DK1542536T3 - Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed - Google Patents

Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed

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Publication number
DK1542536T3
DK1542536T3 DK03772195.8T DK03772195T DK1542536T3 DK 1542536 T3 DK1542536 T3 DK 1542536T3 DK 03772195 T DK03772195 T DK 03772195T DK 1542536 T3 DK1542536 T3 DK 1542536T3
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DK
Denmark
Prior art keywords
cells
hematopoietic stem
methods
stem cells
eye diseases
Prior art date
Application number
DK03772195.8T
Other languages
English (en)
Inventor
Martin Friedlander
Atsushi Otani
Karen Dasilva
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK1542536T3 publication Critical patent/DK1542536T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0692—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
DK03772195.8T 2002-07-25 2003-07-25 Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed DK1542536T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39852202P 2002-07-25 2002-07-25
US46705103P 2003-05-02 2003-05-02
PCT/US2003/024839 WO2004010959A2 (en) 2002-07-25 2003-07-25 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Publications (1)

Publication Number Publication Date
DK1542536T3 true DK1542536T3 (da) 2012-01-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK03772195.8T DK1542536T3 (da) 2002-07-25 2003-07-25 Hæmatopoietiske stamceller og fremgangsmåder til behandling af neovaskulære øjensygdomme dermed

Country Status (17)

Country Link
US (2) US7153501B2 (da)
EP (1) EP1542536B1 (da)
JP (2) JP2005538742A (da)
KR (2) KR101095287B1 (da)
CN (1) CN1307300C (da)
AT (1) ATE536405T1 (da)
AU (1) AU2003259687B2 (da)
BR (1) BR0312920A (da)
CA (1) CA2493122C (da)
DK (1) DK1542536T3 (da)
ES (1) ES2376866T3 (da)
MX (1) MXPA05000972A (da)
PL (1) PL216193B1 (da)
PT (1) PT1542536E (da)
RU (1) RU2331669C2 (da)
WO (2) WO2004010959A2 (da)
ZA (1) ZA200500682B (da)

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WO2006031467A2 (en) * 2002-07-25 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
KR101169261B1 (ko) * 2003-05-02 2012-08-03 더 스크립스 리서치 인스티튜트 조혈 줄기세포 및 이를 포함하는 약제학적 조성물
US8088585B2 (en) * 2003-10-31 2012-01-03 Children's Medical Center Corporation Methods for purifying hematopoietic stem cells
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
US20060035290A1 (en) * 2004-08-13 2006-02-16 Medtronic, Inc. Isolation of endothelial progenitor cell subsets and methods for their use
MX2007002639A (es) * 2004-09-03 2007-08-06 Scripps Research Inst Celulas madre hematopoyeticas de linaje negativo aisladas y metodos de tratamiento con las mismas.
DE102004055615A1 (de) * 2004-11-16 2006-05-18 Universitätsklinikum Hamburg-Eppendorf In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung
EP1935976B1 (en) * 2005-02-24 2012-02-15 The Scripps Research Institute Transfected myeloid-like cells for the treatment of retinopathy of prematurity and related diseases
US20070231306A1 (en) * 2005-02-24 2007-10-04 The Scripps Research Institute Isolated myeloid-like cell populations and methods of treatment therewith
AU2006229687B2 (en) * 2005-02-24 2011-08-11 The Scripps Research Institute Isolated myeloid-like bone marrow cell populations and methods of treatment therewith
CA2599139A1 (en) * 2005-02-24 2006-08-31 The Scripps Research Institute Revascularization of ischemic retinal tissue and screening method therefor
JP4734636B2 (ja) * 2005-11-02 2011-07-27 国立大学法人 鹿児島大学 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
ES2485387T3 (es) 2005-11-07 2014-08-13 Amorcyte, Inc. Composiciones y métodos de reparación de lesiones vasculares
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
DK1993575T3 (da) 2006-03-07 2019-10-14 Geeta Shroff Sammensætninger omfattende humane embryostamceller og derivater deraf, fremgangsmåder til anvendelse og fremgangsmåder til fremstilling
KR100757265B1 (ko) * 2006-04-27 2007-09-10 (주) 차바이오텍 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물
JP6041456B2 (ja) * 2006-07-12 2016-12-07 メゾブラスト，インコーポレーテッド 過剰新生血管形成の治療
CA2668621A1 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Materials and methods for treating and managing angiogenesis-mediated diseases
US20100098675A1 (en) * 2008-05-30 2010-04-22 Nikolai Tankovich Methods for reducing the side effects of ophthalmic laser surgery
CN102186970A (zh) * 2008-09-12 2011-09-14 克里奥普拉斯低温生物有限公司 缺血性组织的细胞疗法
RU2497532C2 (ru) 2008-12-03 2013-11-10 Эморсайт, Инк. Композиции, улучшающие перфузию в области инфаркта и способы восстановления сосудистого повреждения
WO2012005763A1 (en) 2010-07-06 2012-01-12 The Scripps Research Institute Use of myeloid-like progenitor cell populations to treat tumors
EP2797613B1 (en) 2011-10-27 2019-12-04 Wellstat Ophthalmics Corporation Vectors encoding rod-derived cone viability factor
AU2013249786A1 (en) * 2012-04-16 2014-11-06 The Regents Of The University Of California Ocular therapeutics using embryonic stem cell microvesicles
SG11201501319PA (en) * 2012-08-24 2015-04-29 Riken Method for producing retinal pigment epithelial cell sheet
WO2020172854A1 (en) * 2019-02-28 2020-09-03 Shenzhen University Use of endothelial progenitor cells (epcs) in rejuvenating microvasculature, preventing aging and treating age-related diseases

