KR100564130B1 - 약학적 약물 전달계를 위한 생체적합성 화합물 - Google Patents

약학적 약물 전달계를 위한 생체적합성 화합물 Download PDF

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Publication number
KR100564130B1
KR100564130B1 KR1019997007128A KR19997007128A KR100564130B1 KR 100564130 B1 KR100564130 B1 KR 100564130B1 KR 1019997007128 A KR1019997007128 A KR 1019997007128A KR 19997007128 A KR19997007128 A KR 19997007128A KR 100564130 B1 KR100564130 B1 KR 100564130B1
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KR
South Korea
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drug
polymer
acid
molecular weight
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Expired - Fee Related
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KR1019997007128A
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English (en)
Korean (ko)
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KR20000070863A (ko
Inventor
스티플리제임스에스
슐츠데이비드더블유
샬링어류크이
퍼맨크레이그에이
리치체스터엘
듀언대니얼씨.
Original Assignee
미네소타 마이닝 앤드 매뉴팩춰링 캄파니
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Publication of KR20000070863A publication Critical patent/KR20000070863A/ko
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Publication of KR100564130B1 publication Critical patent/KR100564130B1/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
KR1019997007128A 1997-02-07 1998-02-04 약학적 약물 전달계를 위한 생체적합성 화합물 Expired - Fee Related KR100564130B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8/797,803 1997-02-07
US08/797,803 1997-02-07
US08/797,803 US6126919A (en) 1997-02-07 1997-02-07 Biocompatible compounds for pharmaceutical drug delivery systems
PCT/US1998/000074 WO1998034596A2 (en) 1997-02-07 1998-02-04 Biocompatible compounds for pharmaceutical drug delivery systems

Publications (2)

Publication Number Publication Date
KR20000070863A KR20000070863A (ko) 2000-11-25
KR100564130B1 true KR100564130B1 (ko) 2006-03-27

Family

ID=25171845

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019997007128A Expired - Fee Related KR100564130B1 (ko) 1997-02-07 1998-02-04 약학적 약물 전달계를 위한 생체적합성 화합물

Country Status (14)

Country Link
US (3) US6126919A (enExample)
EP (2) EP1014944B1 (enExample)
JP (1) JP2001511179A (enExample)
KR (1) KR100564130B1 (enExample)
CN (1) CN1114400C (enExample)
AT (1) ATE359062T1 (enExample)
AU (1) AU724765B2 (enExample)
CA (1) CA2279522C (enExample)
DE (1) DE69837549T2 (enExample)
HU (1) HUP0001914A3 (enExample)
IL (1) IL130993A0 (enExample)
NZ (1) NZ336903A (enExample)
PL (1) PL196261B1 (enExample)
WO (1) WO1998034596A2 (enExample)

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