AR126457A1 - Inhibidores peptídicos bicíclicos del receptor de interleuquina-23 - Google Patents

Inhibidores peptídicos bicíclicos del receptor de interleuquina-23

Info

Publication number
AR126457A1
AR126457A1 ARP220101855A ARP220101855A AR126457A1 AR 126457 A1 AR126457 A1 AR 126457A1 AR P220101855 A ARP220101855 A AR P220101855A AR P220101855 A ARP220101855 A AR P220101855A AR 126457 A1 AR126457 A1 AR 126457A1
Authority
AR
Argentina
Prior art keywords
receptor
peptide inhibitors
interleukine
bicyclic peptide
interleukin
Prior art date
Application number
ARP220101855A
Other languages
English (en)
Inventor
Chengzao Sun
Sandeep Somani
Stephanie A Barros
Raymond J Patch
Santhosh Francis Neelamkavil
Jing Zhang
Charles Hendrick
Elisabetta Bianchi
Roberto Constante
Raffaele Ingenito
Danila Branca
Ashok Bhandari
Brian Frederick
Tran Trung Tran
Jie Zhang
Original Assignee
Janssen Biotech Inc
Protagonist Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc, Protagonist Therapeutics Inc filed Critical Janssen Biotech Inc
Publication of AR126457A1 publication Critical patent/AR126457A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)

Abstract

La presente invención se refiere a nuevos inhibidores peptídicos bicíclicos del receptor de la interleucina-23 (IL-23R) o sales farmacéuticamente aceptables del mismo, composiciones farmacéuticas correspondientes, métodos y/o usos para el tratamiento de la inflamación autoinmune y enfermedades y trastornos relacionados.
ARP220101855A 2021-07-14 2022-07-14 Inhibidores peptídicos bicíclicos del receptor de interleuquina-23 AR126457A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163221854P 2021-07-14 2021-07-14

Publications (1)

Publication Number Publication Date
AR126457A1 true AR126457A1 (es) 2023-10-11

Family

ID=84920518

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP220101855A AR126457A1 (es) 2021-07-14 2022-07-14 Inhibidores peptídicos bicíclicos del receptor de interleuquina-23

Country Status (10)

Country Link
EP (1) EP4370532A2 (es)
JP (1) JP2024525723A (es)
KR (1) KR20240034223A (es)
CN (1) CN117980320A (es)
AR (1) AR126457A1 (es)
AU (1) AU2022310347A1 (es)
CA (1) CA3226492A1 (es)
MX (1) MX2024000761A (es)
TW (1) TW202321275A (es)
WO (1) WO2023288017A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2968443T (pt) 2013-03-15 2021-12-28 Protagonist Therapeutics Inc Análogos de hepcidina e seus usos
LT3143037T (lt) 2014-05-16 2021-10-11 Protagonist Therapeutics, Inc. Alfa4beta7 integrino tioeterio peptidų antagonistaii
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
MX2022008740A (es) 2020-01-15 2022-09-23 Janssen Biotech Inc Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias.
IL302996A (en) 2020-11-20 2023-07-01 Janssen Pharmaceutica Nv Compositions of peptide inhibitors of the interleukin-23 receptor
WO2024155551A1 (en) * 2023-01-16 2024-07-25 Janssen Pharmaceutica Nv Polycyclic peptide inhibitors of interleukin-23 receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3201217A4 (en) * 2014-10-01 2018-07-18 Protagonist Therapeutics Inc. Novel cyclic monomer and dimer peptides having integrin antagonist activity
SG10201912066SA (en) * 2015-07-15 2020-02-27 Protagonist Therapeutics Inc Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
JP7100034B2 (ja) * 2016-12-06 2022-07-12 シュティヒティング・ヴォール・デ・テクニシェ・ヴェテンシャッペン 多環式ペプチド及びそれらの調製方法
WO2019034866A1 (en) * 2017-08-14 2019-02-21 Bicyclerd Limited BICYCLIC PEPTIDE LIGANDS CONJUGATES AND USES THEREOF
MX2020006290A (es) * 2017-12-15 2020-12-03 Janssen Biotech Inc Dinucleotidos ciclicos como agonistas de sting.

Also Published As

Publication number Publication date
KR20240034223A (ko) 2024-03-13
EP4370532A2 (en) 2024-05-22
CN117980320A (zh) 2024-05-03
JP2024525723A (ja) 2024-07-12
WO2023288017A2 (en) 2023-01-19
CA3226492A1 (en) 2023-01-19
MX2024000761A (es) 2024-04-18
AU2022310347A1 (en) 2024-02-29
TW202321275A (zh) 2023-06-01
WO2023288017A3 (en) 2023-03-09

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