KR100561122B1 - 서열화를 위해 변형시킨 열안정성 디엔에이 폴리머라제 - Google Patents

서열화를 위해 변형시킨 열안정성 디엔에이 폴리머라제 Download PDF

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Publication number
KR100561122B1
KR100561122B1 KR1019980037299A KR19980037299A KR100561122B1 KR 100561122 B1 KR100561122 B1 KR 100561122B1 KR 1019980037299 A KR1019980037299 A KR 1019980037299A KR 19980037299 A KR19980037299 A KR 19980037299A KR 100561122 B1 KR100561122 B1 KR 100561122B1
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South Korea
Prior art keywords
amino acid
xaa
labeled
polymerase
dna polymerase
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Expired - Fee Related
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KR1019980037299A
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English (en)
Korean (ko)
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KR19990029676A (ko
Inventor
데이비드 에이치 겔판드
리사 비비안 칼만
토마스 더블유 마이어스
프레드 로렌스 렐케르트
크리스토퍼 림 시구아
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에프. 호프만-라 로슈 아게
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Publication of KR19990029676A publication Critical patent/KR19990029676A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019980037299A 1997-09-11 1998-09-10 서열화를 위해 변형시킨 열안정성 디엔에이 폴리머라제 Expired - Fee Related KR100561122B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5852597P 1997-09-11 1997-09-11
US60/058,525 1997-09-11

Publications (2)

Publication Number Publication Date
KR19990029676A KR19990029676A (ko) 1999-04-26
KR100561122B1 true KR100561122B1 (ko) 2006-07-25

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KR1019980037299A Expired - Fee Related KR100561122B1 (ko) 1997-09-11 1998-09-10 서열화를 위해 변형시킨 열안정성 디엔에이 폴리머라제

Country Status (17)

Country Link
US (3) US6346379B1 (enExample)
EP (1) EP0902035B1 (enExample)
JP (1) JP4417452B2 (enExample)
KR (1) KR100561122B1 (enExample)
CN (1) CN1197962C (enExample)
AT (1) ATE530567T1 (enExample)
AU (1) AU741366B2 (enExample)
BR (1) BR9803419B1 (enExample)
CA (1) CA2243985C (enExample)
CZ (1) CZ293217B6 (enExample)
ES (1) ES2374910T3 (enExample)
HU (1) HUP9802024A3 (enExample)
IL (1) IL126100A (enExample)
NO (1) NO327476B1 (enExample)
PL (1) PL328525A1 (enExample)
RU (1) RU2238978C2 (enExample)
TW (1) TW513439B (enExample)

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BR9803419B1 (pt) 2010-09-21
CN1218832A (zh) 1999-06-09
CZ287498A3 (cs) 1999-03-17
EP0902035A3 (en) 1999-06-23
US20020142333A1 (en) 2002-10-03
US20030152988A1 (en) 2003-08-14
KR19990029676A (ko) 1999-04-26
JP4417452B2 (ja) 2010-02-17
NO327476B1 (no) 2009-07-13
AU741366B2 (en) 2001-11-29
IL126100A (en) 2005-12-18
ES2374910T3 (es) 2012-02-23
HK1018796A1 (en) 2000-01-07
US7598032B2 (en) 2009-10-06
TW513439B (en) 2002-12-11
CZ293217B6 (cs) 2004-03-17
IL126100A0 (en) 1999-05-09
NO984157L (no) 1999-03-12
PL328525A1 (en) 1999-03-15
EP0902035B1 (en) 2011-10-26
CA2243985C (en) 2004-08-10
US6346379B1 (en) 2002-02-12
ATE530567T1 (de) 2011-11-15
HU9802024D0 (en) 1998-12-28
RU2238978C2 (ru) 2004-10-27
JPH11137284A (ja) 1999-05-25
EP0902035A2 (en) 1999-03-17
CN1197962C (zh) 2005-04-20
HUP9802024A2 (hu) 1999-05-28
NO984157D0 (no) 1998-09-10
HUP9802024A3 (en) 2001-02-28
BR9803419A (pt) 2000-02-08
AU8416198A (en) 1999-03-25
CA2243985A1 (en) 1999-03-11

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