CL2022001893A1 - Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. - Google Patents

Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.

Info

Publication number
CL2022001893A1
CL2022001893A1 CL2022001893A CL2022001893A CL2022001893A1 CL 2022001893 A1 CL2022001893 A1 CL 2022001893A1 CL 2022001893 A CL2022001893 A CL 2022001893A CL 2022001893 A CL2022001893 A CL 2022001893A CL 2022001893 A1 CL2022001893 A1 CL 2022001893A1
Authority
CL
Chile
Prior art keywords
interleukin
peptide inhibitors
inflammatory diseases
treat inflammatory
receptor peptide
Prior art date
Application number
CL2022001893A
Other languages
English (en)
Inventor
Elisabetta Bianchi
Danila Branca
Chengzao Sun
Brian Troy Frederick
Sandeep Somani
Gregory Thomas Bourne
Raymond Patch
Ashok Bhandari
Raffaele Ingenito
Roberto Costante
Original Assignee
Janssen Biotech Inc
Protagonist Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc, Protagonist Therapeutics Inc filed Critical Janssen Biotech Inc
Publication of CL2022001893A1 publication Critical patent/CL2022001893A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención proporciona nuevos péptidos inhibidores del receptor de interleucina-23 y composiciones y métodos relacionados para usar estos inhibidores de péptidos para tratar o prevenir una variedad de enfermedades y trastornos, incluidas las enfermedades inflamatorias del intestino.
CL2022001893A 2020-01-15 2022-07-13 Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. CL2022001893A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202062961624P 2020-01-15 2020-01-15

Publications (1)

Publication Number Publication Date
CL2022001893A1 true CL2022001893A1 (es) 2023-03-03

Family

ID=76864704

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022001893A CL2022001893A1 (es) 2020-01-15 2022-07-13 Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.

Country Status (20)

Country Link
US (2) US11845808B2 (es)
EP (1) EP4090670A1 (es)
JP (2) JP7441955B2 (es)
KR (1) KR20220141807A (es)
CN (5) CN118005736A (es)
AR (1) AR121070A1 (es)
AU (1) AU2021207653A1 (es)
BR (1) BR112022013957A2 (es)
CA (1) CA3167751A1 (es)
CL (1) CL2022001893A1 (es)
CO (1) CO2022009931A2 (es)
CR (1) CR20220332A (es)
DO (1) DOP2022000147A (es)
EC (1) ECSP22063238A (es)
IL (1) IL294680A (es)
JO (1) JOP20220169A1 (es)
MX (1) MX2022008741A (es)
PE (1) PE20230370A1 (es)
TW (1) TW202140517A (es)
WO (1) WO2021146441A1 (es)

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MX2022008740A (es) 2020-01-15 2022-09-23 Janssen Biotech Inc Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.
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KR20240111800A (ko) 2021-12-01 2024-07-17 질랜드 파마 에이/에스 인터루킨-23 수용체의 펩티드 억제제
IL314629A (en) 2022-02-01 2024-09-01 Janssen Pharmaceutica Nv Peptide inhibitors of the interleukin-23 receptor and pharmaceutical preparations thereof
WO2023177452A1 (en) * 2022-03-14 2023-09-21 Colorado Chromatography, Llc Hydrogenation of cannabigerol and cannabichromene
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US20240218014A1 (en) * 2022-11-21 2024-07-04 Janssen Pharmaceutica Nv Synthesis of a cyclic peptide
WO2024114762A1 (zh) * 2022-11-30 2024-06-06 上海翰森生物医药科技有限公司 一种多肽抑制剂、其制备方法和应用
WO2024155547A2 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Peptide inhibitors of interleukin-23 receptor
WO2024155553A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Lipidated peptide inhibitors of interleukin-23 receptor
WO2024155546A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Peptide inhibitors of interleukin-23 receptor
WO2024163643A1 (en) 2023-01-31 2024-08-08 Janssen Pharmaceutica Nv Methods for preparing crystalline peptide inhibitors of interleukin-23 receptor
WO2024186613A1 (en) * 2023-03-03 2024-09-12 Janssen Pharmaceutica Nv Interleukin-23 receptor antagonist peptides for use in the treatment of psoriasis

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