KR101829488B1 - 인간 다분화능 세포 배양을 위한 단순화된 기본 배지 - Google Patents
인간 다분화능 세포 배양을 위한 단순화된 기본 배지 Download PDFInfo
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- KR101829488B1 KR101829488B1 KR1020137005512A KR20137005512A KR101829488B1 KR 101829488 B1 KR101829488 B1 KR 101829488B1 KR 1020137005512 A KR1020137005512 A KR 1020137005512A KR 20137005512 A KR20137005512 A KR 20137005512A KR 101829488 B1 KR101829488 B1 KR 101829488B1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Gynecology & Obstetrics (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37112810P | 2010-08-05 | 2010-08-05 | |
| US61/371,128 | 2010-08-05 | ||
| PCT/US2011/046796 WO2012019122A2 (en) | 2010-08-05 | 2011-08-05 | Simplified basic media for human pluripotent cell culture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20130099927A KR20130099927A (ko) | 2013-09-06 |
| KR101829488B1 true KR101829488B1 (ko) | 2018-02-14 |
Family
ID=44543813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137005512A Active KR101829488B1 (ko) | 2010-08-05 | 2011-08-05 | 인간 다분화능 세포 배양을 위한 단순화된 기본 배지 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9279103B2 (https=) |
| EP (1) | EP2601288B1 (https=) |
| JP (2) | JP6043999B2 (https=) |
| KR (1) | KR101829488B1 (https=) |
| CN (2) | CN108531444A (https=) |
| AU (1) | AU2011285531B2 (https=) |
| BR (2) | BR112013002811A8 (https=) |
| CA (1) | CA2807418C (https=) |
| DK (1) | DK2601288T3 (https=) |
| IL (1) | IL224431A (https=) |
| SG (1) | SG187699A1 (https=) |
| WO (1) | WO2012019122A2 (https=) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| DK2185693T3 (da) | 2007-07-31 | 2019-09-23 | Lifescan Inc | Differentiering af humane embryoniske stamceller |
| CA2954431C (en) | 2007-11-27 | 2021-08-24 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic cells |
| JP5733986B2 (ja) | 2008-02-21 | 2015-06-10 | ヤンセン バイオテツク,インコーポレーテツド | 細胞の付着、培養、及び剥離のための方法、表面改質されたプレート、並びに組成物 |
| EP2942392B1 (en) | 2008-06-30 | 2018-10-03 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
| US9234178B2 (en) | 2008-10-31 | 2016-01-12 | Janssen Biotech, Inc. | Differentiation of human pluripotent stem cells |
| EP2350265B1 (en) | 2008-10-31 | 2019-04-17 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to the pancreatic endocrine lineage |
| KR101687344B1 (ko) | 2008-11-20 | 2016-12-16 | 얀센 바이오테크 인코포레이티드 | 평면 기재상의 세포 부착 및 배양을 위한 방법 및 조성물 |
| KR101774546B1 (ko) | 2008-11-20 | 2017-09-04 | 얀센 바이오테크 인코포레이티드 | 마이크로-캐리어 상의 만능 줄기 세포 배양 |
| CN102482643B (zh) | 2009-07-20 | 2016-06-29 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| SG10201408552YA (en) | 2009-12-23 | 2015-02-27 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
| PH12012501686A1 (en) | 2010-03-01 | 2020-10-19 | Janssen Biotech Inc | Methods for purifying cells derived from pluripotent stem cells |
| RU2587634C2 (ru) | 2010-05-12 | 2016-06-20 | Янссен Байотек, Инк. | Дифференцирование эмбриональных стволовых клеток человека |
| US9279107B2 (en) | 2010-08-05 | 2016-03-08 | Wisconsin Alumni Research Foundation | Simplified basic media for human pluripotent cell culture |
| PL2853589T3 (pl) | 2010-08-31 | 2018-05-30 | Janssen Biotech, Inc | Różnicowanie ludzkich zarodkowych komórek macierzystych |
| CN103154237B (zh) | 2010-08-31 | 2016-03-16 | 詹森生物科技公司 | 多能干细胞的分化 |
| EP3372672A1 (en) | 2010-08-31 | 2018-09-12 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| AU2012347919B2 (en) | 2011-12-05 | 2017-02-02 | Factor Bioscience Inc. | Methods and products for transfecting cells |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| WO2013090919A1 (en) | 2011-12-16 | 2013-06-20 | Wisconsin Alumni Research Foundation | Fgf-2 having enhanced stability |
