KR101640801B1 - 수생 동물로부터의 콜라겐 추출물 - Google Patents

수생 동물로부터의 콜라겐 추출물 Download PDF

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KR101640801B1
KR101640801B1 KR1020117017012A KR20117017012A KR101640801B1 KR 101640801 B1 KR101640801 B1 KR 101640801B1 KR 1020117017012 A KR1020117017012 A KR 1020117017012A KR 20117017012 A KR20117017012 A KR 20117017012A KR 101640801 B1 KR101640801 B1 KR 101640801B1
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collagen
shell
obtaining
hours
papain
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KR20110119652A (ko
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자밀라 바카르
우미 하띠나 모하메드 라잘리
드줄키플라이 맷 하쉼
에이위스 쿠르니 사질리
할빈더 카우루
압둘 라만 루슬리
샴 바하린 바드리샤
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유니버시티 푸트라 말레이지아
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
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KR1020117017012A 2008-12-23 2009-08-19 수생 동물로부터의 콜라겐 추출물 Expired - Fee Related KR101640801B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MYPI20085247A MY160866A (en) 2008-12-23 2008-12-23 Collagen extraction from aquatic animals
MYPI20085247 2008-12-23

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KR20110119652A KR20110119652A (ko) 2011-11-02
KR101640801B1 true KR101640801B1 (ko) 2016-07-19

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US (2) US20120114570A1 (https=)
EP (1) EP2367847B1 (https=)
JP (2) JP5774999B2 (https=)
KR (1) KR101640801B1 (https=)
MY (1) MY160866A (https=)
WO (1) WO2010074552A1 (https=)

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JP5753356B2 (ja) * 2010-09-13 2015-07-22 株式会社龍泉堂 活性エピトープを有する非変性ｉｉ型コラーゲンの抽出方法
JP5946843B2 (ja) * 2010-12-30 2016-07-06 コリア フード リサーチ インスティチュート 超音波によりコラーゲンを抽出する方法及びその装置
TWI487711B (zh) * 2011-08-26 2015-06-11 Tci Firstech Corp 一種鮪魚膠原蛋白溶液之萃取方法及其製品
KR102080138B1 (ko) * 2012-08-23 2020-02-21 가부시키가이샤 구라게 겡큐쇼 뮤신 및 콜라겐의 분별 추출 방법
KR101971291B1 (ko) * 2012-12-07 2019-04-22 부경대학교 산학협력단 어피 단백질 가수분해물을 유효성분으로 포함하는 피부 보습 및 탄력 개선용 화장료 조성물
PL2948003T3 (pl) 2013-01-23 2021-01-25 Bottled Science Limited Kompozycja napoju poprawiająca skórę
WO2014157854A1 (ko) * 2013-03-29 2014-10-02 한국원자력연구원 방사선을 이용하여 해파리로부터 콜라겐의 분리방법
KR101514988B1 (ko) * 2013-05-01 2015-04-24 (주)청룡수산 틸라피아 비늘의 효소적 가수분해물을 포함하는 기능성 화장품 조성물
CN103320485B (zh) * 2013-06-03 2015-12-23 王南平 一种医用级生物材料用鱼皮胶原的制备方法
RU2533218C1 (ru) * 2013-07-10 2014-11-20 Яннис Сергеевич САМАРЧЕВ Способ получения коллагена из биологического материала
CN103504360B (zh) * 2013-09-12 2014-11-19 韩山师范学院 一种富含小分子胶原蛋白鱼皮即食食品的制作方法
FR3033564B1 (fr) * 2015-03-11 2021-01-29 Ys Lab Composition de collagene de peaux de poissons
JP6473024B2 (ja) * 2015-03-27 2019-02-20 株式会社ファンケル メラニン産生抑制剤
KR101669478B1 (ko) * 2015-11-23 2016-10-26 세원셀론텍(주) 콜라겐의 수득율을 높이는 방법
DE102016109094A1 (de) * 2016-05-18 2017-11-23 Gelita Ag Verfahren zur Herstellung eines Kollagenmaterials in Partikelform und hergestelltes Kollagenmaterial
FR3058142B1 (fr) * 2016-10-28 2023-11-24 Gelatines Weishardt Composition de peptides de collagene de peau de poisson et son utilisation a titre de medicament
KR101864816B1 (ko) * 2017-01-31 2018-06-05 주식회사 마린테크노 어피로부터 마린콜라겐의 추출방법
GB201708853D0 (en) * 2017-06-02 2017-07-19 Jellagen Pty Ltd Method
CN109265535A (zh) * 2017-07-17 2019-01-25 大连海洋大学 鱼皮胶原蛋白的制备方法
CN107653291A (zh) * 2017-11-15 2018-02-02 西藏央金生态农牧科技有限公司 多步酶法协同制备藏牦牛皮胶原蛋白和胶原多肽的方法
CN107960526A (zh) * 2017-11-27 2018-04-27 余雪平 胶原蛋白粉及其生产工艺
JP7157975B2 (ja) * 2018-02-06 2022-10-21 学校法人近畿大学 タンパク質溶出防止剤およびその製造方法
KR102062790B1 (ko) * 2018-05-23 2020-02-11 주식회사 라이프 투게더 황태 콜라겐 및 이의 제조방법
CN108796019A (zh) * 2018-06-28 2018-11-13 余碧芝 从北冰洋鳕鱼中提取功能性二肽胶原蛋白的方法
CN110079575A (zh) * 2019-05-27 2019-08-02 大连金荣草生物科技发展有限公司 一种提取低分子量鹿筋胶原蛋白的方法
CN110144376B (zh) * 2019-06-05 2021-04-06 北京姿美堂生物技术有限公司 纳米级胶原蛋白肽及其制备方法
KR102221221B1 (ko) * 2019-06-11 2021-03-03 농업회사법인 안동제비원전통식품(주) 참마추출물을 포함하는 피부미용 증진용 조성물 및 이를 이용한 참마 고추장
CN110272485B (zh) * 2019-06-20 2023-04-07 江苏大学 超声酸预处理辅助酸酶法提取白鲢鱼鱼皮胶原蛋白的方法
KR102406037B1 (ko) * 2019-06-27 2022-06-10 강릉원주대학교산학협력단 삼치가수분해물의 항노화 효과 및 삼치가수분해물을 포함하는 조성물
CN110760080B (zh) * 2019-10-10 2022-06-21 浙江海洋大学 一种利用鱼鳞制备保鲜膜的方法
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RU2746215C1 (ru) * 2020-05-14 2021-04-08 Анатолий Анатольевич Хитров Способ получения высокомолекулярного коллагена
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CN119119243B (zh) * 2024-11-12 2025-05-09 东阿辰康药业有限公司 一种从鱼皮中提取鱼胶原蛋白的方法及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006028138A (ja) * 2004-07-21 2006-02-02 Koken Co Ltd 魚類由来の化粧用コラーゲン溶液又は化粧用コラーゲンスポンジ
JP2006257014A (ja) * 2005-03-16 2006-09-28 National Institute For Materials Science 魚鱗由来コラーゲンおよびその取得方法
JP2007176909A (ja) 2005-12-28 2007-07-12 Rich Beauty Science:Kk コラーゲンの製造方法及び低分子コラーゲン
JP2007332161A (ja) 2007-09-07 2007-12-27 Ota Koji コラーゲン及びコラーゲン入り化粧品

