DE69731623D1 - Saure Polymilchsäure Polymere - Google Patents

Saure Polymilchsäure Polymere

Info

Publication number
DE69731623D1
DE69731623D1 DE69731623A DE69731623A DE69731623D1 DE 69731623 D1 DE69731623 D1 DE 69731623D1 DE 69731623 A DE69731623 A DE 69731623A DE 69731623 A DE69731623 A DE 69731623A DE 69731623 D1 DE69731623 D1 DE 69731623D1
Authority
DE
Germany
Prior art keywords
polylactic acid
acid polymers
acid units
acidic
acidic polylactic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69731623A
Other languages
English (en)
Other versions
DE69731623T4 (de
DE69731623T2 (de
Inventor
Ciaran Loughman
Mary Russell
Jean-Claude Touraud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Manufacturing Ireland Ltd
Original Assignee
Ipsen Manufacturing Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Manufacturing Ireland Ltd filed Critical Ipsen Manufacturing Ireland Ltd
Application granted granted Critical
Publication of DE69731623D1 publication Critical patent/DE69731623D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/91—Polymers modified by chemical after-treatment
    • C08G63/912—Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/60—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from the reaction of a mixture of hydroxy carboxylic acids, polycarboxylic acids and polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
DE69731623A 1996-04-23 1997-04-22 Saure Polymilchsäure Polymere Expired - Fee Related DE69731623D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IE1997/000031 WO1997040085A2 (en) 1996-04-23 1997-04-22 Acidic polylactic polymers
IE960307A IE960307A1 (en) 1996-04-23 1998-10-07 Acidic polylactic polymers

Publications (1)

Publication Number Publication Date
DE69731623D1 true DE69731623D1 (de) 2004-12-23

Family

ID=11041149

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69731623T Expired - Lifetime DE69731623T4 (de) 1996-04-23 1997-04-22 Saure Polymilchsäure Polymere
DE69731623A Expired - Fee Related DE69731623D1 (de) 1996-04-23 1997-04-22 Saure Polymilchsäure Polymere

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69731623T Expired - Lifetime DE69731623T4 (de) 1996-04-23 1997-04-22 Saure Polymilchsäure Polymere

Country Status (18)

Country Link
US (1) US6111033A (de)
EP (3) EP1479707A3 (de)
JP (2) JP3155013B2 (de)
AT (1) ATE282653T1 (de)
AU (1) AU727340C (de)
CA (1) CA2250981C (de)
CZ (1) CZ299398A3 (de)
DE (2) DE69731623T4 (de)
DK (1) DK0895517T3 (de)
ES (1) ES2234014T3 (de)
HU (1) HUP0000732A3 (de)
IE (1) IE960307A1 (de)
IL (1) IL126422A (de)
NO (1) NO984923L (de)
NZ (1) NZ332018A (de)
PL (1) PL329598A1 (de)
RU (1) RU2165942C2 (de)
WO (1) WO1997040085A2 (de)

