BRPI0211993B8 - sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais - Google Patents
sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionaisInfo
- Publication number
- BRPI0211993B8 BRPI0211993B8 BRPI0211993A BR0211993A BRPI0211993B8 BR PI0211993 B8 BRPI0211993 B8 BR PI0211993B8 BR PI0211993 A BRPI0211993 A BR PI0211993A BR 0211993 A BR0211993 A BR 0211993A BR PI0211993 B8 BRPI0211993 B8 BR PI0211993B8
- Authority
- BR
- Brazil
- Prior art keywords
- functional groups
- therapeutic system
- transdermal therapeutic
- system based
- polyacrylate
- Prior art date
Links
- 229920000058 polyacrylate Polymers 0.000 title abstract 4
- 125000000524 functional group Chemical group 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 239000000853 adhesive Substances 0.000 title abstract 2
- 230000001070 adhesive effect Effects 0.000 title abstract 2
- 239000010410 layer Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10141652A DE10141652B4 (de) | 2001-08-24 | 2001-08-24 | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| PCT/EP2002/009057 WO2003017988A1 (de) | 2001-08-24 | 2002-08-13 | Transdermales therapeutisches system auf der basis von polyacrylat-haftklebern ohne funktionelle gruppen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0211993A BR0211993A (pt) | 2004-09-28 |
| BRPI0211993B1 BRPI0211993B1 (pt) | 2017-04-11 |
| BRPI0211993B8 true BRPI0211993B8 (pt) | 2021-07-27 |
Family
ID=7696570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0211993A BRPI0211993B8 (pt) | 2001-08-24 | 2002-08-13 | sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20040241219A1 (enExample) |
| EP (1) | EP1418895B1 (enExample) |
| JP (1) | JP4393188B2 (enExample) |
| KR (1) | KR100920599B1 (enExample) |
| CN (1) | CN1239153C (enExample) |
| AU (1) | AU2002327831B2 (enExample) |
| BR (1) | BRPI0211993B8 (enExample) |
| CA (1) | CA2455064C (enExample) |
| DE (1) | DE10141652B4 (enExample) |
| ES (1) | ES2397920T3 (enExample) |
| MX (1) | MXPA04001677A (enExample) |
| WO (1) | WO2003017988A1 (enExample) |
| ZA (1) | ZA200400312B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9056060B2 (en) | 2000-09-19 | 2015-06-16 | Henkel Ag & Co. Kgaa | Non-reactive adhesive useful in transdermal drug delivery system |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| TW200514579A (en) * | 2003-07-24 | 2005-05-01 | Smithkline Beecham Corp | Orally dissolving films |
| US20070196455A1 (en) * | 2004-04-13 | 2007-08-23 | Saitama Daiichi Pharmaceutical Co., Ltd. | Crosslinkable pressure-sensitive adhesive for skin |
| CN1329022C (zh) * | 2004-08-31 | 2007-08-01 | 贵州太和制药有限公司 | 亲水性生物粘附凝胶贴剂及其制备工艺 |
| RU2385719C2 (ru) * | 2005-03-12 | 2010-04-10 | Унилевер Нв | Композиции для ухода за волосами и/или кожей головы, включающие виснадин |
| CN1320006C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带酯基基团的丙烯酸酯的组合物 |
| CN1320005C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带烷烃基的丙烯酸酯的组合物 |
| CN1320008C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带羧基基团的丙烯酸酯的组合物 |
| CN1326894C (zh) * | 2005-03-24 | 2007-07-18 | 上海交通大学 | 包含酯基部分带烷氧基的丙烯酸酯的组合物 |
| CN1320009C (zh) * | 2005-03-24 | 2007-06-06 | 上海交通大学 | 包含酯基部分带羟基基团的丙烯酸酯的组合物 |
| DE102006050558B4 (de) | 2006-10-26 | 2009-03-26 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution |
