JPH11504018A5 - - Google Patents

Info

Publication number
JPH11504018A5
JPH11504018A5 JP1996532038A JP53203896A JPH11504018A5 JP H11504018 A5 JPH11504018 A5 JP H11504018A5 JP 1996532038 A JP1996532038 A JP 1996532038A JP 53203896 A JP53203896 A JP 53203896A JP H11504018 A5 JPH11504018 A5 JP H11504018A5
Authority
JP
Japan
Prior art keywords
oligosaccharides
sulfated
sulfate
activity
heparanase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1996532038A
Other languages
English (en)
Japanese (ja)
Other versions
JP4514240B2 (ja
JPH11504018A (ja
Filing date
Publication date
Priority claimed from AUPN2618A external-priority patent/AUPN261895A0/en
Application filed filed Critical
Publication of JPH11504018A publication Critical patent/JPH11504018A/ja
Publication of JPH11504018A5 publication Critical patent/JPH11504018A5/ja
Application granted granted Critical
Publication of JP4514240B2 publication Critical patent/JP4514240B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP53203896A 1995-04-28 1996-04-24 硫酸化オリゴ糖の製造および使用 Expired - Lifetime JP4514240B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPN2618A AUPN261895A0 (en) 1995-04-28 1995-04-28 Preparation and use of sulfated oligosaccharides
PCT/AU1996/000238 WO1996033726A1 (en) 1995-04-28 1996-04-24 Preparation and use of sulfated oligosaccharides
AU2618 1998-03-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009138310A Division JP2009235085A (ja) 1995-04-28 2009-06-09 硫酸化オリゴ糖の製造および使用

Publications (3)

Publication Number Publication Date
JPH11504018A JPH11504018A (ja) 1999-04-06
JPH11504018A5 true JPH11504018A5 (enExample) 2009-08-06
JP4514240B2 JP4514240B2 (ja) 2010-07-28

Family

ID=3786969

Family Applications (2)

Application Number Title Priority Date Filing Date
JP53203896A Expired - Lifetime JP4514240B2 (ja) 1995-04-28 1996-04-24 硫酸化オリゴ糖の製造および使用
JP2009138310A Withdrawn JP2009235085A (ja) 1995-04-28 2009-06-09 硫酸化オリゴ糖の製造および使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009138310A Withdrawn JP2009235085A (ja) 1995-04-28 2009-06-09 硫酸化オリゴ糖の製造および使用

Country Status (26)

