DK1542536T3 - Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed - Google Patents
Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermedInfo
- Publication number
- DK1542536T3 DK1542536T3 DK03772195.8T DK03772195T DK1542536T3 DK 1542536 T3 DK1542536 T3 DK 1542536T3 DK 03772195 T DK03772195 T DK 03772195T DK 1542536 T3 DK1542536 T3 DK 1542536T3
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- hematopoietic stem
- methods
- stem cells
- eye diseases
- Prior art date
Links
- 210000003958 hematopoietic stem cell Anatomy 0.000 title abstract 2
- 208000030533 eye disease Diseases 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- 108010053099 Vascular Endothelial Growth Factor Receptor-2 Proteins 0.000 abstract 2
- 210000001210 retinal vessel Anatomy 0.000 abstract 2
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 abstract 1
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 abstract 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 abstract 1
- 102000016549 Vascular Endothelial Growth Factor Receptor-2 Human genes 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 230000003511 endothelial effect Effects 0.000 abstract 1
- 210000001525 retina Anatomy 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 210000005166 vasculature Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39852202P | 2002-07-25 | 2002-07-25 | |
| US46705103P | 2003-05-02 | 2003-05-02 | |
| PCT/US2003/024839 WO2004010959A2 (en) | 2002-07-25 | 2003-07-25 | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1542536T3 true DK1542536T3 (da) | 2012-01-23 |
Family
ID=31191212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03772195.8T DK1542536T3 (da) | 2002-07-25 | 2003-07-25 | Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7153501B2 (enExample) |
| EP (1) | EP1542536B1 (enExample) |
| JP (2) | JP2005538742A (enExample) |
| KR (2) | KR101095287B1 (enExample) |
| CN (1) | CN1307300C (enExample) |
| AT (1) | ATE536405T1 (enExample) |
| AU (1) | AU2003259687B2 (enExample) |
| BR (1) | BR0312920A (enExample) |
| CA (1) | CA2493122C (enExample) |
| DK (1) | DK1542536T3 (enExample) |
| ES (1) | ES2376866T3 (enExample) |
| MX (1) | MXPA05000972A (enExample) |
| PL (1) | PL216193B1 (enExample) |
| PT (1) | PT1542536E (enExample) |
| RU (1) | RU2331669C2 (enExample) |
| WO (2) | WO2004010959A2 (enExample) |
| ZA (1) | ZA200500682B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006031467A2 (en) * | 2002-07-25 | 2006-03-23 | The Scripps Research Institute | Isolated lineage negative hematopoietic stem cells and methods of treatment therewith |
| US20060104963A1 (en) * | 2002-07-25 | 2006-05-18 | The Scripps Research Institute | Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells |
| US20060104962A1 (en) * | 2002-07-25 | 2006-05-18 | The Scripps Research Institute | Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
| CA2524063C (en) * | 2003-05-02 | 2015-02-17 | The Scripps Research Institute | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
| US8088585B2 (en) * | 2003-10-31 | 2012-01-03 | Children's Medical Center Corporation | Methods for purifying hematopoietic stem cells |
| RU2279886C2 (ru) * | 2004-06-10 | 2006-07-20 | Московский научно-исследовательский институт глазных болезней им. Гельмгольца Минздрава РФ | Способ улучшения функциональной активности сетчатки при ее патологии различного генеза |
| US8282921B2 (en) | 2004-08-02 | 2012-10-09 | Paul Glidden | tRNA synthetase fragments |
| JP2008509678A (ja) * | 2004-08-13 | 2008-04-03 | メドトロニック・インコーポレーテッド | 内皮前駆細胞サブセットの単離とそれらの使用方法 |
