KR102189409B1 - 암배아성 항원-관련 세포 부착 분자 (ｃｅａｃａｍ)에 대한 항체 - Google Patents

암배아성 항원-관련 세포 부착 분자 (ｃｅａｃａｍ)에 대한 항체 Download PDF

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KR102189409B1
KR102189409B1 KR1020147010511A KR20147010511A KR102189409B1 KR 102189409 B1 KR102189409 B1 KR 102189409B1 KR 1020147010511 A KR1020147010511 A KR 1020147010511A KR 20147010511 A KR20147010511 A KR 20147010511A KR 102189409 B1 KR102189409 B1 KR 102189409B1
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delete delete
antibody
set forth
cancer
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KR20140069206A (ko
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갈 마르켈
테힐라 벤 모세
야이르 사피어
일라나 만델
제이콥 샤흐터
로나 오르텐베르크
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텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드．
씨씨에이엠 바이오세라퓨틱스 리미티드.
라모트 앳 텔-아비브 유니버시티 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39566—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against immunoglobulins, e.g. anti-idiotypic antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
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  • Biotechnology (AREA)
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  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
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  • Mycology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
KR1020147010511A 2011-10-11 2012-10-10 암배아성 항원-관련 세포 부착 분자 (ｃｅａｃａｍ)에 대한 항체 Active KR102189409B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IL2011/000808 WO2013054320A1 (en) 2011-10-11 2011-10-11 Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
ILPCT/IL2011/000808 2011-10-11
PCT/IL2012/050402 WO2013054331A1 (en) 2011-10-11 2012-10-10 Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)

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KR20140069206A KR20140069206A (ko) 2014-06-09
KR102189409B1 true KR102189409B1 (ko) 2020-12-14

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US (3) US9771431B2 (enExample)
EP (2) EP2744829B1 (enExample)
JP (1) JP6170926B2 (enExample)
KR (1) KR102189409B1 (enExample)
CN (1) CN103987729B (enExample)
AU (1) AU2012322272C1 (enExample)
BR (1) BR112014008893B1 (enExample)
CA (1) CA2851762C (enExample)
ES (2) ES2942314T3 (enExample)
IL (1) IL231931B (enExample)
IN (1) IN2014MN00873A (enExample)
LT (1) LT2744829T (enExample)
PL (2) PL3360899T3 (enExample)
RU (1) RU2650869C2 (enExample)
WO (2) WO2013054320A1 (enExample)

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US9771431B2 (en) 2017-09-26
ES2661488T3 (es) 2018-04-02
WO2013054331A8 (en) 2014-04-10
BR112014008893A2 (pt) 2017-11-28
JP2015502138A (ja) 2015-01-22
CN103987729A (zh) 2014-08-13
EP2744829B1 (en) 2017-12-13
EP2744829A1 (en) 2014-06-25
KR20140069206A (ko) 2014-06-09
WO2013054320A1 (en) 2013-04-18
HK1199646A1 (en) 2015-07-10
AU2012322272B2 (en) 2017-08-17
CA2851762A1 (en) 2013-04-18
IL231931A0 (en) 2014-05-28
CN103987729B (zh) 2017-05-31
US20170355781A1 (en) 2017-12-14
US11891453B2 (en) 2024-02-06
LT2744829T (lt) 2018-03-26
RU2650869C2 (ru) 2018-04-17
WO2013054331A1 (en) 2013-04-18
EP3360899A1 (en) 2018-08-15
US20210070884A1 (en) 2021-03-11
PL2744829T3 (pl) 2018-06-29
IL231931B (en) 2019-06-30
BR112014008893B1 (pt) 2022-04-26
IN2014MN00873A (enExample) 2015-07-03
EP3360899B1 (en) 2023-01-25

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