Country Link
US (1) US6143730A (enExample)
EP (1) EP0837683B1 (enExample)
JP (2) JP4514240B2 (enExample)
KR (1) KR100591960B1 (enExample)
CN (1) CN1090021C (enExample)
AT (1) ATE463250T1 (enExample)
AU (1) AUPN261895A0 (enExample)
BR (1) BR9608041B8 (enExample)
CA (1) CA2218872C (enExample)
CZ (1) CZ341097A3 (enExample)
DE (1) DE69638158D1 (enExample)
EA (1) EA001199B1 (enExample)
EE (1) EE9700277A (enExample)
ES (1) ES2341924T3 (enExample)
FI (1) FI974060A0 (enExample)
HU (1) HUP9802394A2 (enExample)
IL (1) IL118047A (enExample)
IS (1) IS4596A (enExample)
NO (1) NO974911L (enExample)
NZ (1) NZ305815A (enExample)
PL (1) PL184357B1 (enExample)
PT (1) PT837683E (enExample)
TR (1) TR199701264T1 (enExample)
TW (1) TW446710B (enExample)
WO (1) WO1996033726A1 (enExample)
ZA (1) ZA963339B (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO556297A0 (en) * 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
ES2200366T3 (es) * 1997-08-28 2004-03-01 University Of Washington Composiciones de sacaridos para el tratamiento de la enfermedad de alzheimer y otras amiloidoisis.
AUPO888497A0 (en) * 1997-09-01 1997-09-25 Australian National University, The Use of sulfated oligosaccharides as inhibitors of cardiovascular disease
AUPO976897A0 (en) * 1997-10-14 1997-11-06 Australian National University, The Use of sulfated oligosaccharides in lowering blood triglyceride levels
GB9802725D0 (en) 1998-02-09 1998-04-08 Ciba Geigy Ag Organic compounds
US7081448B2 (en) * 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) * 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6083933A (en) * 1999-04-19 2000-07-04 Stellar International Inc. Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution
US20040220103A1 (en) 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
GB0001481D0 (en) * 2000-01-21 2000-03-15 Theryte Ltd System for delivering a medicament
GB0003048D0 (en) * 2000-02-11 2000-03-29 Dealler Stephen F The therapeutic use of polysulphonated polyglycosides or other polyanionic compounds in autism
FR2808687B1 (fr) * 2000-04-27 2003-12-05 Goemar Lab Sa Medicament contenant des substances polysaccharidiques pour l'activation de l'apoptose
JP4676048B2 (ja) * 2000-07-10 2011-04-27 生化学工業株式会社 脱髄性疾患処置剤
US7407773B2 (en) * 2000-11-03 2008-08-05 Procognia, Ltd. Method for characterizing a carbohydrate polymer
TW519716B (en) * 2000-12-19 2003-02-01 Tokyo Electron Ltd Wafer bias drive for a plasma source
EP1353556A4 (en) 2001-01-23 2009-09-09 Massachusetts Inst Technology SYNTHESIS OF HEPARIN AND OTHER GLYCOSAMINOGLYCANS IN SOLID PHASE AND SOLUTION PHASE
CN1394867A (zh) * 2001-07-06 2003-02-05 中国科学院生态环境研究中心 可作药物的寡糖和其制备方法及含该寡糖的药物组合物
CZ307433B6 (cs) 2001-09-12 2018-08-22 Leadiant Biosciences Sa Deriváty částečně desulfátovaných glykosaminoglykanů jako inhibitory heparanázy mající antiangiogenní účinky a zabraňující antikoagulačnímu působení
KR20030046810A (ko) * 2001-12-06 2003-06-18 은삼제약 주식회사 콘드로이친 황산의 분해산물을 포함하는 관절염 예방 또는치료용 약학적 조성물
AUPS052802A0 (en) * 2002-02-15 2002-03-07 Praxis Pharmaceuticals International Pty Ltd Carbohydrate-based anti-wrinkle and tissue remodelling compounds
WO2003078960A2 (en) * 2002-03-11 2003-09-25 Momenta Pharmaceuticals, Inc. Analysis of sulfated polysaccharides
US20040161476A1 (en) 2003-02-19 2004-08-19 Hahn Sungtack Samuel Cystitis treatment with high dose chondroitin sulfate
WO2005054493A2 (en) * 2003-06-12 2005-06-16 Mayo Foundation For Medical Education And Research Altered activity of toll-like receptors
JP5139797B2 (ja) * 2004-03-04 2013-02-06 プロジェン ファーマシューティカルズ リミテッド 硫酸化オリゴ糖誘導体
CN101588808A (zh) * 2006-10-20 2009-11-25 澳大利亚国立大学 对细胞外基质降解的抑制
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
US20100160253A1 (en) * 2007-05-31 2010-06-24 Glycan Biosciences Sulphated xylans for treatment or prophylaxis of respiratory diseases
US8153611B2 (en) * 2007-06-28 2012-04-10 Basf Beauty Care Solutions France S.A.S. Use of sulfated oligosaccharides as slimming cosmetic ingredients
ES2700111T3 (es) * 2007-06-28 2019-02-14 Basf Beauty Care Solutions France Sas Composición adelgazante
FR2917971B1 (fr) 2007-06-28 2009-10-23 Engelhard Lyon Soc Par Actions Composition amincissante
RU2483074C2 (ru) * 2007-10-16 2013-05-27 Проджен Фармасьютикалз Лимитед Новые сульфатированные производные олигосахаридов
US20100266558A1 (en) * 2007-12-18 2010-10-21 Dov Zipori Method and assay for glycosylation pattern detection related to cell state of stem cells
JP2011522805A (ja) * 2008-05-30 2011-08-04 モメンタ ファーマシューティカルズ インコーポレイテッド 糖構造ならびにそのような構造を作製および使用する方法
EP2149580A1 (en) 2008-07-15 2010-02-03 Istituto Scientifico di Chimica E Biochimica "G Ronzoni Mimetics of sulfated oligosaccharides
US8232073B2 (en) 2009-01-02 2012-07-31 Zacharon Pharmaceuticals, Inc. Quantification of non-reducing end glycan residual compounds