| KR100956023B1 (ko) * | 2007-09-28 | 2010-05-06 | 대화제약 주식회사 | 산성 관능기를 갖는 아크릴레이트계 고분자의 함량으로약물 방출속도를 제어하는 툴로부테롤 경피 투여용 패취제 |
| DE102008013701A1 (de) * | 2008-03-11 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit stabilisierter Membran |
| US20100087768A1 (en) * | 2008-10-02 | 2010-04-08 | Forlano Paula | Transdermal drug delivery system for liquid active ingredient |
| US10076502B2 (en) | 2009-12-22 | 2018-09-18 | Luye Pharma Ag | Transdermal therapeutic system for administering rivastigmine or derivatives thereof |
| MX350357B (es) * | 2009-12-22 | 2017-09-05 | Luye Pharma Ag | Sistema terapeutico transdermico para administrar rivastigmina o derivados de este. |
| CN101967213A (zh) * | 2010-09-29 | 2011-02-09 | 北京化工大学 | 低分子量带有羧基的聚丙烯酸酯丙烯酸酯的制备方法 |
| EP2468274B1 (de) | 2010-12-14 | 2015-07-01 | Acino AG | Transdermales therapeutisches System zur Verabreichung eines Wirkstoffs |
| CA2856520C (en) | 2011-11-23 | 2021-04-06 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| AR100562A1 (es) | 2014-05-22 | 2016-10-12 | Therapeuticsmd Inc | Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| AU2017239645A1 (en) | 2016-04-01 | 2018-10-18 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| JP6912876B2 (ja) * | 2016-10-06 | 2021-08-04 | 三洋化成工業株式会社 | アクリル系医薬固形製剤用添加剤 |
| DE102017115701B4 (de) * | 2017-07-12 | 2022-03-03 | Lts Lohmann Therapie-Systeme Ag | Fampridin-TTS |
| WO2019068288A1 (de) | 2017-10-04 | 2019-04-11 | Berlimed International Research Gmbh | Wirkstoff und wirkstoffmatrix enthaltendes produkt zur transdermalen wirkstoffabgabe sowie dessen herstellung und verwendung sowie die wirkstoffmatrix, ihre herstellung und verwendung |
| DE102018130469A1 (de) | 2018-11-30 | 2020-06-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit Diffusionsbarriere |
| DE102019120403A1 (de) | 2019-07-29 | 2021-02-04 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2693212B2 (ja) * | 1989-03-28 | 1997-12-24 | 日東電工株式会社 | 疾患治療用テープ製剤 |
| AU644815B2 (en) * | 1989-09-08 | 1993-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Solid matrix system for transdermal drug delivery |
| DE3933460A1 (de) * | 1989-10-06 | 1991-04-18 | Lohmann Therapie Syst Lts | Oestrogenhaltiges wirkstoffpflaster |
| CA2039586A1 (en) * | 1990-05-02 | 1991-11-03 | Marian R. Appelt | Crosslinked pressure-sensitive adhesives tolerant of alcohol-based excipients used in transdermal delivery devices and method of preparing same |
| IT1253265B (it) * | 1991-11-25 | 1995-07-14 | Rotta Research Lab | Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo. |
| WO1993010722A2 (en) * | 1991-11-26 | 1993-06-10 | Research Development Foundation | Fetal membrane tubes for nerve and vessel grafts |
| DE4301783C1 (de) * | 1993-01-23 | 1994-02-03 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Galanthamin als wirksamem Bestandteil |
| DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
| EP0813865B1 (de) * | 1993-04-20 | 2001-09-19 | Hexal Ag | Wirkstoffpflaster |
| JPH09503997A (ja) * | 1993-07-08 | 1997-04-22 | シグナス,インコーポレイテッド | モノリシックなマトリックス経皮送達システム |
| US5554381A (en) * | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
| ES2122140T3 (es) * | 1993-12-30 | 1998-12-16 | Rotta Res Bv | Parche transdermico con dinitrato de isosorbida como ingrediente activo. |
