RU2238949C2 - Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты) - Google Patents

Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты) Download PDF

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RU2238949C2
RU2238949C2 RU99100615/13A RU99100615A RU2238949C2 RU 2238949 C2 RU2238949 C2 RU 2238949C2 RU 99100615/13 A RU99100615/13 A RU 99100615/13A RU 99100615 A RU99100615 A RU 99100615A RU 2238949 C2 RU2238949 C2 RU 2238949C2
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Prior art keywords
protein
ocif
obm
cells
dna
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RU99100615/13A
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Russian (ru)
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RU99100615A (ru
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Киодзи ЯМАГУТИ (JP)
Киодзи Ямагути
Хисатака ЯСУДА (JP)
Хисатака Ясуда
Нобуаки НАКАГАВА (JP)
Нобуаки Накагава
Нобуюки СИМА (JP)
Нобуюки Сима
Масахико КИНОСАКИ (JP)
Масахико Киносаки
Еисуке ТСУДА (JP)
Еисуке Тсуда
Масааки ГОТО (JP)
Масааки Гото
Казуки ЯНО (JP)
Казуки Яно
Акихиро ТОМОЯСУ (JP)
Акихиро Томоясу
Фумие КОБАЯСИ (JP)
Фумие Кобаяси
Наохиро ВАСИДА (JP)
Наохиро Васида
Кен ТАКАХАСИ (JP)
Кен Такахаси
Томонори МОРИНАГА (JP)
Томонори Моринага
Кандзи ХИГАСИО (JP)
Кандзи Хигасио
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Санкио Компани Лимитед
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RU99100615/13A 1997-04-15 1998-04-15 Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты) RU2238949C2 (ru)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
JP9780897 1997-04-15
JP9/97808 1997-04-15
JP15143497 1997-06-09
JP9/151434 1997-06-09
JP21789797 1997-08-12
JP9/217897 1997-08-12
JP9/224803 1997-08-21
JP22480397 1997-08-21
JP9/332241 1997-12-02
JP33224197 1997-12-02
PCT/JP1998/001728 WO1998046644A1 (fr) 1997-04-15 1998-04-15 Nouvelle proteine et methode de production associee

Publications (2)

Publication Number Publication Date
RU99100615A RU99100615A (ru) 2000-11-20
RU2238949C2 true RU2238949C2 (ru) 2004-10-27

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ID=27525882

Family Applications (1)

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RU99100615/13A RU2238949C2 (ru) 1997-04-15 1998-04-15 Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты)

Country Status (21)

Country Link
US (7) US7527790B2 (enExample)
EP (3) EP1657255B1 (enExample)
JP (7) JP3523650B2 (enExample)
KR (1) KR100496063B1 (enExample)
CN (1) CN1138786C (enExample)
AT (1) ATE328006T1 (enExample)
AU (1) AU735355B2 (enExample)
CA (2) CA2781623A1 (enExample)
CY (1) CY2010017I2 (enExample)
DE (2) DE122010000049I1 (enExample)
DK (1) DK0911342T4 (enExample)
ES (1) ES2263204T5 (enExample)
FR (1) FR10C0048I2 (enExample)
HU (3) HU229841B1 (enExample)
IL (1) IL127115A (enExample)
LU (1) LU91759I2 (enExample)
NO (2) NO322632B1 (enExample)
NZ (1) NZ332995A (enExample)
PT (1) PT911342E (enExample)
RU (1) RU2238949C2 (enExample)
WO (1) WO1998046644A1 (enExample)

