JP7441955B2 - インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用 - Google Patents

インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用 Download PDF

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JP7441955B2
JP7441955B2 JP2022543052A JP2022543052A JP7441955B2 JP 7441955 B2 JP7441955 B2 JP 7441955B2 JP 2022543052 A JP2022543052 A JP 2022543052A JP 2022543052 A JP2022543052 A JP 2022543052A JP 7441955 B2 JP7441955 B2 JP 7441955B2
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aminoethoxy
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JPWO2021146441A5 (enExample
JP2023511552A (ja
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サン，チェンザオ
トロイ フレデリック，ブライアン
ソマニ，サンディープ
トマス ボーン，グレゴリー
パッチ，レイモンド
バンダリ，アショク
インジェニート，ラファエル
コスタンテ，ロベルト
ブランカ，ダニラ
ビアンキ，エリザベッタ
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ヤンセン バイオテツク，インコーポレーテツド
プロタゴニスト セラピューティクス， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
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  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2022543052A 2020-01-15 2021-01-14 インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用 Active JP7441955B2 (ja)

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JP2023119000A JP2023139158A (ja) 2020-01-15 2023-07-21 インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用

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US202062961624P 2020-01-15 2020-01-15
US62/961,624 2020-01-15
PCT/US2021/013463 WO2021146441A1 (en) 2020-01-15 2021-01-14 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

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JP2023119000A Pending JP2023139158A (ja) 2020-01-15 2023-07-21 インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用

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US (2) US11845808B2 (enExample)
EP (2) EP4090670B1 (enExample)
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CN (5) CN118005736A (enExample)
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DO (1) DOP2022000147A (enExample)
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ES (1) ES3036287T3 (enExample)
FI (1) FI4090670T3 (enExample)
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JO (1) JOP20220169A1 (enExample)
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PH (1) PH12022551750A1 (enExample)
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WO2021146454A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
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CA3226539A1 (en) * 2021-07-14 2023-01-19 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor
EP4370146A4 (en) 2021-07-14 2025-05-21 Janssen Biotech, Inc. Lipidated peptide inhibitors of the interleukin-23 receptor
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JP2025506374A (ja) 2022-02-01 2025-03-11 ヤンセン ファーマシューティカ エヌ．ベー． インターロイキン－２３受容体のペプチド阻害剤及びその医薬組成物
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EP4652179A1 (en) * 2023-01-16 2025-11-26 Janssen Pharmaceutica NV Lipidated peptide inhibitors of interleukin-23 receptor
AU2024210741A1 (en) * 2023-01-16 2025-09-04 Janssen Pharmaceutica Nv Peptide inhibitors of interleukin-23 receptor
EP4652180A2 (en) * 2023-01-16 2025-11-26 Janssen Pharmaceutica NV Peptide inhibitors of interleukin-23 receptor
CN120659801A (zh) 2023-01-31 2025-09-16 詹森药业有限公司 用于制备白介素-23受体的结晶肽抑制剂的方法
WO2024186613A1 (en) * 2023-03-03 2024-09-12 Janssen Pharmaceutica Nv Interleukin-23 receptor antagonist peptides for use in the treatment of psoriasis
WO2024227437A1 (zh) * 2023-05-04 2024-11-07 西藏海思科制药有限公司 白介素-23受体的肽抑制剂制备及其用途
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WO2025051912A1 (en) * 2023-09-08 2025-03-13 Sanofi New peptides as selective il-23 receptor inhibitors
WO2025163534A1 (en) 2024-01-31 2025-08-07 Janssen Pharmaceutica Nv Crystal form of a peptide inhibitor of interleukin-23 receptor
WO2025243217A1 (en) * 2024-05-22 2025-11-27 Janssen Pharmaceutica Nv Crystal forms of peptide molecules
CN120905324A (zh) * 2025-10-10 2025-11-07 北京元延医药科技股份有限公司 白细胞介素-23受体肽抑制剂及其手性中间体的制法

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