| EP1802199A4 (en) * | 2004-09-03 | 2008-08-27 | Scripps Research Inst | HEMATOPOIETIC STEM CELLS OF ISOLATED NEGATIVE LINES AND METHODS OF TREATMENT THEREOF |
| DE102004055615A1 (de) * | 2004-11-16 | 2006-05-18 | Universitätsklinikum Hamburg-Eppendorf | In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung |
| US20080193435A1 (en) * | 2005-02-24 | 2008-08-14 | Martin Friedlander | Revascularization of Ischemic Retinal Tissue and Screening Method Therefor |
| RU2403906C2 (ru) * | 2005-02-24 | 2010-11-20 | Дзе Скриппс Рисерч Инститьют | Способ лечения ретинопатии при недоношенности и родственных ретинопатических заболеваний |
| RU2418856C2 (ru) * | 2005-02-24 | 2011-05-20 | Дзе Скриппс Рисерч Инститьют | Изолированные популяции миелоидоподобных клеток костного мозга и способы лечения с ними |
| US20070231306A1 (en) * | 2005-02-24 | 2007-10-04 | The Scripps Research Institute | Isolated myeloid-like cell populations and methods of treatment therewith |
| JP4734636B2 (ja) * | 2005-11-02 | 2011-07-27 | 国立大学法人 鹿児島大学 | 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法 |
| US8637005B2 (en) | 2005-11-07 | 2014-01-28 | Amorcyte, Inc. | Compositions and methods of vascular injury repair |
| WO2007055905A2 (en) | 2005-11-07 | 2007-05-18 | Amorcyte, Inc. | Compositions and methods of vascular injury repair |
| US20110076255A1 (en) | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
| GEP20135796B (en) | 2006-03-07 | 2013-04-10 | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation | |
| KR100757265B1 (ko) * | 2006-04-27 | 2007-09-10 | (주) 차바이오텍 | 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물 |
| AU2007272313B2 (en) * | 2006-07-12 | 2013-11-21 | Mesoblast, Inc. | Treatment of excessive neovascularization |
| CN101583367B (zh) * | 2006-11-07 | 2013-05-01 | 夏尔再生医学公司 | 用于治疗和控制血管生成介导的疾病的材料和方法 |
| US20100098675A1 (en) * | 2008-05-30 | 2010-04-22 | Nikolai Tankovich | Methods for reducing the side effects of ophthalmic laser surgery |
| CA2737193A1 (en) * | 2008-09-12 | 2010-03-18 | Universidade Federal De Sao Paulo - Unifesp | Ischemic tissue cell therapy |
| BRPI0920976A2 (pt) | 2008-12-03 | 2015-08-18 | Amorcyte Inc | Composições que melhoram a perfusão da area de infarto e metodos de restauração da lesão vascular. |
| RU2428956C2 (ru) * | 2009-07-13 | 2011-09-20 | Александр Дмитриевич Ромащенко | Способ лечения атрофии зрительного нерва посредством трансплантации аутологичных стволовых клеток |
| WO2012005763A1 (en) | 2010-07-06 | 2012-01-12 | The Scripps Research Institute | Use of myeloid-like progenitor cell populations to treat tumors |
| CN110777124A (zh) | 2011-10-27 | 2020-02-11 | 威尔斯达眼科制剂公司 | 编码视杆细胞来源的视锥细胞活力因子的载体 |
| WO2013158258A1 (en) * | 2012-04-16 | 2013-10-24 | The Regents Of The University Of California | Ocular therapeutics using embryonic system cell microvesicles |
| US11033586B2 (en) | 2012-08-24 | 2021-06-15 | Riken | Method for producing retinal pigment epithelial cell sheet |
| CN113498347B (zh) * | 2019-02-28 | 2024-02-02 | 深圳大学 | 内皮祖细胞(epc)在治疗早衰综合症疾病的用途 |
| CN121550400B (zh) * | 2026-01-26 | 2026-05-19 | 天津医科大学眼科医院 | Crybb2重组蛋白在治疗和/或预防糖尿病性视网膜病变中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA27055C2 (uk) * | 1993-12-14 | 2000-02-28 | Центр Ембріональних Тканин "Емселл" | Лікарський препарат імуhозаміhhої дії hа осhові клітиhhої суспеhзії та спосіб лікуваhhя сиhдрому hабутого імуhодефіциту (віл-іhфекції) з використаhhям цього препарату |
| US6908763B1 (en) * | 1997-08-22 | 2005-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian common lymphoid progenitor cell |