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87344A (en) * 1988-08-04 1992-03-29 Univ Bar Ilan Process for the production of gelatin from fish skins
US5814328A (en) * 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
JP3979576B2 (ja) * 2002-04-10 2007-09-19 東京都 水生動物由来の無臭化コラーゲン・ゼラチン等を得る原料皮の製造法
CN1590408A (zh) * 2003-08-28 2005-03-09 南京宝生药业有限公司 河豚肽的制备工艺及其医药保健用途
JP4587711B2 (ja) * 2004-06-04 2010-11-24 ミドリホクヨー株式会社 可溶性魚コラーゲン、その製造方法及びコラーゲン化粧料
WO2007044945A2 (en) * 2005-10-13 2007-04-19 Gu, Jennifer, L. Mineral collagen chelates and methods of making and using same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006028138A (ja) * 2004-07-21 2006-02-02 Koken Co Ltd 魚類由来の化粧用コラーゲン溶液又は化粧用コラーゲンスポンジ
JP2006257014A (ja) * 2005-03-16 2006-09-28 National Institute For Materials Science 魚鱗由来コラーゲンおよびその取得方法
JP2007176909A (ja) 2005-12-28 2007-07-12 Rich Beauty Science:Kk コラーゲンの製造方法及び低分子コラーゲン
JP2007332161A (ja) 2007-09-07 2007-12-27 Ota Koji コラーゲン及びコラーゲン入り化粧品

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WO2010074552A1 (en) 2010-07-01
US9751929B2 (en) 2017-09-05
EP2367847B1 (en) 2016-10-26
US20120114570A1 (en) 2012-05-10
JP5774999B2 (ja) 2015-09-09
JP2015180622A (ja) 2015-10-15
EP2367847A1 (en) 2011-09-28
US20140147400A1 (en) 2014-05-29
KR20110119652A (ko) 2011-11-02
JP2012513461A (ja) 2012-06-14
MY160866A (en) 2017-03-31

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