JP7679173B2 - Ｒａｆ（急速進行性線維肉腫）ポリペプチドの標的分解のための化合物および方法 - Google Patents

Ｒａｆ（急速進行性線維肉腫）ポリペプチドの標的分解のための化合物および方法 Download PDF

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JP7679173B2
JP7679173B2 JP2019534245A JP2019534245A JP7679173B2 JP 7679173 B2 JP7679173 B2 JP 7679173B2 JP 2019534245 A JP2019534245 A JP 2019534245A JP 2019534245 A JP2019534245 A JP 2019534245A JP 7679173 B2 JP7679173 B2 JP 7679173B2
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JP2020504741A (ja
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クルー，アンドリュー・ピィ
ホーンバーガー，キース・アール
ワン，ジン
ドン，ハンチン
チエン，イミン
クルーズ，クレイグ・エム
ジェイミー－フィゲロア，サウル
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Yale University
Arvinas Operations Inc
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JP2019534245A 2016-12-23 2017-12-22 Ｒａｆ（急速進行性線維肉腫）ポリペプチドの標的分解のための化合物および方法 Active JP7679173B2 (ja)

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JP2023015526A JP2023065395A (ja) 2016-12-23 2023-02-03 Ｒａｆ（急速進行性線維肉腫）ポリペプチドの標的分解のための化合物および方法
JP2024180795A JP2025016525A (ja) 2016-12-23 2024-10-16 Ｒａｆ（急速進行性線維肉腫）ポリペプチドの標的分解のための化合物および方法

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US201662438803P 2016-12-23 2016-12-23
US62/438,803 2016-12-23
US201762582698P 2017-11-07 2017-11-07
US62/582,698 2017-11-07
PCT/US2017/068322 WO2018119448A1 (en) 2016-12-23 2017-12-22 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides

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CN107412788B (zh) 2012-12-21 2021-06-18 国立研究开发法人量子科学技术研究开发机构 用于对脑内所蓄积的Tau蛋白质进行成像的新的化合物
CA2933701C (en) 2013-12-18 2022-05-31 The California Institute For Biomedical Research Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
US20180228907A1 (en) 2014-04-14 2018-08-16 Arvinas, Inc. Cereblon ligands and bifunctional compounds comprising the same
JP6817962B2 (ja) 2015-01-20 2021-01-20 アルビナス・オペレーションズ・インコーポレイテッドＡｒｖｉｎａｓ Ｏｐｅｒａｔｉｏｎｓ， Ｉｎｃ． ターゲティングされたアンドロゲン受容体分解のための化合物および方法
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