| FI2794857T3 (fi) | 2011-12-22 | 2026-03-25 | Janssen Biotech Inc | Ihmisen alkion kantasolujen erilaistaminen yksittäisiksi hormonaalisiksi insuliinipositiivisiksi soluiksi |
| CA2866590A1 (en) | 2012-03-07 | 2013-09-12 | Janssen Biotech, Inc. | Defined media for expansion and maintenance of pluripotent stem cells |
| EP3450544A1 (en) | 2012-06-08 | 2019-03-06 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endodrine cells |
| KR102121086B1 (ko) | 2012-11-01 | 2020-06-09 | 팩터 바이오사이언스 인크. | 세포에서 단백질을 발현시키는 방법들과 생성물들 |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| DK2938723T3 (da) | 2012-12-31 | 2023-02-20 | Janssen Biotech Inc | Differentiering af humane embryonale stamceller til pancreatiske endokrine celler under anvendelse af hb9-regulatorer |
| ES2837763T3 (es) | 2012-12-31 | 2021-07-01 | Janssen Biotech Inc | Cultivo de células madre embrionarias humanas en la interconexión aire-líquido para la diferenciación en células endocrinas pancreáticas |
| BR112015015714A2 (pt) | 2012-12-31 | 2017-07-11 | Janssen Biotech Inc | suspensão e aglomeração de células pluripotentes humanas para diferenciação em célu-las endócrinas pancreáticas |
| SG11201505965TA (en) | 2013-01-31 | 2015-09-29 | Ajinomoto Kk | Culture method for stable undifferentiated proliferation of pluripotent stem cells |
| EP3015551B1 (en) * | 2013-06-28 | 2019-03-06 | Kaneka Corporation | Method for screening for pluripotent stem cell growth-promoting factor |
| WO2015006762A1 (en) * | 2013-07-12 | 2015-01-15 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions for expanding long-term hematopoietic stem cell populations |
| KR101655383B1 (ko) | 2013-07-27 | 2016-09-08 | 고려대학교 산학협력단 | 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물 |
| WO2015042356A1 (en) | 2013-09-19 | 2015-03-26 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Chemically defined culture medium for stem cell maintenance and differentiation |
| EP3099801B1 (en) | 2014-01-31 | 2020-03-18 | Factor Bioscience Inc. | Synthetic rna for use in the treatment of dystrophic epidermolysis bullosa |
| JP6422221B2 (ja) * | 2014-03-04 | 2018-11-14 | 旭化成株式会社 | 多能性幹細胞からなる細胞塊製造方法 |
| US11015169B2 (en) | 2014-03-26 | 2021-05-25 | Kyoto University | Culture medium for pluripotent stem cells |
| WO2015175307A1 (en) | 2014-05-16 | 2015-11-19 | Janssen Biotech, Inc. | Use of small molecules to enhance mafa expression in pancreatic endocrine cells |
| WO2016022992A1 (en) * | 2014-08-07 | 2016-02-11 | Duke University | Compositions and methods for the reprogramming of cells into cardiomyocytes |
| AU2015305515B2 (en) | 2014-08-19 | 2020-12-03 | FUJIFILM Cellular Dynamics, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
| WO2016123100A1 (en) | 2015-01-26 | 2016-08-04 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| SG11201803145RA (en) | 2015-11-04 | 2018-05-30 | Fate Therapeutics Inc | Methods and compositions for inducing hematopoietic cell differentiation |
| KR20250141836A (ko) | 2015-11-04 | 2025-09-29 | 페이트 세러퓨틱스, 인코포레이티드 | 만능 세포의 유전자 조작 |
| US10420803B2 (en) | 2016-04-14 | 2019-09-24 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells to intestinal midgut endoderm cells |
| IL308824A (en) | 2016-08-17 | 2024-01-01 | Factor Bioscience Inc | Nucleic acid products and methods of administration thereof |
