KR100699390B1 - 9-치환된 미노사이클린 화합물 - Google Patents

9-치환된 미노사이클린 화합물 Download PDF

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KR100699390B1
KR100699390B1 KR1020057025319A KR20057025319A KR100699390B1 KR 100699390 B1 KR100699390 B1 KR 100699390B1 KR 1020057025319 A KR1020057025319 A KR 1020057025319A KR 20057025319 A KR20057025319 A KR 20057025319A KR 100699390 B1 KR100699390 B1 KR 100699390B1
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minocycline
group
substituted
alkyl
compound according
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KR20060014446A (ko
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마크 엘. 넬슨
로저 프레체트
피터 비스키
모하메드 이스마일
토드 보우저
지미 더모네이
글렌 레니
구이 리우
다렐 코자
폴 쉬한
카렌 스테이플톤
폴 호킨스
비나 바티아
아툴 베르마
로라 맥킨타이어
태드 와콜
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트러스티즈 오브 터프츠 칼리지
파라테크 파마슈티컬스, 인크.
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
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    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
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    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
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    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
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    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020057025319A 2000-07-07 2001-06-29 9-치환된 미노사이클린 화합물 Expired - Fee Related KR100699390B1 (ko)

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Application Number Priority Date Filing Date Title
US21665900P 2000-07-07 2000-07-07
US60/216,659 2000-07-07
US27562101P 2001-03-13 2001-03-13
US60/275,621 2001-03-13

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