US8809009B2 (en) 2009-01-02 2014-08-19 Biomarin Pharmaceutical Inc. Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker
US9029530B2 (en) 2009-01-02 2015-05-12 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
US8592140B2 (en) 2009-01-02 2013-11-26 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
GB0915315D0 (en) * 2009-09-03 2009-10-07 Univ Manchester Use of non-digestible oligosaccharides
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
US8435795B2 (en) * 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
JPWO2011122321A1 (ja) * 2010-03-29 2013-07-08 国立大学法人名古屋大学 ヘパリン結合性蛋白に対する生理活性阻害剤
NZ611316A (en) * 2010-12-01 2014-12-24 Univ Australian Histone inhibition
CA2827383A1 (en) * 2011-02-18 2012-08-23 President And Fellows Of Harvard College Molecular switch for neuronal outgrowth
US9068957B2 (en) 2011-02-21 2015-06-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN102199175A (zh) * 2011-04-07 2011-09-28 福州大学 硫酸类肝素二糖的制备纯化方法及其纯化产品
CN107362168A (zh) 2011-06-09 2017-11-21 基亚生物科技股份有限公司 用于抑制肝癌复发、恶化或转移之医药组成物
CA2861077A1 (en) * 2012-01-30 2013-08-08 Baxter International Inc. Non-anticoagulant sulfated or sulfonated polysaccharides
EP2997047B1 (en) * 2013-05-16 2021-04-28 Agency For Science, Technology And Research Heparan sulphates
WO2015172040A2 (en) 2014-05-08 2015-11-12 Immunexcite, Inc. IMMUNOMODULATING β-1,6-D-GLUCANS
SE538503C2 (en) * 2014-11-11 2016-08-16 Tx Medic Ab New dextran sulfate
CZ306662B6 (cs) * 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
CN105504097B (zh) * 2015-12-30 2018-07-03 深圳市海普瑞药业集团股份有限公司 一种硫酸化肝素寡糖及其制备方法和应用
JP2016199579A (ja) * 2016-07-08 2016-12-01 基亜生物科技股▲ふん▼有限公司Ｍｅｄｉｇｅｎ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐ． 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
BR112019012045A2 (pt) 2016-12-13 2020-08-18 Beta Therapeutics Pty Ltd inibidores de heparanase e uso dos mesmos
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
EP3723862A4 (en) * 2017-12-12 2021-08-25 Academia Sinica OCTASACCHARIDES AND THEIR USES
WO2019113646A1 (en) * 2017-12-15 2019-06-20 Griffith University Sulfation method
JP6619830B2 (ja) * 2018-02-22 2019-12-11 基亜生物科技股▲ふん▼有限公司Ｍｅｄｉｇｅｎ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐ． 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
NL2024493B1 (en) * 2019-12-16 2021-09-02 Logick Energetics B V Pharmaceutical composition for preventing or stopping metastases
CN114828846B (zh) 2019-12-18 2025-04-18 罗吉科能量有限公司 用于预防或阻止转移的医药组合物
CN110917208B (zh) * 2019-12-27 2021-02-12 浙江医院 硫酸化甘露葡萄糖醛酸六糖在防治动脉粥样硬化中的应用
CN111904968A (zh) * 2020-08-21 2020-11-10 青岛市中心医院 硫酸半乳四糖及其衍生物在制备抗上皮细胞黏附药物中的应用
CN113633658A (zh) * 2021-07-09 2021-11-12 南京理工大学 硫酸葡半乳寡聚糖在制备抗凝血和/或抗血栓药物中的应用
CN114134188B (zh) * 2021-07-23 2023-03-17 光明乳业股份有限公司 一种发酵小麦麸皮合成胞外多糖的方法
CN115646378A (zh) * 2022-09-15 2023-01-31 哈尔滨工业大学 一种生物质胶质凝胶及其制备方法、应用
CN116650425B (zh) * 2023-07-13 2025-06-27 晟迪生物医药(苏州)有限公司 糖酯化合物或其盐在冷冻保护、冷冻干燥保护中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA869530B (en) * 1985-12-24 1987-10-28 Marion Laboratories Inc Use of synthetic sulfated saccharides to enhance wound healing
FR2597484B1 (fr) * 1986-04-17 1988-12-23 Sanofi Sa Glycosaminoglycanes de type heparine ou heparane-sulfate dotes d'une activite sur la division et la differentiation cellulaires, leur preparation et leurs applications therapeutiques.
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
WO1989003684A1 (fr) * 1987-10-30 1989-05-05 Chugai Seiyaku Kabushiki Kaisha Agent anti-vih
US5506210A (en) * 1988-08-19 1996-04-09 The Australian National University Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
JPH0296588A (ja) * 1988-09-29 1990-04-09 Rikagaku Kenkyusho 硫酸化オリゴ糖及びその関連物質
JP2956090B2 (ja) * 1989-10-30 1999-10-04 大日本インキ化学工業株式会社 オリゴ糖誘導体
WO1992003453A1 (en) * 1990-08-23 1992-03-05 Dainippon Ink & Chemicals, Inc. Antiviral agent
CA2061370A1 (en) * 1991-03-13 1992-09-14 Markus Hosang Pharmaceutical preparations
JPH06506973A (ja) * 1991-04-17 1994-08-04 グライコメッド　インコーポレイテッド 平滑筋細胞増殖のインヒビターとしての硫酸化多糖類
JPH06256373A (ja) * 1993-01-11 1994-09-13 Dainippon Ink & Chem Inc 硫酸化オリゴ糖配糖体アシル化物およびこれを有効成分とする抗ウイルス剤
US5459257A (en) * 1993-01-11 1995-10-17 Dainippon Ink And Chemicals, Inc. Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient
FR2710741B1 (fr) * 1993-09-30 1995-10-27 Commissariat Energie Atomique Capteur électronique destiné à la caractérisation de grandeurs physiques et procédé de réalisation d'un tel capteur.
EP0722326A4 (en) * 1993-10-07 1999-10-06 Glycomed Inc HIGHLY SULFATED MALTOOLIGOSSACCHARIDES WITH HEPARIN-LIKE PROPERTIES
US5739115A (en) * 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties

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