ATE536405T1 - Hämatopoetische stammzellen und verfahren zur behandlung von neovaskulären augenerkrankungen damit - Google Patents

Hämatopoetische stammzellen und verfahren zur behandlung von neovaskulären augenerkrankungen damit

Info

Publication number
ATE536405T1
ATE536405T1 AT03772195T AT03772195T ATE536405T1 AT E536405 T1 ATE536405 T1 AT E536405T1 AT 03772195 T AT03772195 T AT 03772195T AT 03772195 T AT03772195 T AT 03772195T AT E536405 T1 ATE536405 T1 AT E536405T1
Authority
AT
Austria
Prior art keywords
cells
stem cells
eye diseases
express
hematopoetic stem
Prior art date
Application number
AT03772195T
Other languages
English (en)
Inventor
Martin Friedlander
Atsushi Otani
Karen Dasilva
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE536405T1 publication Critical patent/ATE536405T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/069Vascular Endothelial cells
    • C12N5/0692Stem cells; Progenitor cells; Precursor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03772195T 2002-07-25 2003-07-25 Hämatopoetische stammzellen und verfahren zur behandlung von neovaskulären augenerkrankungen damit ATE536405T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39852202P 2002-07-25 2002-07-25
US46705103P 2003-05-02 2003-05-02
PCT/US2003/024839 WO2004010959A2 (en) 2002-07-25 2003-07-25 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Publications (1)

Publication Number Publication Date
ATE536405T1 true ATE536405T1 (de) 2011-12-15

Family

ID=31191212

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03772195T ATE536405T1 (de) 2002-07-25 2003-07-25 Hämatopoetische stammzellen und verfahren zur behandlung von neovaskulären augenerkrankungen damit

Country Status (17)

Country Link
US (2) US7153501B2 (de)
EP (1) EP1542536B1 (de)
JP (2) JP2005538742A (de)
KR (2) KR20110102961A (de)
CN (1) CN1307300C (de)
AT (1) ATE536405T1 (de)
AU (1) AU2003259687B2 (de)
BR (1) BR0312920A (de)
CA (1) CA2493122C (de)
DK (1) DK1542536T3 (de)
ES (1) ES2376866T3 (de)
MX (1) MXPA05000972A (de)
PL (1) PL216193B1 (de)
PT (1) PT1542536E (de)
RU (1) RU2331669C2 (de)
WO (2) WO2004010959A2 (de)
ZA (1) ZA200500682B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
WO2006031467A2 (en) * 2002-07-25 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
AU2004237749B2 (en) * 2003-05-02 2011-09-15 The Scipps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
WO2005042731A1 (en) * 2003-10-31 2005-05-12 Children's Medical Center Corporation Methods for purifying hematopoietic stem cells
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
DE602005012962D1 (de) * 2004-08-13 2009-04-09 Medtronic Inc Isolation der endothelvorläuferzellen-untermengen und verfahren zu ihrer verwendung
CA2579292A1 (en) * 2004-09-03 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
DE102004055615A1 (de) * 2004-11-16 2006-05-18 Universitätsklinikum Hamburg-Eppendorf In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung
RU2418856C2 (ru) * 2005-02-24 2011-05-20 Дзе Скриппс Рисерч Инститьют Изолированные популяции миелоидоподобных клеток костного мозга и способы лечения с ними
CN101356268A (zh) * 2005-02-24 2009-01-28 斯克里普斯研究学院 未熟儿视网膜病和相关视网膜疾病的治疗方法
US20070231306A1 (en) * 2005-02-24 2007-10-04 The Scripps Research Institute Isolated myeloid-like cell populations and methods of treatment therewith
MX2007010384A (es) * 2005-02-24 2007-10-18 Scripps Research Inst Revascularizacion de tejido retinado isquemico y metodo de seleccion para el mismo.
JP4734636B2 (ja) * 2005-11-02 2011-07-27 国立大学法人 鹿児島大学 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法
DK2441461T3 (da) 2005-11-07 2014-07-28 Amorcyte Inc Sammensætninger og fremgangsmåder til reparation af vaskulær skade
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
US9034316B2 (en) 2006-10-24 2015-05-19 Amorcyte, Llc Infarct area perfusion-improving compositions and methods of vascular injury repair
EP2422799A3 (de) 2006-03-07 2013-03-06 Geeta Shroff Zusammensetzungen enhaltend menschliche embryonale Stammzellen und ihre Derivate, Verwendung davon und Verfahren zur ihrer Vorbereitung
KR100757265B1 (ko) * 2006-04-27 2007-09-10 (주) 차바이오텍 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물
AU2007272313B2 (en) * 2006-07-12 2013-11-21 Mesoblast, Inc. Treatment of excessive neovascularization
CN103230414A (zh) * 2006-11-07 2013-08-07 夏尔再生医学公司 用于治疗和控制血管生成介导的疾病的材料和方法
US20100098675A1 (en) * 2008-05-30 2010-04-22 Nikolai Tankovich Methods for reducing the side effects of ophthalmic laser surgery
BRPI0919020A2 (pt) * 2008-09-12 2017-08-22 Univ South Florida Uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris
WO2012005763A1 (en) 2010-07-06 2012-01-12 The Scripps Research Institute Use of myeloid-like progenitor cell populations to treat tumors
RU2664673C2 (ru) 2011-10-27 2018-08-21 Веллстат Офтэлмикс Корпорэйшн Векторы, кодирующие фактор жизнеспособности колбочек, полученный из палочек
KR20150009541A (ko) * 2012-04-16 2015-01-26 더 리전트 오브 더 유니버시티 오브 캘리포니아 배아 줄기 세포 미소낭포를 이용한 안구 치료법
CA2882802C (en) * 2012-08-24 2021-07-06 Riken Method for producing retinal pigment epithelial cell sheet
CN113498347B (zh) * 2019-02-28 2024-02-02 深圳大学 内皮祖细胞(epc)在治疗早衰综合症疾病的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908763B1 (en) * 1997-08-22 2005-06-21 The Board Of Trustees Of The Leland Stanford Junior University Mammalian common lymphoid progenitor cell
AU3719799A (en) * 1998-04-28 1999-11-16 Nycomed Imaging As Improvements in or relating to separation processes
US6767737B1 (en) * 1998-08-31 2004-07-27 New York University Stem cells bearing an FGF receptor on the cell surface
US6780627B1 (en) * 2000-01-31 2004-08-24 Millennium Pharmaceuticals, Inc. 22438, 23553, 25278, and 26212 novel human sulfatases
US20020098167A1 (en) * 2000-07-31 2002-07-25 Piero Anversa Methods and compositions for the repair and/or regeneration of damaged myocardium
ATE420653T1 (de) * 2001-02-23 2009-01-15 Scripps Research Inst Von tryptophanyl-trna-synthetase stammende polypeptide zur regulierung der angiogenese
AU2003224712A1 (en) * 2002-03-21 2003-10-08 University Of Florida Modulating angiogenesis
AU2003256446A1 (en) * 2002-07-05 2004-01-23 Roger Williams Medical Center Targeting and tracking of cells to specific organs and tissues in vivo

