KR101799010B1 - 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 - Google Patents

히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 Download PDF

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KR101799010B1
KR101799010B1 KR1020160099508A KR20160099508A KR101799010B1 KR 101799010 B1 KR101799010 B1 KR 101799010B1 KR 1020160099508 A KR1020160099508 A KR 1020160099508A KR 20160099508 A KR20160099508 A KR 20160099508A KR 101799010 B1 KR101799010 B1 KR 101799010B1
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mmol
phenyl
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synthesis
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KR20170017792A (ko
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이재광
김윤태
이창식
송혜승
곽달용
이재영
오정택
이창곤
김일향
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주식회사 종근당
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KR1020160099508A 2015-08-04 2016-08-04 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 Active KR101799010B1 (ko)

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US (1) US10717716B2 (https=)
EP (1) EP3331864B1 (https=)
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CN (1) CN108137518B (https=)
AU (1) AU2016303891B2 (https=)
BR (1) BR112018002304B1 (https=)
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KR20220139752A (ko) * 2021-04-08 2022-10-17 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 싸이오카보닐 화합물 및 이를 포함하는 약제학적 조성물
WO2025003974A1 (en) * 2023-06-30 2025-01-02 Chong Kun Dang Pharmaceutical Corp. New preparation method of compound and new crystalline form

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MX378983B (es) 2015-05-07 2025-03-10 Chdi Foundation Inc Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos.
RU2695227C9 (ru) 2015-07-27 2020-03-04 Чонг Кун Данг Фармасьютикал Корп. Производные 1,3,4-оксадиазолсульфамида в качестве ингибитора гистондеацетилазы 6 и содержащая их фармацевтическая композиция
PL3328843T3 (pl) 2015-07-27 2023-02-27 Chong Kun Dang Pharmaceutical Corp. Związki będące pochodnymi 1,3,4 oksadiazolosulfonamidów jako inhibitor deacetylazy histonowej 6, oraz kompozycja farmaceutyczna je zawierająca
CN108026056B (zh) 2015-07-27 2021-08-03 株式会社钟根堂 作为组蛋白脱乙酰酶6抑制剂的1,3,4-噁二唑酰胺衍生物化合物及其药物组合物
JP6491393B2 (ja) 2015-08-04 2019-03-27 チョン クン ダン ファーマシューティカル コーポレーション ヒストン脱アセチル化酵素６阻害剤としての１，３，４−オキサジアゾール誘導体化合物及びこれを含有する薬剤学的組成物
JP6697074B2 (ja) * 2015-10-12 2020-05-20 チョン クン ダン ファーマシューティカル コーポレーション ヒストン脱アセチル化酵素６阻害剤としてのオキサジアゾールアミン誘導体化合物及びこれを含有する薬剤学的組成物
JP7017797B2 (ja) 2017-02-24 2022-02-09 深▲チェン▼市霊蘭生物医薬科技有限公司 新規なドーパミンｄ３受容体選択的リガンド及びびその調製方法並びに医薬使用
KR101978979B1 (ko) * 2017-02-24 2019-05-16 전남대학교산학협력단 신규한 페닐피페라진 아릴 유레아 화합물 및 이를 포함하는 약학적 조성물
WO2018165520A1 (en) 2017-03-10 2018-09-13 Vps-3, Inc. Metalloenzyme inhibitor compounds
US11207431B2 (en) * 2017-04-11 2021-12-28 The General Hospital Corporation HDAC6 inhibitors and imaging agents
CN111032651A (zh) 2017-07-31 2020-04-17 武田药品工业株式会社 杂环化合物
KR102316234B1 (ko) * 2018-07-26 2021-10-22 주식회사 종근당 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
US11945803B2 (en) 2018-08-07 2024-04-02 Tosk, Inc. Modulators of RAS GTPase
PY19106549A (es) 2018-12-21 2021-07-13 Bayer Ag 1,3,4-oxadiazoles y derivados de éstos como nuevos agentes fungicidas
WO2020159942A1 (en) 2019-01-29 2020-08-06 Tosk, Inc. Pyrazolopyrimidine modulators of ras gtpase
US12084436B2 (en) 2019-01-30 2024-09-10 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2020214537A1 (en) 2019-04-15 2020-10-22 Tosk, Inc. Modulators of ras gtpase
AU2020259100B2 (en) * 2019-04-17 2024-12-12 Fundación Kertor 1,3,4-oxadiazole derivatives as histone deacetylase inhibitors
CN110066259A (zh) * 2019-05-22 2019-07-30 南京合巨药业有限公司 一种n-环戊基-1,1-二氧代-4-硫代吗啉甲酰胺的合成方法
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