KR100920599B1 - 작용기를 함유하지 않는 폴리아크릴레이트 접촉 결합 접착제에 기초한 경피 제제 - Google Patents

작용기를 함유하지 않는 폴리아크릴레이트 접촉 결합 접착제에 기초한 경피 제제 Download PDF

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Publication number
KR100920599B1
KR100920599B1 KR1020047002667A KR20047002667A KR100920599B1 KR 100920599 B1 KR100920599 B1 KR 100920599B1 KR 1020047002667 A KR1020047002667 A KR 1020047002667A KR 20047002667 A KR20047002667 A KR 20047002667A KR 100920599 B1 KR100920599 B1 KR 100920599B1
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KR
South Korea
Prior art keywords
methacrylate
acrylate
monomer mixture
active compound
functional groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020047002667A
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English (en)
Korean (ko)
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KR20040044477A (ko
Inventor
토마스 힐레
프랭크 테오발트
로베르트-페터 클라인
Original Assignee
에르테에스 로만 테라피-시스테메 아게
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7696570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100920599(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 에르테에스 로만 테라피-시스테메 아게 filed Critical 에르테에스 로만 테라피-시스테메 아게
Publication of KR20040044477A publication Critical patent/KR20040044477A/ko
Application granted granted Critical
Publication of KR100920599B1 publication Critical patent/KR100920599B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
KR1020047002667A 2001-08-24 2002-08-13 작용기를 함유하지 않는 폴리아크릴레이트 접촉 결합 접착제에 기초한 경피 제제 Expired - Fee Related KR100920599B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10141652.0 2001-08-24
DE10141652A DE10141652B4 (de) 2001-08-24 2001-08-24 Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
PCT/EP2002/009057 WO2003017988A1 (de) 2001-08-24 2002-08-13 Transdermales therapeutisches system auf der basis von polyacrylat-haftklebern ohne funktionelle gruppen

Publications (2)

Publication Number Publication Date
KR20040044477A KR20040044477A (ko) 2004-05-28
KR100920599B1 true KR100920599B1 (ko) 2009-10-08

Family

ID=7696570

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047002667A Expired - Fee Related KR100920599B1 (ko) 2001-08-24 2002-08-13 작용기를 함유하지 않는 폴리아크릴레이트 접촉 결합 접착제에 기초한 경피 제제

Country Status (13)

Country Link
US (1) US20040241219A1 (enExample)
EP (1) EP1418895B1 (enExample)
JP (1) JP4393188B2 (enExample)
KR (1) KR100920599B1 (enExample)
CN (1) CN1239153C (enExample)
AU (1) AU2002327831B2 (enExample)
BR (1) BRPI0211993B8 (enExample)
CA (1) CA2455064C (enExample)
DE (1) DE10141652B4 (enExample)
ES (1) ES2397920T3 (enExample)
MX (1) MXPA04001677A (enExample)
WO (1) WO2003017988A1 (enExample)
ZA (1) ZA200400312B (enExample)

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MXPA06000852A (es) * 2003-07-24 2006-03-30 Smithkline Beecham Corp Peliculas que se disuelven oralmente.
WO2005099766A1 (ja) * 2004-04-13 2005-10-27 Saitama Daiichi Pharmaceutical Co., Ltd. 架橋型皮膚用粘着剤
CN1329022C (zh) * 2004-08-31 2007-08-01 贵州太和制药有限公司 亲水性生物粘附凝胶贴剂及其制备工艺
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CN1320008C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羧基基团的丙烯酸酯的组合物
CN1320006C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带酯基基团的丙烯酸酯的组合物
CN1326894C (zh) * 2005-03-24 2007-07-18 上海交通大学 包含酯基部分带烷氧基的丙烯酸酯的组合物
CN1320009C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羟基基团的丙烯酸酯的组合物
DE102006050558B4 (de) 2006-10-26 2009-03-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution
KR100956023B1 (ko) * 2007-09-28 2010-05-06 대화제약 주식회사 산성 관능기를 갖는 아크릴레이트계 고분자의 함량으로약물 방출속도를 제어하는 툴로부테롤 경피 투여용 패취제
DE102008013701A1 (de) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
US20100087768A1 (en) * 2008-10-02 2010-04-08 Forlano Paula Transdermal drug delivery system for liquid active ingredient
US10076502B2 (en) 2009-12-22 2018-09-18 Luye Pharma Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US8962014B2 (en) 2009-12-22 2015-02-24 Acino Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
CN101967213A (zh) * 2010-09-29 2011-02-09 北京化工大学 低分子量带有羧基的聚丙烯酸酯丙烯酸酯的制备方法
ES2545094T3 (es) 2010-12-14 2015-09-08 Acino Ag Sistema terapéutico transdérmico para la administración de un principio activo
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US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
JP6912876B2 (ja) * 2016-10-06 2021-08-04 三洋化成工業株式会社 アクリル系医薬固形製剤用添加剤
DE102017115701B4 (de) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridin-TTS
WO2019068288A1 (de) 2017-10-04 2019-04-11 Berlimed International Research Gmbh Wirkstoff und wirkstoffmatrix enthaltendes produkt zur transdermalen wirkstoffabgabe sowie dessen herstellung und verwendung sowie die wirkstoffmatrix, ihre herstellung und verwendung
DE102018130469A1 (de) 2018-11-30 2020-06-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Diffusionsbarriere
DE102019120403A1 (de) 2019-07-29 2021-02-04 Lts Lohmann Therapie-Systeme Ag Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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Also Published As

Publication number Publication date
CN1545408A (zh) 2004-11-10
WO2003017988A1 (de) 2003-03-06
CN1239153C (zh) 2006-02-01
ES2397920T3 (es) 2013-03-12
MXPA04001677A (es) 2004-05-31
US20040241219A1 (en) 2004-12-02
EP1418895A1 (de) 2004-05-19
AU2002327831B2 (en) 2007-10-25
ZA200400312B (en) 2004-11-01
JP4393188B2 (ja) 2010-01-06
DE10141652B4 (de) 2011-04-07
HK1069533A1 (en) 2005-05-27
BRPI0211993B1 (pt) 2017-04-11
EP1418895B1 (de) 2012-12-19
CA2455064C (en) 2010-08-03
KR20040044477A (ko) 2004-05-28
BR0211993A (pt) 2004-09-28
BRPI0211993B8 (pt) 2021-07-27
DE10141652A1 (de) 2003-03-13
CA2455064A1 (en) 2003-03-06
JP2005503390A (ja) 2005-02-03

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