GR1006896B - Μεθοδος παραγωγης μιας πεπτιδικης ορμονης - Google Patents
Μεθοδος παραγωγης μιας πεπτιδικης ορμονηςInfo
- Publication number
- GR1006896B GR1006896B GR20070100553A GR20070100553A GR1006896B GR 1006896 B GR1006896 B GR 1006896B GR 20070100553 A GR20070100553 A GR 20070100553A GR 20070100553 A GR20070100553 A GR 20070100553A GR 1006896 B GR1006896 B GR 1006896B
- Authority
- GR
- Greece
- Prior art keywords
- producing
- peptide hormone
- hepcidin
- novel
- provides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
Abstract
Η παρούσα εφεύρεση παρέχει μια καινοτόμο μέθοδο για παραγωγή βιολογικά λειτουργικής εψιδίνης. Η εφεύρεση παρέχει νέα σημασμένη εψιδίνη, αντισώματα και τη χρήση τους στην θεραπεία και σε ανοσοδοκιμασίες.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20070100553A GR1006896B (el) | 2007-08-24 | 2007-08-24 | Μεθοδος παραγωγης μιας πεπτιδικης ορμονης |
AU2008291842A AU2008291842A1 (en) | 2007-08-24 | 2008-08-22 | Process for producing hepcidin |
US12/675,007 US8614068B2 (en) | 2007-08-24 | 2008-08-22 | Process for producing hepcidin |
EP08788798A EP2195339A2 (en) | 2007-08-24 | 2008-08-22 | A process for producing hepcidin |
PCT/GR2008/000056 WO2009027752A2 (en) | 2007-08-24 | 2008-08-22 | Process for producing hepcidin |
KR1020107006382A KR20100065335A (ko) | 2007-08-24 | 2008-08-22 | 헵시딘을 제조하는 방법 |
CA2697976A CA2697976A1 (en) | 2007-08-24 | 2008-08-22 | A process for producing a peptide hormone |
JP2010521489A JP2010536364A (ja) | 2007-08-24 | 2008-08-22 | ペプチドホルモンの生成工程 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20070100553A GR1006896B (el) | 2007-08-24 | 2007-08-24 | Μεθοδος παραγωγης μιας πεπτιδικης ορμονης |
Publications (2)
Publication Number | Publication Date |
---|---|
GR20070100553A GR20070100553A (el) | 2009-03-17 |
GR1006896B true GR1006896B (el) | 2010-07-20 |
Family
ID=40219993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20070100553A GR1006896B (el) | 2007-08-24 | 2007-08-24 | Μεθοδος παραγωγης μιας πεπτιδικης ορμονης |
Country Status (8)
Country | Link |
---|---|
US (1) | US8614068B2 (el) |
EP (1) | EP2195339A2 (el) |
JP (1) | JP2010536364A (el) |
KR (1) | KR20100065335A (el) |
AU (1) | AU2008291842A1 (el) |
CA (1) | CA2697976A1 (el) |
GR (1) | GR1006896B (el) |
WO (1) | WO2009027752A2 (el) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8609817B2 (en) * | 2008-08-06 | 2013-12-17 | Eli Lilly And Company | Anti-hepcidin-25 selective antibodies and uses thereof |
WO2011020886A1 (de) | 2009-08-20 | 2011-02-24 | Vifor (International) Ag | Neue chinolin-hepcidin-antagonisten |
AR077958A1 (es) | 2009-08-27 | 2011-10-05 | Vifor Int Ag | Quinoxalinonas antagonistas de la hepcidina |
AR077999A1 (es) | 2009-09-02 | 2011-10-05 | Vifor Int Ag | Antagonistas de pirimidin y triazin-hepcidina |
CN102712587A (zh) | 2009-09-07 | 2012-10-03 | 维福(国际)股份公司 | 新型乙二胺铁调素拮抗剂 |
WO2011029832A1 (de) | 2009-09-09 | 2011-03-17 | Vifor (International) Ag | Neue thiazol- und oxazol-hepcidin-antagonisten |
US20120214803A1 (en) | 2011-02-18 | 2012-08-23 | Vifor (International) Ag | Novel Sulfonaminoquinoline Hepcidin Antagonists |
SG11201507226YA (en) | 2013-03-15 | 2015-10-29 | Protagonist Therapeutics Inc | Hepcidin analogues and uses therof |