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RU2324425C2 (ru) * 2005-08-30 2008-05-20 Государственное образовательное учреждение "Институт усовершенствования врачей" Министерства здравоохранения и социального развития Способ профилактики рождения больных остеопетрозом детей
RU2539790C2 (ru) * 2009-04-09 2015-01-27 Дайити Санкио Компани, Лимитед АНТИТЕЛО ПРОТИВ Siglec-15
US9090692B2 (en) 2007-10-11 2015-07-28 Daiichi Sankyo Company, Limited Antibody targeting osteoclast-related protein Siglec-15
US9114131B2 (en) 2010-10-05 2015-08-25 Daiichi Sankyo Company, Limited Antibody targeting osteoclast-related protein Siglec-15
RU2596392C2 (ru) * 2009-10-06 2016-09-10 Алетиа Байотерапьютикс Инк. Антитела против сиглека-15 для лечения заболевания, связанного с потерей костной массы
US9464133B2 (en) 2012-03-30 2016-10-11 Daiichi Sankyo Company, Limited CDR-modified anti-Siglec-15 antibody
RU2747929C2 (ru) * 2016-09-13 2021-05-17 ИэндЭС ХЕЛТКЕАР КО., ЛТД. Моноклональное антитело, специфически связывающееся с тиоредоксином-1, и его применение

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ATE399861T1 (de) * 1996-12-13 2008-07-15 Schering Corp Oberflächenantigene aus säugern
US6017729A (en) 1996-12-23 2000-01-25 Immunex Corporation Receptor activator of NF-κB
US6271349B1 (en) 1996-12-23 2001-08-07 Immunex Corporation Receptor activator of NF-κB
CA2781623A1 (en) 1997-04-15 1998-10-22 Daiichi Sankyo Company, Limited Novel protein binding to osteoclastogenesis inhibitory factor and process for producing the same
ID23855A (id) * 1997-04-16 2000-05-25 Amgen Inc Protein pengikat osteoprotegerin dan reseptor
US5843678A (en) * 1997-04-16 1998-12-01 Amgen Inc. Osteoprotegerin binding proteins
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MXPA02008144A (es) 2000-02-23 2002-11-29 Amgen Inc Agentes de enlace selectivos antagonistas de la proteina de enlace de osteoprotegerina.
US20030103978A1 (en) * 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
WO2002024896A2 (en) 2000-09-22 2002-03-28 Immunex Corporation Screening assays for agonists or antagonists of receptor activat or of nf-kb
WO2002062990A1 (fr) * 2001-02-07 2002-08-15 Sankyo Company, Limited Anticorps et utilisation de cet anticorps
WO2002079256A1 (fr) * 2001-03-26 2002-10-10 Sankyo Company, Limited Anticorps et son utilisation
EP1377610A2 (en) 2001-04-03 2004-01-07 Société des Produits Nestlé S.A. Osteoprotegerin in milk
NO345566B1 (no) 2001-06-26 2021-04-19 Amgen Inc OPGL bindende antistoff, farmasøytisk sammensetning samt anvendelse derav
CA2481074A1 (en) 2002-04-05 2003-10-23 Amgen Inc. Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
MXPA05006147A (es) * 2002-12-10 2005-08-26 Schering Plough Ltd Ligando del activador del receptor de nf-kb de canino, y metodos para preparar y usar el mismo.
US20050009097A1 (en) * 2003-03-31 2005-01-13 Better Marc D. Human engineered antibodies to Ep-CAM
JP2007521232A (ja) 2003-08-08 2007-08-02 アブジェニックス・インコーポレーテッド 副甲状腺ホルモン(pth)に対する抗体およびその使用
US7318925B2 (en) 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
AR045563A1 (es) 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
BRPI0506726B8 (pt) 2004-01-07 2021-05-25 Chiron Corp anticorpo monoclonal específico para m-csf e usos deste
TWI359026B (en) * 2004-02-12 2012-03-01 Sankyo Co Pharmaceutical composition for the osteoclast rela
TW200736277A (en) 2005-11-14 2007-10-01 Amgen Inc RANKL antibody-PTH/PTHrP chimeric molecules
CN101384733A (zh) * 2006-02-13 2009-03-11 奥尔加·奥尔纳茨基 通过元素分析实施的基因表达检测
EP2020445B1 (en) 2006-05-12 2013-01-02 Keio University Detection of inflammatory disease and composition for prevention or treatment of inflammatory disease
WO2008044379A1 (fr) 2006-10-11 2008-04-17 Oriental Yeast Co., Ltd. Modèle animal de perte osseuse
WO2008044797A1 (fr) 2006-10-11 2008-04-17 Oriental Yeast Co., Ltd. Animal modèle d'ostéopénie
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