KR100808324B1 - 아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ 효능제로서의 용도 - Google Patents

아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ 효능제로서의 용도 Download PDF

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KR100808324B1
KR100808324B1 KR20057003665A KR20057003665A KR100808324B1 KR 100808324 B1 KR100808324 B1 KR 100808324B1 KR 20057003665 A KR20057003665 A KR 20057003665A KR 20057003665 A KR20057003665 A KR 20057003665A KR 100808324 B1 KR100808324 B1 KR 100808324B1
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substituted
halogen
aza
unsubstituted
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KR20050057126A (ko
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도미니크 페우어바흐
콘스탄쯔 후르쓰
티모시 존 리치
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노파르티스 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P25/34—Tobacco-abuse
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

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  • Rheumatology (AREA)
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  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR20057003665A 2002-09-04 2003-09-03 아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ 효능제로서의 용도 Expired - Lifetime KR100808324B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0220581A GB0220581D0 (en) 2002-09-04 2002-09-04 Organic Compound
GB0220581.3 2002-09-04

Related Child Applications (1)

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KR1020077011698A Division KR20070058027A (ko) 2002-09-04 2003-09-03 아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ효능제로서의 용도

Publications (2)

Publication Number Publication Date
KR20050057126A KR20050057126A (ko) 2005-06-16
KR100808324B1 true KR100808324B1 (ko) 2008-02-27

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KR20057003665A Expired - Lifetime KR100808324B1 (ko) 2002-09-04 2003-09-03 아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ 효능제로서의 용도
KR1020077011698A Ceased KR20070058027A (ko) 2002-09-04 2003-09-03 아자-비시클로알킬 에테르 및 이들의 알파７-ｎＡＣｈＲ효능제로서의 용도

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US (8) US20060167002A1 (enExample)
EP (3) EP1537104B1 (enExample)
JP (2) JP4348422B2 (enExample)
KR (2) KR100808324B1 (enExample)
CN (1) CN1325493C (enExample)
AT (1) ATE448225T1 (enExample)
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BR (2) BR122014026685B1 (enExample)
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CY (1) CY1109765T1 (enExample)
DE (1) DE60330015D1 (enExample)
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GB (1) GB0220581D0 (enExample)
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NZ (1) NZ538534A (enExample)
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PT (1) PT1537104E (enExample)
RU (1) RU2352569C2 (enExample)
SI (1) SI1537104T1 (enExample)
WO (1) WO2004022556A1 (enExample)
ZA (1) ZA200500816B (enExample)

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