| DE4403487C2 (de) * | 1994-02-04 | 2003-10-16 | Lohmann Therapie Syst Lts | Arznei-Pflaster mit UV-vernetzbaren Acrylat-Copolymeren |
| US5614210A (en) * | 1995-03-31 | 1997-03-25 | Minnesota Mining And Manufacturing Company | Transdermal device for the delivery of alfuzosin |
| SE504430C2 (sv) | 1995-06-20 | 1997-02-10 | Ericsson Telefon Ab L M | Magasin |
| JPH1036265A (ja) * | 1996-07-19 | 1998-02-10 | Nitto Denko Corp | ブプレノルフィン経皮吸収製剤 |
| US5928666A (en) * | 1996-11-12 | 1999-07-27 | Cygnus Inc. | Crystalline form of estradiol and pharmaceutical formulations comprising same |
| US6210705B1 (en) * | 1997-12-15 | 2001-04-03 | Noven Pharmaceuticals, Nc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE19830651A1 (de) * | 1998-07-09 | 2000-01-13 | Lohmann Therapie Syst Lts | Steroidhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung |
| WO2000041538A2 (en) * | 1999-01-14 | 2000-07-20 | Noven Pharmaceuticals, Inc. | Dermal compositions |
| ATE287711T1 (de) | 1999-11-29 | 2005-02-15 | Novosis Ag | Transdermalsystem zur abgabe von clonidin |
| DE10032537A1 (de) * | 2000-07-05 | 2002-01-31 | Labtec Gmbh | Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure |
| US9056060B2 (en) * | 2000-09-19 | 2015-06-16 | Henkel Ag & Co. Kgaa | Non-reactive adhesive useful in transdermal drug delivery system |
-
2001
- 2001-08-24 DE DE10141652A patent/DE10141652B4/de not_active Expired - Lifetime
-
2002
- 2002-08-13 CN CNB028164385A patent/CN1239153C/zh not_active Expired - Fee Related
- 2002-08-13 KR KR1020047002667A patent/KR100920599B1/ko not_active Expired - Fee Related
- 2002-08-13 CA CA2455064A patent/CA2455064C/en not_active Expired - Lifetime
- 2002-08-13 MX MXPA04001677A patent/MXPA04001677A/es active IP Right Grant
- 2002-08-13 AU AU2002327831A patent/AU2002327831B2/en not_active Ceased
- 2002-08-13 JP JP2003522508A patent/JP4393188B2/ja not_active Expired - Fee Related
- 2002-08-13 EP EP02762444A patent/EP1418895B1/de not_active Revoked
- 2002-08-13 BR BRPI0211993A patent/BRPI0211993B8/pt not_active IP Right Cessation
- 2002-08-13 WO PCT/EP2002/009057 patent/WO2003017988A1/de not_active Ceased
- 2002-08-13 US US10/487,380 patent/US20040241219A1/en not_active Abandoned
- 2002-08-13 ES ES02762444T patent/ES2397920T3/es not_active Expired - Lifetime
-
2004
- 2004-01-15 ZA ZA200400312A patent/ZA200400312B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003017988A1 (de) | 2003-03-06 |
| BR0211993A (pt) | 2004-09-28 |
| EP1418895B1 (de) | 2012-12-19 |
| CA2455064A1 (en) | 2003-03-06 |
| CN1239153C (zh) | 2006-02-01 |
| MXPA04001677A (es) | 2004-05-31 |
| DE10141652B4 (de) | 2011-04-07 |
| ES2397920T3 (es) | 2013-03-12 |
| JP4393188B2 (ja) | 2010-01-06 |
| BRPI0211993B1 (pt) | 2017-04-11 |
| US20040241219A1 (en) | 2004-12-02 |
| JP2005503390A (ja) | 2005-02-03 |
| ZA200400312B (en) | 2004-11-01 |
| DE10141652A1 (de) | 2003-03-13 |
| CA2455064C (en) | 2010-08-03 |
| EP1418895A1 (de) | 2004-05-19 |
| KR20040044477A (ko) | 2004-05-28 |
| KR100920599B1 (ko) | 2009-10-08 |
| AU2002327831B2 (en) | 2007-10-25 |
| HK1069533A1 (en) | 2005-05-27 |
| CN1545408A (zh) | 2004-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07B | Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM OS ARTIGOS 8O, 11 E 13 DA LPI. |
|
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