SI3564258T1 - Ogrodni domenski proteini na osnovi fibronektina, ki se vežejo na miostatin - Google Patents
Ogrodni domenski proteini na osnovi fibronektina, ki se vežejo na miostatinInfo
- Publication number
- SI3564258T1 SI3564258T1 SI201331889T SI201331889T SI3564258T1 SI 3564258 T1 SI3564258 T1 SI 3564258T1 SI 201331889 T SI201331889 T SI 201331889T SI 201331889 T SI201331889 T SI 201331889T SI 3564258 T1 SI3564258 T1 SI 3564258T1
- Authority
- SI
- Slovenia
- Prior art keywords
- myostatin
- bind
- domain proteins
- based scaffold
- scaffold domain
- Prior art date
Links
- 102100037362 Fibronectin Human genes 0.000 title 1
- 108010067306 Fibronectins Proteins 0.000 title 1
- 102100039939 Growth/differentiation factor 8 Human genes 0.000 title 1
- 108010056852 Myostatin Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261700697P | 2012-09-13 | 2012-09-13 | |
US201361780005P | 2013-03-13 | 2013-03-13 | |
EP19162848.6A EP3564258B1 (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3564258T1 true SI3564258T1 (sl) | 2021-07-30 |
Family
ID=49253416
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201331889T SI3564258T1 (sl) | 2012-09-13 | 2013-09-12 | Ogrodni domenski proteini na osnovi fibronektina, ki se vežejo na miostatin |
SI201331453T SI2895503T1 (sl) | 2012-09-13 | 2013-09-12 | Ogrodni proteini domena na osnovi fibronektina, ki se vežejo na miostatin |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201331453T SI2895503T1 (sl) | 2012-09-13 | 2013-09-12 | Ogrodni proteini domena na osnovi fibronektina, ki se vežejo na miostatin |
Country Status (33)
Country | Link |
---|---|
US (8) | US8933199B2 (sl) |
EP (3) | EP3564258B1 (sl) |
JP (2) | JP6346895B2 (sl) |
KR (3) | KR20220107082A (sl) |
CN (2) | CN104768969B (sl) |
AU (2) | AU2013315482B2 (sl) |
BR (1) | BR112015005466B1 (sl) |
CA (1) | CA2884730C (sl) |
CL (1) | CL2015000500A1 (sl) |
DK (3) | DK3835310T3 (sl) |
EA (1) | EA033536B1 (sl) |
ES (2) | ES2879387T3 (sl) |
FI (1) | FI3835310T3 (sl) |
HK (1) | HK1212717A1 (sl) |
HR (2) | HRP20190845T1 (sl) |
HU (2) | HUE054699T2 (sl) |
IL (3) | IL270110B (sl) |
LT (3) | LT2895503T (sl) |
MX (2) | MX366666B (sl) |
MY (2) | MY172863A (sl) |
NZ (1) | NZ628446A (sl) |
PE (1) | PE20150954A1 (sl) |
PH (1) | PH12015500397B1 (sl) |
PL (3) | PL3835310T3 (sl) |
PT (3) | PT3835310T (sl) |
RS (2) | RS62009B1 (sl) |
SG (3) | SG11201501741YA (sl) |
SI (2) | SI3564258T1 (sl) |
TN (1) | TN2015000086A1 (sl) |
TW (2) | TWI694085B (sl) |
UY (1) | UY35027A (sl) |
WO (1) | WO2014043344A1 (sl) |
ZA (1) | ZA201501457B (sl) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4342995A3 (en) | 2006-03-31 | 2024-05-15 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
WO2009041643A1 (ja) | 2007-09-26 | 2009-04-02 | Chugai Seiyaku Kabushiki Kaisha | Cdrのアミノ酸置換により抗体の等電点を改変する方法 |
JP4954326B2 (ja) | 2008-04-11 | 2012-06-13 | 中外製薬株式会社 | 複数分子の抗原に繰り返し結合する抗原結合分子 |
US9562089B2 (en) * | 2010-05-26 | 2017-02-07 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins having improved stability |
EP4231014A3 (en) | 2010-11-30 | 2024-03-20 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
ES2608835T3 (es) | 2011-04-13 | 2017-04-17 | Bristol-Myers Squibb Company | Proteínas de fusión Fc que comprenden nuevos enlazadores o disposiciones |
US11236168B2 (en) | 2012-08-24 | 2022-02-01 | Chugai Seiyaku Kabushiki Kaisha | Mouse FcγammaRII-specific Fc antibody |
NZ705370A (en) | 2012-08-24 | 2018-06-29 | Chugai Pharmaceutical Co Ltd | Fcγriib-specific fc region variant |
MY172863A (en) * | 2012-09-13 | 2019-12-13 | Bristol Myers Squibb Co | Fibronectin based scaffold domain proteins that bind to myostatin |
EP2948161B1 (en) | 2013-01-25 | 2018-12-12 | Shire Human Genetic Therapies, Inc. | Follistatin in treating duchenne muscular dystrophy |
WO2014120891A2 (en) | 2013-02-01 | 2014-08-07 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins |
US10787498B2 (en) | 2013-02-06 | 2020-09-29 | Bristol-Myers Squibb Company | Fibronectin type III domain proteins with enhanced solubility |
US10065987B2 (en) | 2013-02-12 | 2018-09-04 | Bristol-Myers Squibb Company | High pH protein refolding methods |
KR102318483B1 (ko) | 2013-04-02 | 2021-10-27 | 추가이 세이야쿠 가부시키가이샤 | Fc영역 개변체 |
AU2014262843B2 (en) | 2013-05-06 | 2017-06-22 | Scholar Rock, Inc. | Compositions and methods for growth factor modulation |
CN113150117A (zh) | 2014-03-20 | 2021-07-23 | 百时美施贵宝公司 | 新的结合血清白蛋白的纤连蛋白iii型结构域 |
EP3647322B1 (en) | 2014-03-20 | 2021-10-20 | Bristol-Myers Squibb Company | Stabilized fibronectin based scaffold molecules |
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