KR101478933B1 - 세포 증식 질환의 치료를 위한 조성물 및 방법 - Google Patents
세포 증식 질환의 치료를 위한 조성물 및 방법 Download PDFInfo
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- KR101478933B1 KR101478933B1 KR1020137015670A KR20137015670A KR101478933B1 KR 101478933 B1 KR101478933 B1 KR 101478933B1 KR 1020137015670 A KR1020137015670 A KR 1020137015670A KR 20137015670 A KR20137015670 A KR 20137015670A KR 101478933 B1 KR101478933 B1 KR 101478933B1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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| US9562019B2 (en) | 2006-12-21 | 2017-02-07 | Sloan-Kettering Institute For Cancer Research | Substituted pyridazines as EGFR and/or KRAS inhibitors |
| US7935697B2 (en) * | 2006-12-28 | 2011-05-03 | Kinex Pharmaceuticals, Llc | Compositions for modulating a kinase cascade and methods of use thereof |
| US7939529B2 (en) | 2007-05-17 | 2011-05-10 | Kinex Pharmaceuticals, Llc | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof |
| TWI457336B (zh) | 2006-12-28 | 2014-10-21 | Kinex Pharmaceuticals Llc | 調節激酶級聯之組成物及方法 |
| US20100256147A1 (en) | 2007-04-13 | 2010-10-07 | Hangauer Jr David G | Biaryl acetamide derivatives as modulators of the kinase cascade for the treatment of hearing loss, osteoporosis and cell proliferation disorders |
| WO2009009041A2 (en) | 2007-07-06 | 2009-01-15 | Kinex Pharmaceuticals, Llc | Compositions and methods for modulating a kinase cascade |
| EP2558085B1 (en) * | 2010-04-16 | 2017-08-30 | Athenex, Inc. | Compositions and methods for the prevention and treatment of cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994027949A1 (fr) * | 1993-05-26 | 1994-12-08 | Rhone-Poulenc Rorer S.A. | Nouveaux derives de l'hydroxybiphenyle, leur preparation et les compositions pharmaceutiques qui les contiennent |
| WO2001056974A2 (en) * | 2000-02-07 | 2001-08-09 | Genzyme Corporation | Inha inhibitors and their use as antibacterials |
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