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US6908763B1 (en) * 1997-08-22 2005-06-21 The Board Of Trustees Of The Leland Stanford Junior University Mammalian common lymphoid progenitor cell
IL139034A0 (en) * 1998-04-28 2001-11-25 Nycomed Imaging As Improvements in or relating to separation processes
US6767737B1 (en) * 1998-08-31 2004-07-27 New York University Stem cells bearing an FGF receptor on the cell surface
US6780627B1 (en) * 2000-01-31 2004-08-24 Millennium Pharmaceuticals, Inc. 22438, 23553, 25278, and 26212 novel human sulfatases
US20020098167A1 (en) * 2000-07-31 2002-07-25 Piero Anversa Methods and compositions for the repair and/or regeneration of damaged myocardium
AU2002306558B2 (en) * 2001-02-23 2007-06-28 The Scripps Research Institute Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiogenesis
AU2003224712A1 (en) * 2002-03-21 2003-10-08 University Of Florida Modulating angiogenesis
AU2003256446A1 (en) * 2002-07-05 2004-01-23 Roger Williams Medical Center Targeting and tracking of cells to specific organs and tissues in vivo

Also Published As

Publication number Publication date
EP1542536A4 (en) 2007-05-16
RU2005105065A (ru) 2005-09-10
KR20110102961A (ko) 2011-09-19
ES2376866T3 (es) 2012-03-20
CA2493122A1 (en) 2004-02-05
KR20050027132A (ko) 2005-03-17
ZA200500682B (en) 2006-07-26
WO2004098499A2 (en) 2004-11-18
WO2004098499A3 (en) 2005-10-06
RU2331669C2 (ru) 2008-08-20
JP2005538742A (ja) 2005-12-22
PT1542536E (pt) 2012-02-14
ATE536405T1 (de) 2011-12-15
US7153501B2 (en) 2006-12-26
JP5385219B2 (ja) 2014-01-08
PL216193B1 (pl) 2014-03-31
EP1542536A2 (en) 2005-06-22
BR0312920A (pt) 2007-07-10
CN1307300C (zh) 2007-03-28
MXPA05000972A (es) 2005-09-12
JP2010285434A (ja) 2010-12-24
US20040197902A1 (en) 2004-10-07
AU2003259687A1 (en) 2004-02-16
CA2493122C (en) 2012-11-27
WO2004010959A2 (en) 2004-02-05
CN1688196A (zh) 2005-10-26
WO2004010959A3 (en) 2005-04-07
US20070116685A1 (en) 2007-05-24
PL374868A1 (en) 2005-11-14
AU2003259687B2 (en) 2009-10-29
EP1542536B1 (en) 2011-12-07
KR101095287B1 (ko) 2011-12-16

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