SE9804001D0 - New process - Google Patents
New processInfo
- Publication number
- SE9804001D0 SE9804001D0 SE9804001A SE9804001A SE9804001D0 SE 9804001 D0 SE9804001 D0 SE 9804001D0 SE 9804001 A SE9804001 A SE 9804001A SE 9804001 A SE9804001 A SE 9804001A SE 9804001 D0 SE9804001 D0 SE 9804001D0
- Authority
- SE
- Sweden
- Prior art keywords
- solvent
- substance
- treatment
- water
- formulations
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804001A SE9804001D0 (sv) | 1998-11-23 | 1998-11-23 | New process |
ES99963730T ES2228149T5 (es) | 1998-11-23 | 1999-11-22 | Un procedimiento para la preparacion de particulas cristalinas. |
EP99963730A EP1133284B2 (en) | 1998-11-23 | 1999-11-22 | A process for the preparation of crystalline particles |
JP2000583497A JP4616993B2 (ja) | 1998-11-23 | 1999-11-22 | 新しい製造方法 |
DE69920946T DE69920946T3 (de) | 1998-11-23 | 1999-11-22 | Verfahren zur herstellung kristalliner partikel |
PCT/SE1999/002153 WO2000030613A1 (en) | 1998-11-23 | 1999-11-22 | New process |
PT99963730T PT1133284E (pt) | 1998-11-23 | 1999-11-22 | Um processo para a preparacao de particulas cristalinas |
DK99963730T DK1133284T4 (da) | 1998-11-23 | 1999-11-22 | Fremgangsmåde til fremstilling af krystallinske partikler |
AU20103/00A AU767767B2 (en) | 1998-11-23 | 1999-11-22 | New process |
AT99963730T ATE278391T1 (de) | 1998-11-23 | 1999-11-22 | Verfahren zur herstellung kristalliner partikel |
CA002348084A CA2348084C (en) | 1998-11-23 | 1999-11-22 | Crystallisation using supercritical or subcritical fluids |
US09/486,689 US6461642B1 (en) | 1998-11-23 | 1999-11-22 | Crystallization using supercritical or subcritical fluids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804001A SE9804001D0 (sv) | 1998-11-23 | 1998-11-23 | New process |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9804001D0 true SE9804001D0 (sv) | 1998-11-23 |
Family
ID=20413378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9804001A SE9804001D0 (sv) | 1998-11-23 | 1998-11-23 | New process |
Country Status (12)
Country | Link |
---|---|
US (1) | US6461642B1 (sv) |
EP (1) | EP1133284B2 (sv) |
JP (1) | JP4616993B2 (sv) |
AT (1) | ATE278391T1 (sv) |
AU (1) | AU767767B2 (sv) |
CA (1) | CA2348084C (sv) |
DE (1) | DE69920946T3 (sv) |
DK (1) | DK1133284T4 (sv) |
ES (1) | ES2228149T5 (sv) |
PT (1) | PT1133284E (sv) |
SE (1) | SE9804001D0 (sv) |
WO (1) | WO2000030613A1 (sv) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH694686A5 (it) | 2000-03-04 | 2005-06-15 | Eco2 Sa | Prodotto di micronizzazione di sostanze farmaceutiche. |
GB0016040D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
ES2170008B1 (es) * | 2000-08-25 | 2003-05-01 | Soc Es Carburos Metalicos Sa | Procedimiento para la precipitacion de particulas solidas finamente divididas. |
FR2815540B1 (fr) * | 2000-10-19 | 2005-06-10 | Separex Sa | Procede de fabrication de tres fines particules constituees d'un principe insere dans une molecule hote |
GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
GB0102075D0 (en) * | 2001-01-26 | 2001-03-14 | Astrazeneca Ab | Process |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
IL160570A0 (en) | 2001-09-26 | 2004-07-25 | Baxter Int | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
JP2005511521A (ja) * | 2001-10-10 | 2005-04-28 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 加圧ガス状流体による粉末処理 |
FR2830760B1 (fr) * | 2001-10-12 | 2004-06-04 | Pf Medicament | Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique |
CN1726010A (zh) * | 2002-12-19 | 2006-01-25 | 巴克斯特国际公司 | 使用超临界流体制备组合药物制剂的方法 |
EP1624862B1 (en) | 2003-05-08 | 2014-12-31 | Nektar Therapeutics | Particulate materials |
JP2007501194A (ja) * | 2003-08-05 | 2007-01-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ステロイドとβ模倣薬を含む吸入用薬剤 |
EP1701775B2 (en) * | 2003-11-19 | 2012-06-13 | NATEX Prozesstechnologie GesmbH | A method and process for controlling the temperature, pressure and density profiles in dense fluid processes and associated apparatus |