Also Published As

Publication number Publication date
KR101095287B1 (ko) 2011-12-16
AU2003259687A1 (en) 2004-02-16
EP1542536A2 (de) 2005-06-22
US20070116685A1 (en) 2007-05-24
KR20050027132A (ko) 2005-03-17
ES2376866T3 (es) 2012-03-20
WO2004010959A2 (en) 2004-02-05
CA2493122C (en) 2012-11-27
MXPA05000972A (es) 2005-09-12
JP2005538742A (ja) 2005-12-22
DK1542536T3 (da) 2012-01-23
RU2331669C2 (ru) 2008-08-20
CA2493122A1 (en) 2004-02-05
PL374868A1 (en) 2005-11-14
WO2004098499A2 (en) 2004-11-18
CN1307300C (zh) 2007-03-28
AU2003259687B2 (en) 2009-10-29
EP1542536A4 (de) 2007-05-16
WO2004010959A3 (en) 2005-04-07
WO2004098499A3 (en) 2005-10-06
EP1542536B1 (de) 2011-12-07
US20040197902A1 (en) 2004-10-07
CN1688196A (zh) 2005-10-26
JP2010285434A (ja) 2010-12-24
US7153501B2 (en) 2006-12-26
PT1542536E (pt) 2012-02-14
RU2005105065A (ru) 2005-09-10
PL216193B1 (pl) 2014-03-31
BR0312920A (pt) 2007-07-10
JP5385219B2 (ja) 2014-01-08
ZA200500682B (en) 2006-07-26
KR20110102961A (ko) 2011-09-19

Similar Documents

Publication Publication Date Title
ATE536405T1 (de) Hämatopoetische stammzellen und verfahren zur behandlung von neovaskulären augenerkrankungen damit
Pellegrini et al. The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin1
Ogawa The importance of adipose-derived stem cells and vascularized tissue regeneration in the field of tissue transplantation
MOHY et al. Autologous in vitro expanded mesenchymal stem cell therapy for human old myocardial infarction
Schmitt et al. Application of stem cells in orthopedics
Altaie et al. Use of platelet lysate for bone regeneration-are we ready for clinical translation?
Prins et al. Bone-forming capacity of mesenchymal stromal cells when cultured in the presence of human platelet lysate as substitute for fetal bovine serum
DE69837491D1 (de) Menschliche mesenchymale stammzellen aus peripherem blut
Takaku et al. In vivo cell tracking by bioluminescence imaging after transplantation of bioengineered cell sheets to the knee joint
Carballo et al. Cell-based approaches for augmentation of tendon repair
Morimoto et al. The rapid inactivation of porcine skin by applying high hydrostatic pressure without damaging the extracellular matrix
Tevlin et al. A novel method of human adipose-derived stem cell isolation with resultant increased cell yield
Al-Qadhi et al. The gingiva from the tissue surrounding the bone to the tissue regenerating the bone: a systematic review of the osteogenic capacity of gingival mesenchymal stem cells in preclinical studies
Imran et al. Regenerative medicine therapy in Malaysia: an update
Orbay et al. Comparison of endothelial differentiation capacities of human and rat adipose-derived stem cells
Cieśla et al. Cadaveric stem cells: their research potential and limitations
WO2006031467A3 (en) Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
Gesslbauer et al. The regenerative capability of the urodele amphibians and its potential for plastic surgery
Hung Effects of hypoxic culture on bone marrow mesenchymal stem cells: from bench to bedside
Müller et al. Current stem cells technologies used in medicine
MXPA05011752A (es) Celulas madre hematopoyeticas y metodos de tratamiento de enfermedades oculares neovasculares con las mismas.
Marashi et al. On the role of oxygen and glucose in bone marrow-derived mesenchymal stem cell proliferation
Ceci et al. Does Freeze–Thawing Influence the Effects of Platelet Concentrates? An In Vitro Study on Human Adipose-Derived Stem Cells
Steele et al. Temporal Control over Macrophage Phenotype and the Host Response via Magnetically Actuated Scaffolds
Gratzer et al. A new decellularized dermal matrix: superior properties and in-vivo performance when compared with the leading commercial product