KR100496063B1 - 신규단백질 및 그 제조방법 - Google Patents
신규단백질 및 그 제조방법 Download PDFInfo
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- KR100496063B1 KR100496063B1 KR10-2003-7009671A KR20037009671A KR100496063B1 KR 100496063 B1 KR100496063 B1 KR 100496063B1 KR 20037009671 A KR20037009671 A KR 20037009671A KR 100496063 B1 KR100496063 B1 KR 100496063B1
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- G—PHYSICS
- G01—MEASURING; TESTING
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- Health & Medical Sciences (AREA)
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| JP33224197 | 1997-12-02 | ||
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IL117175A (en) | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| US7632922B1 (en) * | 1995-12-22 | 2009-12-15 | Amgen, Inc. | Osteoprotegerin |
| US20050147611A1 (en) * | 1995-12-22 | 2005-07-07 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
| DE122010000046I1 (de) * | 1996-12-13 | 2011-05-05 | Schering Corp | Oberflächenantigene aus Säugern |
| DE951551T1 (de) * | 1996-12-23 | 2000-09-14 | Immunex Corp., Seattle | Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie |
| US6271349B1 (en) | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
| ES2263204T5 (es) | 1997-04-15 | 2013-10-14 | Daiichi Sankyo Company, Limited | Nueva proteína y proceso para producir la misma |
| US6316408B1 (en) * | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| AU2011202547B2 (en) * | 1997-04-16 | 2014-08-28 | Amgen Inc. | Osteoprotegerin binding proteins and receptors |
| US5843678A (en) * | 1997-04-16 | 1998-12-01 | Amgen Inc. | Osteoprotegerin binding proteins |
| RO128635A2 (ro) * | 1997-04-16 | 2013-07-30 | Amgen Inc. | Anticorp sau fragment al acestuia care se leagă la opgbp şi utilizarea acestuia, utilizarea unei forme solubile de odar, şi metodă de identificare a unui compus care descreşte activitatea opgbp |
| EP2009025B1 (en) | 1998-05-14 | 2011-07-27 | Immunex Corporation | Method of inhibiting osteoclast activity |
| IL142557A0 (en) | 1998-10-28 | 2002-03-10 | Snow Brand Milk Products Co Ltd | Remedies for bone metabolic errors |
| AUPQ314799A0 (en) * | 1999-09-29 | 1999-10-21 | University Of Western Australia, The | Bone cell factor |
| US20030103978A1 (en) * | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
| MXPA02008144A (es) † | 2000-02-23 | 2002-11-29 | Amgen Inc | Agentes de enlace selectivos antagonistas de la proteina de enlace de osteoprotegerina. |
| DE01973455T1 (de) | 2000-09-22 | 2004-04-22 | Immunex Corp., Seattle | Screeningverfahren für agonisten und antagonisten des rezeptoraktivators von nf-kappa b |
| WO2002062990A1 (fr) * | 2001-02-07 | 2002-08-15 | Sankyo Company, Limited | Anticorps et utilisation de cet anticorps |
| WO2002079256A1 (fr) * | 2001-03-26 | 2002-10-10 | Sankyo Company, Limited | Anticorps et son utilisation |
| AU2002253133B2 (en) | 2001-04-03 | 2008-02-28 | Societe Des Produits Nestle S.A. | Osteoprotegerin in milk |
| DK2270052T3 (en) | 2001-06-26 | 2018-07-02 | Amgen Inc | Antibodies to OPGL |
| JP4761710B2 (ja) | 2002-04-05 | 2011-08-31 | アムジェン インコーポレイテッド | 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体 |
| US7462700B2 (en) * | 2002-12-10 | 2008-12-09 | Schering-Plough Animal Health Corporation | Canine RANKL and methods for preparing and using the same |
| US20050009097A1 (en) * | 2003-03-31 | 2005-01-13 | Better Marc D. | Human engineered antibodies to Ep-CAM |
| US7318925B2 (en) | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
| CN1838968A (zh) | 2003-08-08 | 2006-09-27 | 艾伯吉尼斯公司 | 针对甲状旁腺激素(pth)之抗体和其用途 |
| AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| PT2311873T (pt) | 2004-01-07 | 2018-11-20 | Novartis Vaccines & Diagnostics Inc | Anticorpo monoclonal específico para m-csf e respetivos usos |
| TWI359026B (en) * | 2004-02-12 | 2012-03-01 | Sankyo Co | Pharmaceutical composition for the osteoclast rela |
| RU2324425C2 (ru) * | 2005-08-30 | 2008-05-20 | Государственное образовательное учреждение "Институт усовершенствования врачей" Министерства здравоохранения и социального развития | Способ профилактики рождения больных остеопетрозом детей |
| PE20070684A1 (es) | 2005-11-14 | 2007-08-06 | Amgen Inc | MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| WO2007093050A1 (en) * | 2006-02-13 | 2007-08-23 | Olga Ornatsky | Gene expression assays conducted by elemental analysis |
| EP2020445B1 (en) | 2006-05-12 | 2013-01-02 | Keio University | Detection of inflammatory disease and composition for prevention or treatment of inflammatory disease |
| WO2008044379A1 (fr) | 2006-10-11 | 2008-04-17 | Oriental Yeast Co., Ltd. | Modèle animal de perte osseuse |
| WO2008044797A1 (fr) | 2006-10-11 | 2008-04-17 | Oriental Yeast Co., Ltd. | Animal modèle d'ostéopénie |
| AU2007305855A1 (en) | 2006-10-11 | 2008-04-17 | Oriental Yeast Co., Ltd. | Agent containing fused protein of soluble RANKL with epitope tag |
| WO2008150025A1 (ja) | 2007-06-05 | 2008-12-11 | Oriental Yeast Co., Ltd. | 新しい骨量増加薬 |
| SG10201605897RA (en) | 2007-10-11 | 2016-09-29 | Daiichi Sankyo Co Ltd | ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN Siglec-15 |
| US8778359B2 (en) * | 2008-07-30 | 2014-07-15 | Emergent Biosolutions Inc. | Stable anthrax vaccine formulations |
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| NZ631509A (en) | 2012-03-30 | 2016-09-30 | Daiichi Sankyo Co Ltd | Cdr-modified anti-siglec-15 antibody |
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| CN105555291B (zh) | 2013-08-07 | 2021-08-24 | 助育公司 | 用于治疗雄性不育症的抗体、化合物及其衍生物 |
| EP3086780A4 (en) | 2013-12-27 | 2017-08-09 | Emergent Product Development Gaithersburg Inc. | Temperature stable vaccine formulations |
| BR112019004901A2 (pt) * | 2016-09-13 | 2019-06-25 | E&S Healthcare Co., Ltd. | anticorpo monoclonal ou um fragmento de ligação ao antígeno do mesmo, seu método de preparação, molécula de ácido nucleico, vetor recombinante, célula hospedeira, kit de diagnóstico e método para fornecer informações |
| CN108410990B (zh) * | 2018-05-30 | 2021-07-06 | 中国医学科学院北京协和医院 | Igfbp3在制备诊断i型神经纤维瘤合并脊柱畸形病产品中的应用 |
| CN111205354B (zh) * | 2020-01-22 | 2021-01-22 | 天津科技大学 | 一种提高异源蛋白分泌量的信号肽突变体及其构建方法与用途 |
| CN111333709B (zh) * | 2020-03-17 | 2023-09-08 | 吉林大学 | 旋毛虫肌幼虫期丝氨酸蛋白酶抑制剂的b细胞表位多肽、杂交瘤细胞株、单克隆抗体及应用 |
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