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US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
UA54505C2 (uk) 1997-04-03 2003-03-17 Гілфорд Фармасьютікалз Інк. Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання
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US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
WO1999021915A1 (fr) * 1997-10-29 1999-05-06 Kanebo, Limited Composition de resine biodegradable et capable de former de la mousse
EP1096957A1 (de) 1998-06-18 2001-05-09 Johns Hopkins University School of Medicine Verfahren und reagentien zur intramuskulären zufuhr von nukleinsäuren
US6419709B1 (en) 1998-10-02 2002-07-16 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
US6153212A (en) 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
US6350464B1 (en) 1999-01-11 2002-02-26 Guilford Pharmaceuticals, Inc. Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
US6537585B1 (en) 1999-03-26 2003-03-25 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
US7109166B1 (en) 1999-08-18 2006-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Sustained release formulation of a peptide
EP1348444B1 (de) * 1999-08-18 2006-04-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist
NZ526127A (en) * 1999-08-18 2005-02-25 Sod Conseils Rech Applic Use of a somatostatin analog in the manufacture of a medicament
JP4565290B2 (ja) * 1999-12-01 2010-10-20 東洋紡績株式会社 高水酸基濃度を有するオキシ酸系脂肪族ポリエステルおよびオキシ酸系脂肪族ポリエステル組成物
JP3450810B2 (ja) * 2000-01-31 2003-09-29 キヤノン株式会社 脂肪族ポリエステル、脂肪族ポリエステルの製造方法およびセルロースの再資源化方法
FR2821360B1 (fr) * 2001-02-27 2003-05-30 Sod Conseils Rech Applic Procede de preparation de polyesters avec des fonctions acides libres intracatenaires
US20030045798A1 (en) * 2001-09-04 2003-03-06 Richard Hular Multisensor probe for tissue identification
WO2003080629A2 (en) 2002-02-25 2003-10-02 Guilford Pharmaceuticals, Inc. Phosphorus-containing compounds with polymeric chains, and methods of making and using the same
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
BR122018074353B8 (pt) 2003-01-28 2023-05-02 Ironwood Pharmaceuticals Inc composição farmacêutica, polipeptídeo e métodos para a produção dos mesmos
AU2004287875B2 (en) 2003-11-05 2011-06-02 Bausch + Lomb Ireland Limited Modulators of cellular adhesion
KR20050054129A (ko) * 2003-12-04 2005-06-10 주식회사 삼양사 고분자 미셀을 형성하는 생분해성 분지형 폴리락트산유도체, 및 그의 제조방법 및 용도
ATE505503T1 (de) * 2003-12-30 2011-04-15 3M Innovative Properties Co Herstellungsverfahren von medizinischen zusammensetzungen
CA2985444C (en) 2005-05-17 2019-03-12 Sarcode Bioscience Inc. Compositions and methods for treatment of eye disorders
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2830024T3 (es) 2007-10-19 2021-06-02 Novartis Ag Composiciones y métodos para el tratamiento del edema macular
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
AU2009256157B2 (en) 2008-06-04 2014-12-18 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (de) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
WO2011096968A1 (en) * 2010-02-08 2011-08-11 Danimer Scientific, Llc Degradable polymers for hydrocarbon extraction
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2705013B1 (de) 2011-05-04 2016-03-30 Balance Therapeutics, Inc. Pentylentetrazolderivate
JPWO2013042677A1 (ja) * 2011-09-20 2015-03-26 東洋紡株式会社 ポリ乳酸系ポリエステル樹脂、ポリ乳酸系ポリエステル樹脂水分散体、水性接着剤、及びポリ乳酸系ポリエステル樹脂水分散体の製造方法
RU2467029C1 (ru) * 2011-10-25 2012-11-20 Российская Федерация, От Имени Которой Выступает Министерство Промышленности И Торговли Российской Федерации Способ получения биоразлагаемых полиэфиров
US9670311B2 (en) * 2012-02-17 2017-06-06 Toyobo Co., Ltd Polylactic polyester resin, aqueous polylactic polyester resin dispersion, and production method for aqueous polylactic polyester resin dispersion
CN104105758B (zh) * 2012-04-27 2016-07-06 株式会社吴羽 聚酯树脂组合物及其成型体
US10675376B2 (en) * 2012-05-24 2020-06-09 Ethicon Llc Mechanically strong absorbable polymeric blend compositions of precisely controllable absorption rates, processing methods, and products therefrom
BR112015001608B1 (pt) 2012-07-25 2022-08-23 Novartis Ag Métodos para purificação e síntese de um composto inibidor lfa-1, mistura reacional e composições compreendendo o dito composto e composto isolado inibidor lfa-1
KR101548314B1 (ko) * 2012-12-17 2015-08-28 주식회사 엘지화학 폴리락타이드 수지의 제조방법
CA2902348C (en) 2013-02-25 2021-11-30 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
US20140274820A1 (en) * 2013-03-15 2014-09-18 Danimer Scientific, Llc Degradable polymers and method for fracking applications
MY176976A (en) 2013-10-10 2020-08-28 Bausch Health Ireland Ltd Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
WO2017123634A1 (en) 2016-01-11 2017-07-20 Synergy Pharmaceuticals, Inc. Formulations and methods for treating ulcerative colitis
RU2715383C1 (ru) * 2019-06-20 2020-02-27 Общество с ограниченной ответственностью "ТВС" Способ получения (со)полимера гликолида и/или лактида для изготовления рассасывающихся хирургических изделий
CN114940746B (zh) * 2022-06-17 2024-04-26 山东采采医疗科技有限公司 星型丙交酯乙交酯共聚物及作为药物缓释载体的用途

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IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4523591A (en) * 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
DE3936191C2 (de) * 1989-10-31 1996-10-17 Boehringer Ingelheim Kg Neue Copolymere aus Milchsäure und Weinsäure, ihre Herstellung sowie ihre Verwendung
JPH0665230A (ja) * 1992-08-19 1994-03-08 Showa Denko Kk ラクチドの製造方法
US5672659A (en) * 1993-01-06 1997-09-30 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
ES2196023T3 (es) * 1993-01-06 2003-12-16 Kinerton Ltd Conjugados moleculares ionicos de poliesteres biodegradables y polipeptidos bioactivos.
AU706434B2 (en) * 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation

Also Published As

Publication number Publication date
CZ299398A3 (cs) 1999-01-13
DE69731623T4 (de) 2006-08-31
HUP0000732A3 (en) 2000-11-28
CA2250981C (en) 2002-07-02
DE69731623T2 (de) 2005-10-06
DK0895517T3 (da) 2005-01-17
EP0895517B1 (de) 2004-11-17
EP1479707A3 (de) 2005-05-18
EP0895517A2 (de) 1999-02-10
CA2250981A1 (en) 1997-10-30
IL126422A0 (en) 1999-05-09
AU2575297A (en) 1997-11-12
EP1479708A2 (de) 2004-11-24
EP1479708A3 (de) 2005-05-25
JPH11508640A (ja) 1999-07-27
HUP0000732A2 (en) 2000-07-28
WO1997040085A3 (en) 1998-01-22
RU2165942C2 (ru) 2001-04-27
WO1997040085A2 (en) 1997-10-30
AU727340B2 (en) 2000-12-07
JP2001181378A (ja) 2001-07-03
NO984923D0 (no) 1998-10-22
US6111033A (en) 2000-08-29
NO984923L (no) 1998-10-22
IE960307A1 (en) 1997-11-05
IL126422A (en) 2004-02-19
JP3155013B2 (ja) 2001-04-09
NZ332018A (en) 2000-06-23
ES2234014T3 (es) 2005-06-16
ATE282653T1 (de) 2004-12-15
AU727340C (en) 2001-11-08
PL329598A1 (en) 1999-03-29
JP3335995B2 (ja) 2002-10-21
EP1479707A2 (de) 2004-11-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee