1020087002849A 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체 Ceased KR20080014934A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24640000P 2000-11-07 2000-11-07
US60/246,400 2000-11-07
US28370501P 2001-04-13 2001-04-13
US60/283,705 2001-04-13

Related Parent Applications (1)

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KR1020067017472A Division KR100916613B1 (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체

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KR20080014934A true KR20080014934A (ko) 2008-02-14

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KR1020067017472A Expired - Fee Related KR100916613B1 (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체
KR1020037005805A Expired - Fee Related KR100748386B1 (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체
KR1020087002849A Ceased KR20080014934A (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체

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KR1020067017472A Expired - Fee Related KR100916613B1 (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체
KR1020037005805A Expired - Fee Related KR100748386B1 (ko) 2000-11-07 2001-11-05 단백질 키나제 c 억제제로서의 인돌릴말레이미드 유도체

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EP (2) EP2070921A1 (enExample)
JP (1) JP4234426B2 (enExample)
KR (3) KR100916613B1 (enExample)
CN (1) CN1253449C (enExample)
AR (1) AR035211A1 (enExample)
AT (1) ATE445613T1 (enExample)
AU (3) AU2181002A (enExample)
BR (1) BRPI0115193B1 (enExample)
CA (1) CA2428133C (enExample)
CY (1) CY1110564T1 (enExample)
CZ (1) CZ307144B6 (enExample)
DE (1) DE60140201D1 (enExample)
DK (1) DK1337527T3 (enExample)
EC (1) ECSP104578A (enExample)
ES (1) ES2332770T3 (enExample)
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MY (2) MY127157A (enExample)
NO (1) NO327427B1 (enExample)
NZ (2) NZ525656A (enExample)
PE (1) PE20020544A1 (enExample)
PL (1) PL208794B1 (enExample)
PT (1) PT1337527E (enExample)
RU (2) RU2329263C2 (enExample)
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SI (1) SI1337527T1 (enExample)
SK (1) SK287919B6 (enExample)
TW (2) TWI290553B (enExample)
WO (1) WO2002038561A1 (enExample)

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RU2004135382A (ru) 2002-06-05 2005-06-27 Янссен Фармацевтика Н.В. (Be) Замещенные пирролины в качестве ингибиторов киназы
GB0303319D0 (en) 2003-02-13 2003-03-19 Novartis Ag Organic compounds
WO2005025602A1 (en) 2003-09-16 2005-03-24 Garvan Institute Of Medical Research METHODS FOR IDENTIFYING MODULATORS OF PROTEIN KINASE C-EPSILON (PKCϵ) AND METHOD OF TREATMENT OF ABERRANT GLUCOSE METABOLISM ASSOCIATED THEREWITH
EP1682103A1 (en) * 2003-10-27 2006-07-26 Novartis AG Indolyl-pyrroledione derivatives for the treatment of neurological and vascular disorders related to beta-amyloid generation and/or aggregation
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
GB0401089D0 (en) * 2004-01-19 2004-02-18 Novartis Ag Organic compounds
EP1709030B1 (en) * 2004-01-19 2008-04-02 Novartis AG Indolylmaleimide derivatives
US20070232658A1 (en) * 2004-04-08 2007-10-04 Jurgen Wagner Protein Kinase C Inhibitors for the Treatment of Autoimmune Diseases and of Transplant Rejiction
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CA2589127C (en) 2004-12-08 2013-02-05 Johannes Gutenberg-Universitat Mainz 3-(indolyl)-4-arylmaleimide derivatives and their use as angiogenesis inhibitors
GB0504203D0 (en) * 2005-03-01 2005-04-06 Novartis Ag Organic compounds
GB0507918D0 (en) 2005-04-19 2005-05-25 Novartis Ag Organic compounds
WO2006117212A2 (en) 2005-05-04 2006-11-09 Develogen Aktiengesellschaft Use of gsk-3 inhibitors for preventing and treating pancreatic autoimmune disorders
GB0511060D0 (en) 2005-05-31 2005-07-06 Novartis Ag Organic compounds
US7781438B2 (en) 2005-07-11 2010-08-24 Novartis Ag Indolylmaleimide derivatives
PL2848258T3 (pl) 2005-10-26 2018-06-29 Novartis Ag Leczenie rodzinnej gorączki śródziemnomorskiej przeciwciałami przeciwko IL-1beta
AU2006314444C1 (en) 2005-11-21 2018-01-04 Novartis Ag Neuroendocrine tumor treatment using mTOR inhibitors
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GB0613162D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic compounds
US20100179175A1 (en) * 2006-08-23 2010-07-15 Sivak Jeremy M Use of pkc inhibitors in ocular diseases
PE20081133A1 (es) * 2006-10-20 2008-09-16 Novartis Ag Cristal acetato de 3-(1h-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona
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ES2410955T3 (es) 2006-12-19 2013-07-04 Novartis Ag Derivados de indolilmaleimida como inhibidores de la quinasa
JP2010520879A (ja) * 2007-03-09 2010-06-17 ノバルティス アーゲー 3−(1h−インドール−3−イル)−4−[2−(4−メチル−ピペラジン−1−イル)−キナゾリン−4−イル]−ピロール−2,5−ジオンの塩
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