EP1904219A4 (en) | 2005-07-15 | 2011-07-27 | Map Pharmaceuticals Inc | METHOD FOR FORMING PARTICLES |
EP1782839A1 (en) | 2005-11-03 | 2007-05-09 | Genetic S.p.A. | Sterilization process of Glucocorticosteroid by supercritical CO2 |
EP2049086A2 (en) * | 2006-08-09 | 2009-04-22 | Glaxo Group Limited | Process for manufacturing lactose |
EP2425819A1 (en) | 2007-02-11 | 2012-03-07 | MAP Pharmaceuticals Inc | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
WO2009047935A1 (ja) * | 2007-10-12 | 2009-04-16 | Ono Pharmaceutical Co., Ltd. | 微粒子 |
JP5307382B2 (ja) * | 2007-11-14 | 2013-10-02 | 日機装株式会社 | 微粒子化方法 |
CN101918123B (zh) | 2007-12-07 | 2013-12-18 | X喷雾微粒公司 | 生产微粒的方法与装置 |
DE102008053618A1 (de) * | 2008-10-29 | 2010-07-01 | Karlsruher Institut für Technologie | Verfahren zur Ausfällung von Salzen |
ES2342140B1 (es) | 2008-12-30 | 2011-05-17 | Consejo Superior Investigacion | Procedimiento para la obtencion de micro- o nanoparticulas solidas |
US20100298602A1 (en) * | 2009-05-19 | 2010-11-25 | Massachusetts Institute Of Technology | Systems and methods for microfluidic crystallization |
US20100294986A1 (en) * | 2009-05-19 | 2010-11-25 | Massachusetts Institute Of Technology | Supercritical fluid facilitated particle formation in microfluidic systems |
US9808030B2 (en) | 2011-02-11 | 2017-11-07 | Grain Processing Corporation | Salt composition |
CN102327186A (zh) * | 2011-09-30 | 2012-01-25 | 四川大学 | 一种采用超临界co2流体技术制备水溶性药物缓释微粒的方法 |
GB201402556D0 (en) | 2014-02-13 | 2014-04-02 | Crystec Ltd | Improvements relating to inhalable particles |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3744329A1 (de) * | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
SE9302777D0 (sv) | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
US6063910A (en) † | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
US5301664A (en) * | 1992-03-06 | 1994-04-12 | Sievers Robert E | Methods and apparatus for drug delivery using supercritical solutions |
WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
GB9413202D0 (en) | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
GB9703673D0 (en) | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
AU741783B2 (en) | 1997-03-20 | 2001-12-06 | Merck Sharp & Dohme Corp. | Preparation of powder agglomerates |
-
1998
- 1998-11-23 SE SE9804001A patent/SE9804001D0/sv unknown
-
1999
- 1999-11-22 PT PT99963730T patent/PT1133284E/pt unknown
- 1999-11-22 JP JP2000583497A patent/JP4616993B2/ja not_active Expired - Fee Related
- 1999-11-22 AT AT99963730T patent/ATE278391T1/de active
- 1999-11-22 ES ES99963730T patent/ES2228149T5/es not_active Expired - Lifetime
- 1999-11-22 WO PCT/SE1999/002153 patent/WO2000030613A1/en active IP Right Grant
- 1999-11-22 DK DK99963730T patent/DK1133284T4/da active
- 1999-11-22 DE DE69920946T patent/DE69920946T3/de not_active Expired - Lifetime
- 1999-11-22 AU AU20103/00A patent/AU767767B2/en not_active Ceased
- 1999-11-22 CA CA002348084A patent/CA2348084C/en not_active Expired - Fee Related
- 1999-11-22 US US09/486,689 patent/US6461642B1/en not_active Expired - Fee Related
- 1999-11-22 EP EP99963730A patent/EP1133284B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE278391T1 (de) | 2004-10-15 |
PT1133284E (pt) | 2005-01-31 |
ES2228149T5 (es) | 2008-12-16 |
AU767767B2 (en) | 2003-11-20 |
EP1133284A1 (en) | 2001-09-19 |
JP2002530318A (ja) | 2002-09-17 |
CA2348084C (en) | 2009-01-06 |
DK1133284T4 (da) | 2008-11-10 |
EP1133284B2 (en) | 2008-08-06 |
EP1133284B1 (en) | 2004-10-06 |
DK1133284T3 (da) | 2005-02-28 |
DE69920946D1 (de) | 2004-11-11 |
WO2000030613A1 (en) | 2000-06-02 |
AU2010300A (en) | 2000-06-13 |
DE69920946T3 (de) | 2009-02-26 |
JP4616993B2 (ja) | 2011-01-19 |
CA2348084A1 (en) | 2000-06-02 |
DE69920946T2 (de) | 2005-08-25 |
US6461642B1 (en) | 2002-10-08 |
ES2228149T3 (es) | 2005-04-01 |
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