KR102751864B1 - 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 - Google Patents
미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 Download PDFInfo
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- KR102751864B1 KR102751864B1 KR1020227025177A KR20227025177A KR102751864B1 KR 102751864 B1 KR102751864 B1 KR 102751864B1 KR 1020227025177 A KR1020227025177 A KR 1020227025177A KR 20227025177 A KR20227025177 A KR 20227025177A KR 102751864 B1 KR102751864 B1 KR 102751864B1
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- myostatin
- amino acid
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- adnectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
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- G—PHYSICS
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
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- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
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- Pain & Pain Management (AREA)
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- Marine Sciences & Fisheries (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261700697P | 2012-09-13 | 2012-09-13 | |
| US61/700,697 | 2012-09-13 | ||
| US201361780005P | 2013-03-13 | 2013-03-13 | |
| US61/780,005 | 2013-03-13 | ||
| KR1020207034555A KR102424590B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
| PCT/US2013/059458 WO2014043344A1 (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207034555A Division KR102424590B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20220107082A KR20220107082A (ko) | 2022-08-01 |
| KR102751864B1 true KR102751864B1 (ko) | 2025-01-07 |
Family
ID=49253416
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227025177A Active KR102751864B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
| KR1020207034555A Active KR102424590B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
| KR1020157009067A Active KR102187714B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207034555A Active KR102424590B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
| KR1020157009067A Active KR102187714B1 (ko) | 2012-09-13 | 2013-09-12 | 미오스타틴에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질 |
Country Status (33)
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3056568B1 (en) | 2006-03-31 | 2021-09-15 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| CN101874042B9 (zh) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| CA2721052C (en) | 2008-04-11 | 2023-02-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| EP2576615B1 (en) | 2010-05-26 | 2016-03-30 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins having improved stability |
| CN103328632A (zh) | 2010-11-30 | 2013-09-25 | 中外制药株式会社 | 与多分子的抗原重复结合的抗原结合分子 |
| US9469676B2 (en) * | 2011-04-13 | 2016-10-18 | Bristol-Myers Squibb Company | Fc fusion proteins comprising novel linkers or arrangements |
| WO2014030750A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
| WO2014030728A1 (ja) | 2012-08-24 | 2014-02-27 | 中外製薬株式会社 | FcγRIIb特異的Fc領域改変体 |
| PL3564258T3 (pl) | 2012-09-13 | 2021-10-25 | Bristol-Myers Squibb Company | Oparte na fibronektynie białka z domeną rusztowania, które wiążą się z miostatyną |
| ES2715710T3 (es) | 2013-01-25 | 2019-06-05 | Shire Human Genetic Therapies | Folistatina en el tratamiento de la distrofía muscular de Duchenne |
| US20150361159A1 (en) | 2013-02-01 | 2015-12-17 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins |
| EP2953968B1 (en) | 2013-02-06 | 2018-07-25 | Bristol-Myers Squibb Company | Fibronectin type iii domain proteins with enhanced solubility |
| US10065987B2 (en) | 2013-02-12 | 2018-09-04 | Bristol-Myers Squibb Company | High pH protein refolding methods |
| CN113621057A (zh) | 2013-04-02 | 2021-11-09 | 中外制药株式会社 | Fc区变体 |
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