| KR101953573B1 (ko) * | 2017-03-31 | 2019-03-05 | 한양대학교 에리카산학협력단 | 난황줄기세포 배양을 위한 우태아혈청 조성물 및 이의 제조방법 |
| SG11201909331UA (en) * | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
| TWI814738B (zh) | 2017-09-08 | 2023-09-11 | 日商日產化學股份有限公司 | 細胞保存材料 |
| KR102121602B1 (ko) * | 2018-06-27 | 2020-06-10 | 주식회사 티아라줄기세포연구소 | 지방줄기세포배양용 배지 조성물 제조방법, 지방줄기세포배양용 배지 조성물 제조방법과 줄기세포 유효성분 3저 추출법을 이용한 줄기세포파쇄추출물(쉘드줄기세포) 제조방법, 이를 이용한 항관절염 치료용 조성물, 이를 이용한 염증억제 효과를 갖는 조성물 및 세포재생 효과를 갖는 조성물 |
| JP7474520B2 (ja) * | 2019-04-05 | 2024-04-25 | ザ・ユニバーシティ・オブ・ホンコン | 哺乳類の拡大ポテンシャル幹細胞のための培地、その組成物および方法 |
| CA3145425A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| JP2022548776A (ja) * | 2019-09-19 | 2022-11-21 | ノースウェスタン ユニバーシティ | ヒト人工多能性幹細胞のための費用効果の高い培地およびプロトコル |
| CN110564673A (zh) * | 2019-09-26 | 2019-12-13 | 广东工业大学 | 一种干细胞培养液及其应用 |
| CN110564678B (zh) * | 2019-10-12 | 2023-04-07 | 广东唯泰生物科技有限公司 | 脐带华通氏胶间充质干细胞成骨定向分化的方法 |
| GB202003618D0 (en) | 2020-03-12 | 2020-04-29 | Univ Bristol | Gene Therapy |
| EP4342977A1 (en) * | 2022-09-26 | 2024-03-27 | Ares Trading S.A. | Serum free medium |
| WO2024091801A2 (en) * | 2022-10-13 | 2024-05-02 | President And Fellows Of Harvard College | Methods and compositions for inducing cell differentiation |
| CN119020297A (zh) * | 2024-10-22 | 2024-11-26 | 江苏凯基生物技术股份有限公司 | 一种用于人诱导多能干细胞的化学成分限定培养基 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7439064B2 (en) | 2000-03-09 | 2008-10-21 | Wicell Research Institute, Inc. | Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium |
| ATE549395T1 (de) | 2004-09-08 | 2012-03-15 | Wisconsin Alumni Res Found | Medium und kultur von embryonalen stammzellen |
| EP1962719A4 (en) * | 2005-08-29 | 2011-05-04 | Technion Res And Dev Of Foundation Ltd | MEDIA FOR BREEDING STEM CELLS |
| GB0606671D0 (en) | 2006-04-03 | 2006-05-10 | Plasso Technology Ltd | Cell Culture |
| US8513012B2 (en) * | 2008-05-02 | 2013-08-20 | Cellular Dynamics International, Inc. | Method for production of mast cells from stem cells |
| DK2356221T3 (en) * | 2008-10-24 | 2019-02-18 | Wisconsin Alumni Res Found | Pluripotent stem cells obtained by non-viral reprogramming |
| US9018010B2 (en) * | 2009-11-12 | 2015-04-28 | Technion Research & Development Foundation Limited | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
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2011
- 2011-08-05 US US13/204,354 patent/US9279103B2/en active Active
- 2011-08-05 CN CN201810229027.6A patent/CN108531444A/zh active Pending
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Non-Patent Citations (1)
| Title |
|---|
| Yao, S. et al., PNAS, 2006, 103(18): 6907-6912 |
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| WO2012019122A3 (en) | 2012-05-03 |
| JP2017018137A (ja) | 2017-01-26 |
| CA2807418A1 (en) | 2012-02-09 |
| JP6043999B2 (ja) | 2016-12-14 |
| AU2011285531A1 (en) | 2013-02-21 |
| SG187699A1 (en) | 2013-03-28 |
| KR20130099927A (ko) | 2013-09-06 |
| BR122020000909B1 (pt) | 2021-02-23 |
| IL224431A (en) | 2017-10-31 |
| DK2601288T3 (en) | 2016-05-30 |
| CN108531444A (zh) | 2018-09-14 |
| BR112013002811A8 (pt) | 2020-01-28 |
| EP2601288A2 (en) | 2013-06-12 |
| WO2012019122A2 (en) | 2012-02-09 |
| EP2601288B1 (en) | 2016-04-06 |
| US20120202291A1 (en) | 2012-08-09 |
| BR112013002811A2 (pt) | 2016-08-02 |
| US9279103B2 (en) | 2016-03-08 |
| JP2013532492A (ja) | 2013-08-19 |
| AU2011285531B2 (en) | 2015-04-30 |
| CA2807418C (en) | 2017-04-04 |
| CN103180434A (zh) | 2013-06-26 |
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