KR101095287B1 - 조혈 줄기세포 및 이를 분리하는 방법 - Google Patents

조혈 줄기세포 및 이를 분리하는 방법 Download PDF

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KR101095287B1
KR101095287B1 KR1020057001388A KR20057001388A KR101095287B1 KR 101095287 B1 KR101095287 B1 KR 101095287B1 KR 1020057001388 A KR1020057001388 A KR 1020057001388A KR 20057001388 A KR20057001388 A KR 20057001388A KR 101095287 B1 KR101095287 B1 KR 101095287B1
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KR20050027132A (ko
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프리들랜더마틴
오타니아쓰시
다실바카렌
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더 스크립스 리서치 인스티튜트
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0692—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057001388A 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 분리하는 방법 Expired - Fee Related KR101095287B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39852202P 2002-07-25 2002-07-25
US60/398,522 2002-07-25
US46705103P 2003-05-02 2003-05-02
US60/467,051 2003-05-02
PCT/US2003/024839 WO2004010959A2 (en) 2002-07-25 2003-07-25 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Related Child Applications (1)

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KR1020117020059A Division KR20110102961A (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 사용한 신생혈관 안구 질환의 치료방법

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Publication Number Publication Date
KR20050027132A KR20050027132A (ko) 2005-03-17
KR101095287B1 true KR101095287B1 (ko) 2011-12-16

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KR1020057001388A Expired - Fee Related KR101095287B1 (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 분리하는 방법
KR1020117020059A Ceased KR20110102961A (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 사용한 신생혈관 안구 질환의 치료방법

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Country Status (17)

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US (2) US7153501B2 (enExample)
EP (1) EP1542536B1 (enExample)
JP (2) JP2005538742A (enExample)
KR (2) KR101095287B1 (enExample)
CN (1) CN1307300C (enExample)
AT (1) ATE536405T1 (enExample)
AU (1) AU2003259687B2 (enExample)
BR (1) BR0312920A (enExample)
CA (1) CA2493122C (enExample)
DK (1) DK1542536T3 (enExample)
ES (1) ES2376866T3 (enExample)
MX (1) MXPA05000972A (enExample)
PL (1) PL216193B1 (enExample)
PT (1) PT1542536E (enExample)
RU (1) RU2331669C2 (enExample)
WO (2) WO2004010959A2 (enExample)
ZA (1) ZA200500682B (enExample)

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US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
WO2006031467A2 (en) * 2002-07-25 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
EP1624758A4 (en) * 2003-05-02 2007-03-07 Scripps Research Inst HEMOPOETIC STEM CELLS AND METHOD FOR THE TREATMENT OF EYE-RELATED VASCULAR DISEASES USING THESE STEM CELLS
US8088585B2 (en) * 2003-10-31 2012-01-03 Children's Medical Center Corporation Methods for purifying hematopoietic stem cells
RU2279886C2 (ru) * 2004-06-10 2006-07-20 Московский научно-исследовательский институт глазных болезней им. Гельмгольца Минздрава РФ Способ улучшения функциональной активности сетчатки при ее патологии различного генеза
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
CA2574186A1 (en) * 2004-08-13 2006-02-23 Medtronic, Inc. Isolation of endothelial progenitor cell subsets and methods for their use
JP2008512376A (ja) * 2004-09-03 2008-04-24 ザ・スクリプス・リサーチ・インステイチユート 単離された系統陰性造血幹細胞及びこれを用いた治療方法
DE102004055615A1 (de) * 2004-11-16 2006-05-18 Universitätsklinikum Hamburg-Eppendorf In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung
US20070231306A1 (en) * 2005-02-24 2007-10-04 The Scripps Research Institute Isolated myeloid-like cell populations and methods of treatment therewith
CA2599139A1 (en) * 2005-02-24 2006-08-31 The Scripps Research Institute Revascularization of ischemic retinal tissue and screening method therefor
JP2008537478A (ja) * 2005-02-24 2008-09-18 ザ・スクリプス・リサーチ・インステイチユート 単離骨髄球様骨髄細胞集団及びそれを用いた治療方法
JP5173442B2 (ja) * 2005-02-24 2013-04-03 ザ スクリプス リサーチ インスティチュート 未熟児網膜症及び関連網膜症疾患の治療のための方法
JP4734636B2 (ja) * 2005-11-02 2011-07-27 国立大学法人 鹿児島大学 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法
DK2441461T3 (da) 2005-11-07 2014-07-28 Amorcyte Inc Sammensætninger og fremgangsmåder til reparation af vaskulær skade
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
AP2949A (en) 2006-03-07 2014-07-31 Shroff Geeta Compositions comprising human embryonic stem cellsand their derivatives, methods of use, and method s of preparation
KR100757265B1 (ko) * 2006-04-27 2007-09-10 (주) 차바이오텍 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물
US20100111910A1 (en) * 2006-07-12 2010-05-06 Angioblast Systems, Inc. Treatment of excessive neovascularization
SG176460A1 (en) * 2006-11-07 2011-12-29 Pervasis Therapeutics Inc Materials and methods for treating and managing angiogenesis-mediated diseases
US20100098675A1 (en) * 2008-05-30 2010-04-22 Nikolai Tankovich Methods for reducing the side effects of ophthalmic laser surgery
RU2535966C2 (ru) * 2008-09-12 2014-12-20 Криопрашис Криобиоложия Лтда. Клеточная терапия ишемической ткани
WO2010065601A1 (en) 2008-12-03 2010-06-10 Amorcyte, Inc. Infarct area perfusion-improving compositions and methods of vascular injury repair
RU2428956C2 (ru) * 2009-07-13 2011-09-20 Александр Дмитриевич Ромащенко Способ лечения атрофии зрительного нерва посредством трансплантации аутологичных стволовых клеток
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Also Published As

Publication number Publication date
EP1542536B1 (en) 2011-12-07
US7153501B2 (en) 2006-12-26
RU2005105065A (ru) 2005-09-10
ATE536405T1 (de) 2011-12-15
CA2493122A1 (en) 2004-02-05
CN1688196A (zh) 2005-10-26
WO2004010959A2 (en) 2004-02-05
KR20110102961A (ko) 2011-09-19
WO2004010959A3 (en) 2005-04-07
EP1542536A4 (en) 2007-05-16
PL216193B1 (pl) 2014-03-31
JP2010285434A (ja) 2010-12-24
US20040197902A1 (en) 2004-10-07
BR0312920A (pt) 2007-07-10
JP2005538742A (ja) 2005-12-22
US20070116685A1 (en) 2007-05-24
CN1307300C (zh) 2007-03-28
AU2003259687B2 (en) 2009-10-29
ES2376866T3 (es) 2012-03-20
AU2003259687A1 (en) 2004-02-16
MXPA05000972A (es) 2005-09-12
PL374868A1 (en) 2005-11-14
CA2493122C (en) 2012-11-27
KR20050027132A (ko) 2005-03-17
WO2004098499A3 (en) 2005-10-06
ZA200500682B (en) 2006-07-26
WO2004098499A2 (en) 2004-11-18
DK1542536T3 (da) 2012-01-23
EP1542536A2 (en) 2005-06-22
RU2331669C2 (ru) 2008-08-20
JP5385219B2 (ja) 2014-01-08
PT1542536E (pt) 2012-02-14

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