BRPI0211993B8 - sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais - Google Patents

sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais

Info

Publication number
BRPI0211993B8
BRPI0211993B8 BRPI0211993A BR0211993A BRPI0211993B8 BR PI0211993 B8 BRPI0211993 B8 BR PI0211993B8 BR PI0211993 A BRPI0211993 A BR PI0211993A BR 0211993 A BR0211993 A BR 0211993A BR PI0211993 B8 BRPI0211993 B8 BR PI0211993B8
Authority
BR
Brazil
Prior art keywords
functional groups
therapeutic system
transdermal therapeutic
system based
polyacrylate
Prior art date
Application number
BRPI0211993A
Other languages
English (en)
Other versions
BRPI0211993B1 (pt
BR0211993A (pt
Inventor
Theobald Frank
Klein Robert-Peter
Hille Thomas
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7696570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0211993(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of BR0211993A publication Critical patent/BR0211993A/pt
Publication of BRPI0211993B1 publication Critical patent/BRPI0211993B1/pt
Publication of BRPI0211993B8 publication Critical patent/BRPI0211993B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

"sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais". a presente invenção descreve um sistema terapêutico transdermal (tts) com camada posterior, camada de proteção e camada polímera contendo substância ativa, sendo que a matriz polímera contém um poliacrilato contendo uma fração extremamente reduzida de grupos funcionais. em uma forma particular de execução, o poliacrilato é isento de grupos hidroxila e/ou grupos carboxila.
BRPI0211993A 2001-08-24 2002-08-13 sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais BRPI0211993B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10141652A DE10141652B4 (de) 2001-08-24 2001-08-24 Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
PCT/EP2002/009057 WO2003017988A1 (de) 2001-08-24 2002-08-13 Transdermales therapeutisches system auf der basis von polyacrylat-haftklebern ohne funktionelle gruppen

Publications (3)

Publication Number Publication Date
BR0211993A BR0211993A (pt) 2004-09-28
BRPI0211993B1 BRPI0211993B1 (pt) 2017-04-11
BRPI0211993B8 true BRPI0211993B8 (pt) 2021-07-27

Family

ID=7696570

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0211993A BRPI0211993B8 (pt) 2001-08-24 2002-08-13 sistema terapêutico transdermal à base de adesivos de poliacrilato sem grupos funcionais

Country Status (14)

Country Link
US (1) US20040241219A1 (pt)
EP (1) EP1418895B1 (pt)
JP (1) JP4393188B2 (pt)
KR (1) KR100920599B1 (pt)
CN (1) CN1239153C (pt)
AU (1) AU2002327831B2 (pt)
BR (1) BRPI0211993B8 (pt)
CA (1) CA2455064C (pt)
DE (1) DE10141652B4 (pt)
ES (1) ES2397920T3 (pt)
HK (1) HK1069533A1 (pt)
MX (1) MXPA04001677A (pt)
WO (1) WO2003017988A1 (pt)
ZA (1) ZA200400312B (pt)

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US9056060B2 (en) 2000-09-19 2015-06-16 Henkel Ag & Co. Kgaa Non-reactive adhesive useful in transdermal drug delivery system
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
HUE037508T2 (hu) * 2003-07-24 2018-09-28 Glaxosmithkline Llc Szájban oldódó filmek
CN100591357C (zh) * 2004-04-13 2010-02-24 尼普洛外用药品株式会社 交联型皮肤用胶粘剂
CN1329022C (zh) * 2004-08-31 2007-08-01 贵州太和制药有限公司 亲水性生物粘附凝胶贴剂及其制备工艺
EP1915198B1 (en) * 2005-03-12 2011-04-06 Unilever PLC Visnadin for treating scalp skin itching
CN1320008C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羧基基团的丙烯酸酯的组合物
CN1320006C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带酯基基团的丙烯酸酯的组合物
CN1326894C (zh) * 2005-03-24 2007-07-18 上海交通大学 包含酯基部分带烷氧基的丙烯酸酯的组合物
CN1320009C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带羟基基团的丙烯酸酯的组合物
CN1320005C (zh) * 2005-03-24 2007-06-06 上海交通大学 包含酯基部分带烷烃基的丙烯酸酯的组合物
DE102006050558B4 (de) 2006-10-26 2009-03-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution
KR100956023B1 (ko) * 2007-09-28 2010-05-06 대화제약 주식회사 산성 관능기를 갖는 아크릴레이트계 고분자의 함량으로약물 방출속도를 제어하는 툴로부테롤 경피 투여용 패취제
DE102008013701A1 (de) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
US20100087768A1 (en) * 2008-10-02 2010-04-08 Forlano Paula Transdermal drug delivery system for liquid active ingredient
WO2011076621A2 (de) 2009-12-22 2011-06-30 Acino Ag Transdermales therapeutisches system zur verabreichung von rivastigmin oder dessen derivaten
US10076502B2 (en) 2009-12-22 2018-09-18 Luye Pharma Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
CN101967213A (zh) * 2010-09-29 2011-02-09 北京化工大学 低分子量带有羧基的聚丙烯酸酯丙烯酸酯的制备方法
RS54173B1 (en) 2010-12-14 2015-12-31 Acino Ag TRANSDERMAL THERAPY SYSTEM FOR ACTIVE SUBSTANCE
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CA2856520C (en) 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
JP6912876B2 (ja) * 2016-10-06 2021-08-04 三洋化成工業株式会社 アクリル系医薬固形製剤用添加剤
DE102017115701B4 (de) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridin-TTS
WO2019068288A1 (de) 2017-10-04 2019-04-11 Berlimed International Research Gmbh Wirkstoff und wirkstoffmatrix enthaltendes produkt zur transdermalen wirkstoffabgabe sowie dessen herstellung und verwendung sowie die wirkstoffmatrix, ihre herstellung und verwendung
DE102018130469A1 (de) 2018-11-30 2020-06-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Diffusionsbarriere
DE102019120403A1 (de) 2019-07-29 2021-02-04 Lts Lohmann Therapie-Systeme Ag Verfahren zur Herstellung von Haftklebemassen zur Verwendung in einem transdermalen therapeutischen System
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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Also Published As

Publication number Publication date
JP4393188B2 (ja) 2010-01-06
KR100920599B1 (ko) 2009-10-08
BRPI0211993B1 (pt) 2017-04-11
CA2455064A1 (en) 2003-03-06
WO2003017988A1 (de) 2003-03-06
JP2005503390A (ja) 2005-02-03
ZA200400312B (en) 2004-11-01
DE10141652B4 (de) 2011-04-07
MXPA04001677A (es) 2004-05-31
EP1418895A1 (de) 2004-05-19
AU2002327831B2 (en) 2007-10-25
HK1069533A1 (en) 2005-05-27
CN1239153C (zh) 2006-02-01
KR20040044477A (ko) 2004-05-28
ES2397920T3 (es) 2013-03-12
US20040241219A1 (en) 2004-12-02
BR0211993A (pt) 2004-09-28
CA2455064C (en) 2010-08-03
EP1418895B1 (de) 2012-12-19
CN1545408A (zh) 2004-11-10
DE10141652A1 (de) 2003-03-13

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