KR101774206B1 - 유도된 다능성 줄기 세포의 효율적인 확립 방법 - Google Patents
유도된 다능성 줄기 세포의 효율적인 확립 방법 Download PDFInfo
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- KR101774206B1 KR101774206B1 KR1020127004663A KR20127004663A KR101774206B1 KR 101774206 B1 KR101774206 B1 KR 101774206B1 KR 1020127004663 A KR1020127004663 A KR 1020127004663A KR 20127004663 A KR20127004663 A KR 20127004663A KR 101774206 B1 KR101774206 B1 KR 101774206B1
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- C12N2502/00—Coculture with; Conditioned medium produced by
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1361—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from dental pulp or dental follicle stem cells
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- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23240209P | 2009-08-07 | 2009-08-07 | |
| US61/232,402 | 2009-08-07 | ||
| US30730610P | 2010-02-23 | 2010-02-23 | |
| US61/307,306 | 2010-02-23 | ||
| PCT/JP2010/063733 WO2011016588A1 (en) | 2009-08-07 | 2010-08-06 | Method of efficiently establishing induced pluripotent stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120047968A KR20120047968A (ko) | 2012-05-14 |
| KR101774206B1 true KR101774206B1 (ko) | 2017-09-04 |
Family
ID=43544479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127004663A Active KR101774206B1 (ko) | 2009-08-07 | 2010-08-06 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8900871B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2462225B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5376478B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101774206B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102625837B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010279913B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2770412C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2726766T3 (cg-RX-API-DMAC7.html) |
| SG (2) | SG178197A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011016588A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2933478T3 (es) | 2005-08-03 | 2023-02-09 | Astellas Inst For Regenerative Medicine | Métodos mejorados de reprogramación de células somáticas animales |
| US20110061118A1 (en) * | 2008-03-17 | 2011-03-10 | Helmholtz Zentrum Munchen | Vectors and methods for generating vector-free induced pluripotent stem (ips) cells using site-specific recombination |
| CA2718904C (en) * | 2008-03-17 | 2017-01-03 | The Scripps Research Institute | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| CA2695590C (en) | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| KR101685209B1 (ko) * | 2008-07-30 | 2016-12-09 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| ES2645869T3 (es) | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| EP2401372A4 (en) | 2009-02-27 | 2012-09-19 | Univ Kyoto | NEW NUCLEAR REPROGRAMMING SUBSTANCE |
| KR101774206B1 (ko) | 2009-08-07 | 2017-09-04 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| US8993329B2 (en) | 2009-09-24 | 2015-03-31 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| JP5808331B2 (ja) * | 2009-10-16 | 2015-11-10 | ザ スクリプス リサーチ インスティテュート | 多能性細胞の誘導法 |
| JP5898086B2 (ja) | 2009-11-04 | 2016-04-06 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | 化学物質を用いるエピソームリプログラミング |
| WO2011102531A1 (en) | 2010-02-16 | 2011-08-25 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| WO2011119942A1 (en) * | 2010-03-25 | 2011-09-29 | Vistagen Therapeutics, Inc. | Induction of ips cells using transient episomal vectors |
| ES2624780T3 (es) | 2010-03-31 | 2017-07-17 | The Scripps Research Institute | Reprogramación de células |
| ES2685171T3 (es) | 2010-06-14 | 2018-10-05 | The Scripps Research Institute | Reprogramación de células a un nuevo destino |
| EP2582794B2 (en) | 2010-06-15 | 2024-04-24 | FUJIFILM Cellular Dynamics, Inc. | Generation of induced pluripotent stem cells from small volumes of peripheral blood |
