KR100388583B1 - 글루카곤-유사형인슐린분비촉진착체,조성물및방법 - Google Patents

글루카곤-유사형인슐린분비촉진착체,조성물및방법 Download PDF

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Publication number
KR100388583B1
KR100388583B1 KR1019950012728A KR19950012728A KR100388583B1 KR 100388583 B1 KR100388583 B1 KR 100388583B1 KR 1019950012728 A KR1019950012728 A KR 1019950012728A KR 19950012728 A KR19950012728 A KR 19950012728A KR 100388583 B1 KR100388583 B1 KR 100388583B1
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South Korea
Prior art keywords
glp
gly
histidine
ala
val
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Expired - Fee Related
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KR1019950012728A
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English (en)
Korean (ko)
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KR960034219A (ko
Inventor
존앨리슨갤로웨이
제임스아더호프만
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일라이 릴리 앤드 캄파니
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019950012728A 1995-03-21 1995-05-22 글루카곤-유사형인슐린분비촉진착체,조성물및방법 Expired - Fee Related KR100388583B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/407,831 1995-03-21
US08/407,831 US5705483A (en) 1993-12-09 1995-03-21 Glucagon-like insulinotropic peptides, compositions and methods

Publications (2)

Publication Number Publication Date
KR960034219A KR960034219A (ko) 1996-10-22
KR100388583B1 true KR100388583B1 (ko) 2003-09-13

Family

ID=23613700

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950012728A Expired - Fee Related KR100388583B1 (ko) 1995-03-21 1995-05-22 글루카곤-유사형인슐린분비촉진착체,조성물및방법

Country Status (28)

Country Link
US (7) US5705483A (https=)
EP (2) EP1364967B1 (https=)
JP (3) JP3502694B2 (https=)
KR (1) KR100388583B1 (https=)
CN (1) CN1185257C (https=)
AT (2) ATE312119T1 (https=)
AU (1) AU708159B2 (https=)
BR (1) BR9503036A (https=)
CA (1) CA2150080A1 (https=)
CO (1) CO4650140A1 (https=)
CZ (1) CZ292972B6 (https=)
DE (2) DE69534678T2 (https=)
DK (2) DK0733644T3 (https=)
ES (2) ES2218536T3 (https=)
FI (1) FI952536L (https=)
HU (1) HUT74729A (https=)
IL (2) IL113809A (https=)
MY (1) MY134820A (https=)
NO (1) NO322837B1 (https=)
NZ (1) NZ272186A (https=)
PE (1) PE23296A1 (https=)
PL (1) PL182113B1 (https=)
PT (1) PT733644E (https=)
RU (1) RU2147588C1 (https=)
SI (1) SI1364967T1 (https=)
TW (1) TW389769B (https=)
UA (1) UA44696C2 (https=)
ZA (1) ZA954141B (https=)

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US6388053B1 (en) 2002-05-14
PL182113B1 (pl) 2001-11-30
ES2250789T3 (es) 2006-04-16
US5705483A (en) 1998-01-06
US6410513B1 (en) 2002-06-25
US6703365B2 (en) 2004-03-09
CN1185257C (zh) 2005-01-19
FI952536L (fi) 1996-09-22
US7232879B2 (en) 2007-06-19
PT733644E (pt) 2004-07-30
PE23296A1 (es) 1996-06-15
US5977071A (en) 1999-11-02
CZ292972B6 (cs) 2004-01-14
IL113809A (en) 2000-07-26
IL134853A0 (en) 2001-05-20
CZ132195A3 (en) 1996-10-16
RU2147588C1 (ru) 2000-04-20
DE69534678D1 (de) 2006-01-12
RU95108231A (ru) 1997-03-20
JP3502694B2 (ja) 2004-03-02
DE69532914T2 (de) 2005-03-31
EP0733644A1 (en) 1996-09-25
TW389769B (en) 2000-05-11
ES2218536T3 (es) 2004-11-16
US6133235A (en) 2000-10-17
JPH08269097A (ja) 1996-10-15
EP0733644B1 (en) 2004-04-21
EP1364967B1 (en) 2005-12-07
ATE264869T1 (de) 2004-05-15
CN1131674A (zh) 1996-09-25
NO952034D0 (no) 1995-05-23
HU9501508D0 (en) 1995-07-28
AU708159B2 (en) 1999-07-29
IL113809A0 (en) 1995-08-31
HUT74729A (en) 1997-02-28
DK1364967T3 (da) 2006-03-27
UA44696C2 (uk) 2002-03-15
BR9503036A (pt) 1997-09-23
NO952034L (no) 1996-09-23
JP2003048899A (ja) 2003-02-21
MY134820A (en) 2007-12-31
ATE312119T1 (de) 2005-12-15
EP1364967A3 (en) 2004-01-28
PL308783A1 (en) 1996-09-30
AU2026895A (en) 1996-10-03
US20020165342A1 (en) 2002-11-07
KR960034219A (ko) 1996-10-22
DE69532914D1 (de) 2004-05-27
DK0733644T3 (da) 2004-08-16
DE69534678T2 (de) 2006-09-07
NO322837B1 (no) 2006-12-11
US20040127399A1 (en) 2004-07-01
NZ272186A (en) 1997-01-29
JP2004002480A (ja) 2004-01-08
EP1364967A2 (en) 2003-11-26
SI1364967T1 (sl) 2006-04-30
CO4650140A1 (es) 1998-09-03
ZA954141B (en) 1996-11-22

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