| WO1999055837A2 (en) * | 1998-04-28 | 1999-11-04 | Nycomed Imaging As | Improvements in or relating to separation processes |
| US6767737B1 (en) * | 1998-08-31 | 2004-07-27 | New York University | Stem cells bearing an FGF receptor on the cell surface |
| US6780627B1 (en) * | 2000-01-31 | 2004-08-24 | Millennium Pharmaceuticals, Inc. | 22438, 23553, 25278, and 26212 novel human sulfatases |
| WO2002009650A2 (en) * | 2000-07-31 | 2002-02-07 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| CN100486992C (zh) * | 2001-02-23 | 2009-05-13 | 斯克里普斯研究学院 | 用于调节血管发生的色氨酰-tRNA合成酶衍生的多肽 |
| WO2003080116A1 (en) * | 2002-03-21 | 2003-10-02 | University Of Florida | Modulating angiogenesis |
| WO2004005531A2 (en) * | 2002-07-05 | 2004-01-15 | Roger Williams Medical Center | Targeting and tracking of cells to specific organs and tissues in vivo |
-
2003
- 2003-07-25 CN CNB038177358A patent/CN1307300C/zh not_active Expired - Fee Related
- 2003-07-25 CA CA2493122A patent/CA2493122C/en not_active Expired - Fee Related
- 2003-07-25 JP JP2005505648A patent/JP2005538742A/ja active Pending
- 2003-07-25 PL PL374868A patent/PL216193B1/pl unknown
- 2003-07-25 US US10/628,783 patent/US7153501B2/en not_active Expired - Fee Related
- 2003-07-25 EP EP03772195A patent/EP1542536B1/en not_active Expired - Lifetime
- 2003-07-25 ES ES03772195T patent/ES2376866T3/es not_active Expired - Lifetime
- 2003-07-25 BR BRPI0312920-9A patent/BR0312920A/pt not_active IP Right Cessation
- 2003-07-25 WO PCT/US2003/024839 patent/WO2004010959A2/en not_active Ceased
- 2003-07-25 KR KR1020057001388A patent/KR101095287B1/ko not_active Expired - Fee Related
- 2003-07-25 KR KR1020117020059A patent/KR20110102961A/ko not_active Ceased
- 2003-07-25 AU AU2003259687A patent/AU2003259687B2/en not_active Ceased
- 2003-07-25 PT PT03772195T patent/PT1542536E/pt unknown
- 2003-07-25 RU RU2005105065/13A patent/RU2331669C2/ru not_active IP Right Cessation
- 2003-07-25 DK DK03772195.8T patent/DK1542536T3/da active
- 2003-07-25 MX MXPA05000972A patent/MXPA05000972A/es active IP Right Grant
- 2003-07-25 AT AT03772195T patent/ATE536405T1/de active
-
2004
- 2004-04-28 WO PCT/US2004/012989 patent/WO2004098499A2/en not_active Ceased
-
2005
- 2005-01-24 ZA ZA200500682A patent/ZA200500682B/xx unknown
-
2006
- 2006-12-20 US US11/643,571 patent/US20070116685A1/en not_active Abandoned
-
2010
- 2010-06-23 JP JP2010142292A patent/JP5385219B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1542536A2 (en) | 2005-06-22 |
| MXPA05000972A (es) | 2005-09-12 |
| AU2003259687A1 (en) | 2004-02-16 |
| JP2010285434A (ja) | 2010-12-24 |
| PL374868A1 (en) | 2005-11-14 |
| KR101095287B1 (ko) | 2011-12-16 |
| RU2331669C2 (ru) | 2008-08-20 |
| PT1542536E (pt) | 2012-02-14 |
| CA2493122A1 (en) | 2004-02-05 |
| BR0312920A (pt) | 2007-07-10 |
| JP5385219B2 (ja) | 2014-01-08 |
| RU2005105065A (ru) | 2005-09-10 |
| WO2004010959A3 (en) | 2005-04-07 |
| CN1688196A (zh) | 2005-10-26 |
| US7153501B2 (en) | 2006-12-26 |
| WO2004098499A2 (en) | 2004-11-18 |
| US20040197902A1 (en) | 2004-10-07 |
| WO2004098499A3 (en) | 2005-10-06 |
| CA2493122C (en) | 2012-11-27 |
| JP2005538742A (ja) | 2005-12-22 |
| ATE536405T1 (de) | 2011-12-15 |
| KR20050027132A (ko) | 2005-03-17 |
| ES2376866T3 (es) | 2012-03-20 |
| CN1307300C (zh) | 2007-03-28 |
| EP1542536A4 (en) | 2007-05-16 |
| WO2004010959A2 (en) | 2004-02-05 |
| KR20110102961A (ko) | 2011-09-19 |
| AU2003259687B2 (en) | 2009-10-29 |
| ZA200500682B (en) | 2006-07-26 |
| EP1542536B1 (en) | 2011-12-07 |
| US20070116685A1 (en) | 2007-05-24 |
| PL216193B1 (pl) | 2014-03-31 |
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