GB201111427D0 - Novel bisindolylmaleimides, pan-pkc inhibitors - Google Patents
Novel bisindolylmaleimides, pan-pkc inhibitorsInfo
- Publication number
- GB201111427D0 GB201111427D0 GB201111427A GB201111427A GB201111427D0 GB 201111427 D0 GB201111427 D0 GB 201111427D0 GB 201111427 A GB201111427 A GB 201111427A GB 201111427 A GB201111427 A GB 201111427A GB 201111427 D0 GB201111427 D0 GB 201111427D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- inhibitors
- bisindolylmaleimides
- pan
- novel
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Abstract
The present invention relates to new kinase inhibitors, more specifically soft PKC inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new soft PKC inhibitors compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including autoimmune and inflammatory diseases.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201111427A GB201111427D0 (en) | 2011-07-05 | 2011-07-05 | Novel bisindolylmaleimides, pan-pkc inhibitors |
PCT/EP2012/062951 WO2013004709A1 (en) | 2011-07-05 | 2012-07-04 | Indolylmaleimides as soft pan-pkc inhibitors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201111427A GB201111427D0 (en) | 2011-07-05 | 2011-07-05 | Novel bisindolylmaleimides, pan-pkc inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201111427D0 true GB201111427D0 (en) | 2011-08-17 |
Family
ID=44512094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB201111427A Ceased GB201111427D0 (en) | 2011-07-05 | 2011-07-05 | Novel bisindolylmaleimides, pan-pkc inhibitors |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB201111427D0 (en) |
WO (1) | WO2013004709A1 (en) |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL89167A (en) * | 1988-02-10 | 1994-02-27 | Hoffmann La Roche | Substituted pyrroles, their manufacture and pharmaceutical compositions containing them |
US5380746A (en) * | 1989-05-05 | 1995-01-10 | Goedecke Aktiengesellschaft | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
PE91698A1 (en) * | 1996-07-29 | 1998-12-24 | Hoffmann La Roche | SUBSTITUTED PYRROLES |
PE91598A1 (en) * | 1996-07-29 | 1998-12-24 | Hoffmann La Roche | SUBSTITUTED PYRROLES |
GB9828640D0 (en) * | 1998-12-23 | 1999-02-17 | Smithkline Beecham Plc | Novel method and compounds |
WO2001044247A2 (en) * | 1999-12-16 | 2001-06-21 | Eli Lilly And Company | Agents and methods for the treatment of proliferative diseases |
SG159378A1 (en) * | 2000-11-07 | 2010-03-30 | Novartis Ag | Indolylmaleimide derivatives as protein kinase c inhibitors |
EP1645286A1 (en) * | 2003-04-18 | 2006-04-12 | Kyowa Hakko Kogyo Co., Ltd. | Drug for nerve regeneration |
BRPI0613064A2 (en) * | 2005-07-11 | 2010-12-21 | Novartis Ag | indolylmaleimide derivatives as protein kinase inhibitors |
ES2410955T3 (en) * | 2006-12-19 | 2013-07-04 | Novartis Ag | Indolylmaleimide derivatives as kinase inhibitors |
EP2125683B1 (en) * | 2006-12-19 | 2013-10-23 | The Board of Trustees of the University of Illinois | 3-benzofuranyl-4-indolyl-maleimides as potent gsk-3 inhibitors for neurodegenerative disorders |
-
2011
- 2011-07-05 GB GB201111427A patent/GB201111427D0/en not_active Ceased
-
2012
- 2012-07-04 WO PCT/EP2012/062951 patent/WO2013004709A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2013004709A1 (en) | 2013-01-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |