ATE282653T1 - Saure polymilchsäure polymere - Google Patents

Saure polymilchsäure polymere

Info

Publication number
ATE282653T1
ATE282653T1 AT97917392T AT97917392T ATE282653T1 AT E282653 T1 ATE282653 T1 AT E282653T1 AT 97917392 T AT97917392 T AT 97917392T AT 97917392 T AT97917392 T AT 97917392T AT E282653 T1 ATE282653 T1 AT E282653T1
Authority
AT
Austria
Prior art keywords
acid units
acid polylactic
polylactic polymers
polymers
biodegradable polyesters
Prior art date
Application number
AT97917392T
Other languages
English (en)
Inventor
Thomas Ciaran Loughman
Ruth Mary Russell
Frank Jean-Claude Touraud
Original Assignee
Ipsen Mfg Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Mfg Ireland Ltd filed Critical Ipsen Mfg Ireland Ltd
Application granted granted Critical
Publication of ATE282653T1 publication Critical patent/ATE282653T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/91Polymers modified by chemical after-treatment
    • C08G63/912Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/60Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from the reaction of a mixture of hydroxy carboxylic acids, polycarboxylic acids and polyhydroxy compounds
AT97917392T 1996-04-23 1997-04-22 Saure polymilchsäure polymere ATE282653T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IE1997/000031 WO1997040085A2 (en) 1996-04-23 1997-04-22 Acidic polylactic polymers
IE960307A IE960307A1 (en) 1996-04-23 1998-10-07 Acidic polylactic polymers

Publications (1)

Publication Number Publication Date
ATE282653T1 true ATE282653T1 (de) 2004-12-15

Family

ID=11041149

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97917392T ATE282653T1 (de) 1996-04-23 1997-04-22 Saure polymilchsäure polymere

Country Status (18)

Country Link
US (1) US6111033A (de)
EP (3) EP0895517B1 (de)
JP (2) JP3155013B2 (de)
AT (1) ATE282653T1 (de)
AU (1) AU727340C (de)
CA (1) CA2250981C (de)
CZ (1) CZ299398A3 (de)
DE (2) DE69731623T4 (de)
DK (1) DK0895517T3 (de)
ES (1) ES2234014T3 (de)
HU (1) HUP0000732A3 (de)
IE (1) IE960307A1 (de)
IL (1) IL126422A (de)
NO (1) NO984923D0 (de)
NZ (1) NZ332018A (de)
PL (1) PL329598A1 (de)
RU (1) RU2165942C2 (de)
WO (1) WO1997040085A2 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221958B1 (en) * 1993-01-06 2001-04-24 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19640269A1 (de) * 1996-09-30 1998-04-02 Basf Ag Verwendung einer wäßrigen Dispersion eines biologisch abbaubaren Polyesters zur Umhüllung von Düngemittelgranulaten
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
UA54505C2 (uk) 1997-04-03 2003-03-17 Гілфорд Фармасьютікалз Інк. Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання
IL132120A0 (en) 1997-04-03 2001-03-19 Guilford Pharm Inc Biodegradable terephthalate polyester-poly (phosphate) polymers compositions articles and methods for making and using the same
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
US6310171B1 (en) * 1997-10-29 2001-10-30 Kanebo Limited Resin composition with biodegradability and foamability
US6548302B1 (en) 1998-06-18 2003-04-15 Johns Hopkins University School Of Medicine Polymers for delivery of nucleic acids
US6419709B1 (en) 1998-10-02 2002-07-16 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same
US6153212A (en) 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
US6350464B1 (en) 1999-01-11 2002-02-26 Guilford Pharmaceuticals, Inc. Methods for treating ovarian cancer, poly (phosphoester) compositions, and biodegradable articles for same
US6537585B1 (en) 1999-03-26 2003-03-25 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
US7109166B1 (en) 1999-08-18 2006-09-19 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Sustained release formulation of a peptide
EP1348444B1 (de) * 1999-08-18 2006-04-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist
CZ2002333A3 (cs) * 1999-08-18 2002-08-14 Societe De Conseils De Recherches Et D'application Sloučenina 1 obsahující sloučeninu A, farmaceutický prostředek a pouľití sloučeniny A pro výrobu léčiva pro léčení chorob
JP4565290B2 (ja) * 1999-12-01 2010-10-20 東洋紡績株式会社 高水酸基濃度を有するオキシ酸系脂肪族ポリエステルおよびオキシ酸系脂肪族ポリエステル組成物
JP3450810B2 (ja) 2000-01-31 2003-09-29 キヤノン株式会社 脂肪族ポリエステル、脂肪族ポリエステルの製造方法およびセルロースの再資源化方法
FR2821360B1 (fr) * 2001-02-27 2003-05-30 Sod Conseils Rech Applic Procede de preparation de polyesters avec des fonctions acides libres intracatenaires
US20030045798A1 (en) * 2001-09-04 2003-03-06 Richard Hular Multisensor probe for tissue identification
US7479535B2 (en) 2002-02-25 2009-01-20 Guilford Pharmaceuticals, Inc. Phosphorous-containing compounds with polymeric chains, and methods of making and using the same
BR122018074353B8 (pt) 2003-01-28 2021-07-27 Ironwood Pharmaceuticals Inc composição farmacêutica, polipeptídeo e métodos para a produção dos mesmos
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
ATE551339T1 (de) 2003-11-05 2012-04-15 Sarcode Bioscience Inc Modulatoren der zellulären adhäsion
KR20050054129A (ko) * 2003-12-04 2005-06-10 주식회사 삼양사 고분자 미셀을 형성하는 생분해성 분지형 폴리락트산유도체, 및 그의 제조방법 및 용도
US7597897B2 (en) * 2003-12-30 2009-10-06 3M Innovative Properties Company Medicinal compositions and method for the preparation thereof
SI1881823T1 (sl) 2005-05-17 2015-04-30 Sarcode Bioscience Inc. Sestavki in postopki za zdravljenje bolezni oäśesa
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CN101772513B (zh) 2007-06-04 2013-11-13 协同医药品公司 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
CA3105972A1 (en) 2007-10-19 2009-04-30 Novartis Ag Compositions and methods for treatment of diabetic retinopathy
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
WO2011096968A1 (en) * 2010-02-08 2011-08-11 Danimer Scientific, Llc Degradable polymers for hydrocarbon extraction
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103635446B (zh) 2011-05-04 2016-02-03 巴兰斯医疗公司 戊四唑衍生物
WO2013042677A1 (ja) * 2011-09-20 2013-03-28 東洋紡株式会社 ポリ乳酸系ポリエステル樹脂、ポリ乳酸系ポリエステル樹脂水分散体、水性接着剤、及びポリ乳酸系ポリエステル樹脂水分散体の製造方法
RU2467029C1 (ru) * 2011-10-25 2012-11-20 Российская Федерация, От Имени Которой Выступает Министерство Промышленности И Торговли Российской Федерации Способ получения биоразлагаемых полиэфиров
WO2013122245A1 (ja) * 2012-02-17 2013-08-22 東洋紡株式会社 ポリ乳酸系ポリエステル樹脂、ポリ乳酸系ポリエステル樹脂水分散体、及びポリ乳酸系ポリエステル樹脂水分散体の製造方法
JP6133847B2 (ja) * 2012-04-27 2017-05-24 株式会社クレハ ポリエステル樹脂組成物およびその成形体
US10675376B2 (en) * 2012-05-24 2020-06-09 Ethicon Llc Mechanically strong absorbable polymeric blend compositions of precisely controllable absorption rates, processing methods, and products therefrom
EP2877465A4 (de) 2012-07-25 2016-05-11 Sarcode Bioscience Inc Lfa-1-hemmer und polymorph davon
KR101548314B1 (ko) * 2012-12-17 2015-08-28 주식회사 엘지화학 폴리락타이드 수지의 제조방법
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
US20140274820A1 (en) * 2013-03-15 2014-09-18 Danimer Scientific, Llc Degradable polymers and method for fracking applications
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
CA2926691A1 (en) 2013-10-10 2015-04-16 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
EP3402804A1 (de) 2016-01-11 2018-11-21 Synergy Pharmaceuticals Inc. Formulierungen und verfahren zur behandlung von colitis ulcerosa
RU2715383C1 (ru) * 2019-06-20 2020-02-27 Общество с ограниченной ответственностью "ТВС" Способ получения (со)полимера гликолида и/или лактида для изготовления рассасывающихся хирургических изделий

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4523591A (en) * 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
DE3936191C2 (de) * 1989-10-31 1996-10-17 Boehringer Ingelheim Kg Neue Copolymere aus Milchsäure und Weinsäure, ihre Herstellung sowie ihre Verwendung
JPH0665230A (ja) * 1992-08-19 1994-03-08 Showa Denko Kk ラクチドの製造方法
EP0678018B1 (de) * 1993-01-06 2003-04-09 Kinerton Limited Ionische molekularkonjugate von bioabbaubaren polyestern und bioaktiven polypeptiden
US5672659A (en) * 1993-01-06 1997-09-30 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
AU706434B2 (en) * 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation

Also Published As

Publication number Publication date
JP3155013B2 (ja) 2001-04-09
EP0895517B1 (de) 2004-11-17
CZ299398A3 (cs) 1999-01-13
EP1479707A2 (de) 2004-11-24
DE69731623D1 (de) 2004-12-23
AU727340B2 (en) 2000-12-07
DE69731623T4 (de) 2006-08-31
PL329598A1 (en) 1999-03-29
US6111033A (en) 2000-08-29
WO1997040085A2 (en) 1997-10-30
EP0895517A2 (de) 1999-02-10
DE69731623T2 (de) 2005-10-06
AU2575297A (en) 1997-11-12
CA2250981A1 (en) 1997-10-30
NO984923L (no) 1998-10-22
HUP0000732A2 (en) 2000-07-28
IE960307A1 (en) 1997-11-05
JP3335995B2 (ja) 2002-10-21
RU2165942C2 (ru) 2001-04-27
NZ332018A (en) 2000-06-23
NO984923D0 (no) 1998-10-22
JP2001181378A (ja) 2001-07-03
IL126422A0 (en) 1999-05-09
IL126422A (en) 2004-02-19
ES2234014T3 (es) 2005-06-16
WO1997040085A3 (en) 1998-01-22
DK0895517T3 (da) 2005-01-17
EP1479708A3 (de) 2005-05-25
EP1479708A2 (de) 2004-11-24
HUP0000732A3 (en) 2000-11-28
CA2250981C (en) 2002-07-02
EP1479707A3 (de) 2005-05-18
AU727340C (en) 2001-11-08
JPH11508640A (ja) 1999-07-27

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