| US9447408B2 (en) | 2010-09-14 | 2016-09-20 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| CA2814713A1 (en) * | 2010-10-14 | 2012-04-19 | University Of Central Florida Research Foundation, Inc. | Cardiac induced pluripotent stem cells and methods of use in repair and regeneration of myocardium |
| KR101975688B1 (ko) | 2010-12-22 | 2019-05-07 | 페이트 세러퓨틱스, 인코포레이티드 | 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼 |
| CN103562376B (zh) * | 2011-04-08 | 2017-12-29 | 国家医疗保健研究所 | 复壮细胞的方法 |
| WO2012137970A1 (ja) | 2011-04-08 | 2012-10-11 | 国立大学法人大阪大学 | 改変ラミニンおよびその利用 |
| US10865383B2 (en) | 2011-07-12 | 2020-12-15 | Lineage Cell Therapeutics, Inc. | Methods and formulations for orthopedic cell therapy |
| WO2013022022A1 (ja) * | 2011-08-08 | 2013-02-14 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| US20130157368A1 (en) * | 2011-12-20 | 2013-06-20 | Advanced Technologies And Regenerative Medicine, Llc | Induced pluripotent stem cells prepared from human kidney-derived cells |
| US20130157365A1 (en) * | 2011-12-20 | 2013-06-20 | Advanced Technologies And Regenerative Medicine, Llc | Induced pluripotent stem cells from human umbilical cord tissue-derived cells |
| US10155929B2 (en) * | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| US10119150B2 (en) * | 2012-05-13 | 2018-11-06 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| CA2874259C (en) * | 2012-05-23 | 2021-02-09 | Kyoto University | Highly efficient method for establishing induced pluripotent stem cell |
| CN102965393B (zh) * | 2012-11-06 | 2015-08-26 | 上海交通大学 | 人诱导多能干细胞的制备方法及其用途 |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
| WO2014192312A1 (ja) * | 2013-05-31 | 2014-12-04 | 国立大学法人 東京医科歯科大学 | 正常な内向きのカリウム電流特性を有するiPS細胞由来心筋モデル細胞 |
| US10738323B2 (en) | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| CN103571794B (zh) * | 2013-07-19 | 2016-01-20 | 中国医学科学院血液病医院(血液学研究所) | 一种抑制PUMA功能改善iPS细胞建立功效的方法 |
| CN103740756B (zh) * | 2013-12-25 | 2015-08-05 | 中国农业大学 | 一种可调控删除的非病毒游离载体及其构建方法 |
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| KR102670874B1 (ko) | 2014-03-04 | 2024-05-31 | 페이트 세러퓨틱스, 인코포레이티드 | 개선된 재프로그래밍 방법 및 세포 배양 플랫폼 |
| US10344285B2 (en) | 2014-04-09 | 2019-07-09 | Dna2.0, Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| AU2015249371B2 (en) * | 2014-04-24 | 2020-04-30 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| EP3786285A1 (en) * | 2014-06-05 | 2021-03-03 | Cedars-Sinai Medical Center | A novel and efficient method for reprogramming immortalized lymphoblastoid cell lines to induced pluripotent stem cells |
| WO2016117139A1 (ja) * | 2015-01-20 | 2016-07-28 | タカラバイオ株式会社 | 神経系細胞の製造方法 |
| US10767165B2 (en) * | 2015-01-30 | 2020-09-08 | Centre National De La Recherche Scientifique (Cnrs) | Reprogramming method for producing induced pluripotent stem cells (iPSC) |
| CA2981715A1 (en) | 2015-04-06 | 2016-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically modified guide rnas for crispr/cas-mediated gene regulation |
| EP3332020B1 (en) | 2015-08-07 | 2023-12-20 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Method of determining cellular protein homeostasis |
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| CN108291206B (zh) | 2015-09-08 | 2022-07-08 | 富士胶片细胞动力公司 | 干细胞来源的视网膜色素上皮的基于macs的纯化 |
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| CN108350429B (zh) | 2015-10-20 | 2022-02-25 | 富士胶片细胞动力公司 | 用于将多能干细胞定向分化为免疫细胞的方法 |
| CN109072198B (zh) | 2016-04-22 | 2022-08-26 | 国立大学法人京都大学 | 产多巴胺神经祖细胞的制备方法 |
| CN109641020B (zh) * | 2016-04-29 | 2022-09-02 | 复诺健生物科技加拿大有限公司 | 在癌细胞中具有增强复制的hsv载体 |
| GB201608944D0 (en) * | 2016-05-20 | 2016-07-06 | Ospedale San Raffaele And Fond Telethon | Gene Tharapy |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
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| SG10201608797WA (en) | 2016-12-29 |
| KR20120047968A (ko) | 2012-05-14 |
| EP2462225A1 (en) | 2012-06-13 |
| EP2462225A4 (en) | 2013-12-18 |
| ES2726766T3 (es) | 2019-10-09 |
| CN102625837B (zh) | 2015-01-14 |
| SG178197A1 (en) | 2012-03-29 |
| JP2013501505A (ja) | 2013-01-17 |
| AU2010279913A1 (en) | 2012-03-15 |
| EP2462225B1 (en) | 2019-03-06 |
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