RS62392B1 (sr) | 2014-05-16 | 2021-10-29 | Protagonist Therapeutics Inc | Tioetar peptidni antagonisti alfa4beta7 integrina |
CN107075574A (zh) * | 2014-06-27 | 2017-08-18 | 领导医疗有限公司 | 铁调素和微型铁调素类似物及其用途 |
SG11201700327WA (en) | 2014-07-17 | 2017-02-27 | Protagonist Therapeutics Inc | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
WO2016054445A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | Novel cyclic monomer and dimer peptides having integrin antagonist activity |
AU2015328002A1 (en) | 2014-10-01 | 2017-04-27 | Protagonist Therapeutics, Inc. | Novel alpha4beta7 peptide monomer and dimer antagonists |
US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
WO2017117411A1 (en) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
US10407468B2 (en) | 2016-03-23 | 2019-09-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing α4β7 peptide antagonists |
US11834696B2 (en) * | 2017-04-05 | 2023-12-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Antimicrobial susceptibility testing with large-volume light scattering imaging and deep learning video microscopy |
US10278957B2 (en) | 2017-09-11 | 2019-05-07 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
CN109593766A (zh) * | 2018-12-11 | 2019-04-09 | 武汉大北农水产科技有限公司 | 草鱼铁调素基因及其编码的重组蛋白和应用 |
AU2020311395A1 (en) | 2019-07-10 | 2022-02-03 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
BR112022013957A2 (pt) | 2020-01-15 | 2022-10-11 | Janssen Biotech Inc | Inibidores peptídicos do receptor de interleucina-23 e uso dos mesmos para tratar doenças inflamatórias |
JP7397239B2 (ja) | 2020-11-20 | 2023-12-12 | ヤンセン ファーマシューティカ エヌ.ベー. | インターロイキン-23受容体のペプチド阻害剤の組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7411048B2 (en) * | 2002-11-19 | 2008-08-12 | Drg International, Inc. | Diagnostic method for diseases by screening for hepcidin in human or animal tissues, blood or body fluids |
CA2506668C (en) | 2002-11-19 | 2014-08-19 | Drg International, Inc. | Diagnostic method for diseases by screening for hepcidin in human or animal tissues, blood or body fluids and therapeutic uses therefor |
US7723063B2 (en) * | 2004-04-28 | 2010-05-25 | Intrinsic Lifesciences | Methods for measuring levels of bioactive human hepcidin |
-
2007
- 2007-08-24 GR GR20070100553A patent/GR1006896B/el active IP Right Grant
-
2008
- 2008-08-22 WO PCT/GR2008/000056 patent/WO2009027752A2/en active Application Filing
- 2008-08-22 CA CA2697976A patent/CA2697976A1/en not_active Abandoned
- 2008-08-22 US US12/675,007 patent/US8614068B2/en active Active
- 2008-08-22 KR KR1020107006382A patent/KR20100065335A/ko not_active Application Discontinuation
- 2008-08-22 AU AU2008291842A patent/AU2008291842A1/en not_active Abandoned
- 2008-08-22 JP JP2010521489A patent/JP2010536364A/ja active Pending
- 2008-08-22 EP EP08788798A patent/EP2195339A2/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU2008291842A1 (en) | 2009-03-05 |
JP2010536364A (ja) | 2010-12-02 |
GR20070100553A (el) | 2009-03-17 |
WO2009027752A3 (en) | 2009-06-11 |
EP2195339A2 (en) | 2010-06-16 |
WO2009027752A2 (en) | 2009-03-05 |
KR20100065335A (ko) | 2010-06-16 |
CA2697976A1 (en) | 2009-03-05 |
US8614068B2 (en) | 2013-12-24 |
US20110097749A1 (en) | 2011-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PG | Patent granted |